77
107
20
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—20
Evidence suggests Ketogenic Diet maydecreaseInflammation.
195 studies (204 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| Diets enriched with antioxidants, omega-3 fatty acids, and anti-inflammatory compounds-such as the Mediterranean diet | Decreases - have shown potential in reducing | oxidative stress and systemic inflammation | Human | — | Not specified | Nutritional and Microbiota-Based Approaches in Amyotrophic Lateral Sclerosis: From Prevention to Treatment.cited 5× |
| high-fructose diet (HFD) | Increases - triggered | inflammation in the jejunum | Animal | Sprague-Dawley rats | 10% fructose solution in drinking water (HFD group), 1.5 mg/kg/day THC (THC groups) | Effects of ∆-9 tetrahydrocannabinol on the small intestine altered by high fructose diet: A Histopathological study.cited 1× |
| high-fructose diet | Increases - caused | uterine inflammation | Animal | Wistar albino rats | Not specified (high-fructose diet for 15 weeks; metformin administered once daily for the last 6 weeks) | Impact of high-fructose diet and metformin on histomorphological and molecular parameters of reproductive organs and vaginal microbiota of female rat.cited 1× |
| high-fat/high-fructose diet plus O. viverrini infection | Increases - aggravates the progression by augmenting | inflammation | Animal | male golden hamsters | Not specified (described as "high-fat/high-fructose diet"). | High-fat/high-fructose diet and Opisthorchis viverrini infection promote metabolic dysfunction-associated steatotic liver disease via inflammation, fibrogenesis, and metabolic dysfunction. |
| diet and diet plus exercise | Decreases - reduced | serum markers of interstitial matrix turnover and inflammation | Human | overweight and obese adults with knee OA | — | Effects of dietary weight loss with and without exercise on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the Intensive Diet and Exercise for Arthritis trial (IDEA). |
| strict gluten-free diet (GFD) | No effect - poses significant challenges | dietary restrictions, cross-contamination and subsequent persistent intestinal inflammation | Human | patients with celiac disease | Not specified | New developments in celiac disease treatments.cited 6× |
| AGE-restricted diet | Decreases - reduces | levels of markers of inflammation | Human | CKD patients before the initiation of dialysis | Not specified | The low AGE diet: a neglected aspect of clinical nephrology practice?cited 15× |
| AGE-restricted diet | Decreases - reduces | levels of markers of inflammation | Human | CKD patients after the initiation of dialysis | Not specified | The low AGE diet: a neglected aspect of clinical nephrology practice?cited 15× |
| AGE-restricted diet | Decreases - reduces | levels of markers of inflammation | Human | a variety of conditions | Not specified | The low AGE diet: a neglected aspect of clinical nephrology practice?cited 15× |
| excessive consumption of advanced glycation end products with the standard western diet | Increases - is a major cause for | inflammation | Human | — | Not specified. | Advanced glycation end products (AGE) and diabetes: cause, effect, or both?cited 406× |
| fish oil-ethanol diet | Increases - developed | fatty liver, inflammation and necrosis | Animal | male Wistar rats | Not specified. | Medium chain triglycerides and vitamin E reduce the severity of established experimental alcoholic liver disease.cited 64× |
| Mismatch between sow late gestation diet and piglet nursery diet | Increases - upregulated | genes involved in inflammation | Animal | piglet hepatic tissues | Sows received 12% or 17% crude protein (CP) during late gestation; piglets received 16.5% or 21% CP post-weaning. | The Impact of Maternal and Piglet Low Protein Diet and Their Interaction on the Porcine Liver Transcriptome around the Time of Weaning.cited 4× |
| milk-based saturated high fat diet (MD, 60% fat) | Increases - showed a higher trend of | inflammation | Animal | Mice | Low-fat control diet (13% fat), lard-based unsaturated high-fat diet (60% fat), milk-based saturated high-fat diet (60% fat). | Unsaturated or saturated dietary fat-mediated steatosis impairs hepatic regeneration following partial hepatectomy in mice.cited 3× |
| unsaturated fat diet | Decreases - cause lower | inflammation | Animal | mice | Low-fat control diet (13% fat), lard-based unsaturated high-fat diet (60% fat), milk-based saturated high-fat diet (60% fat). | Unsaturated or saturated dietary fat-mediated steatosis impairs hepatic regeneration following partial hepatectomy in mice.cited 3× |
| switched from a WD to a standard diet after IL-23 minicircle delivery | Decreases - reduced | joint inflammation | Animal | mice | Not specified (diet composition described as high-sugar, moderate-fat) | Short-Term Western Diet Intake Promotes IL-23‒Mediated Skin and Joint Inflammation Accompanied by Changes to the Gut Microbiota in Mice.cited 46× |
| switched from a WD to a standard diet after IL-23 minicircle delivery | Decreases - reduced | skin inflammation | Animal | mice | Not specified (diet composition described as high-sugar, moderate-fat) | Short-Term Western Diet Intake Promotes IL-23‒Mediated Skin and Joint Inflammation Accompanied by Changes to the Gut Microbiota in Mice.cited 46× |
| exposure to a high-sugar and moderate-fat diet (i.e., Western diet [WD]) | Increases - induces | appreciable skin inflammation | Animal | mice | Not specified (diet composition described as high-sugar, moderate-fat) | Short-Term Western Diet Intake Promotes IL-23‒Mediated Skin and Joint Inflammation Accompanied by Changes to the Gut Microbiota in Mice.cited 46× |
| a high fat diet that is deficient in omega-3 fatty acids | Increases - could promote | obesity and excessive inflammation | Human | — | 3.18 g daily of eicosapentaenoic acid and 822 mg daily of docosahexaenoic acid. | Nutrigenetic response to omega-3 fatty acids in obese asthmatics (NOOA): rationale and methods.cited 13× |
| gluten-free and dairy-free (GF/DF) diet | Decreases - had a major anti-inflammatory effect | inflammation | Human | children with SRNS | Not specified | Immunological Impact of a Gluten-Free Dairy-Free Diet in Children With Kidney Disease: A Feasibility Study.cited 15× |
| a diet rich in omega-3 fatty acids | Decreases - reducing | inflammation | Human | — | Not specified | The challenges of incorporation of omega-3 fatty acids into ration components and their prevalence in garrison feeding.cited 4× |
| low-protein diet | Decreases - decreases | synovial inflammation | AnimalMolecular | — | Not specified | Low-Protein Diet Inhibits the Synovial Tissue Macrophage Pro-Inflammatory Polarization Via NRF2/SIRT3/SOD2/ROS Pathway in K/BxN Rheumatoid Arthritis Mice. |
| Mediterranean diet and its peculiar foods and nutrients | Decreases - exert beneficial effects against | inflammation | Human | — | — | Mediterranean Diet on Sleep: A Health Alliance.cited 51× |
| antioxidants through diet or oral supplementation | Decreases - can counteract the harmful effects | harmful effects of reactive oxygen species accumulated secondary to oxidative stress, ischemia, and inflammation | Human | — | Not specified | Antioxidants and neurodegenerative eye disease.cited 4× |
| Long-term adherence to a high-fibre, polyphenol-enriched and vegetable-protein-based diet | Increases - may offer potential therapies for improvement of | inflammation | Human | — | Not specified | A dietary intervention with functional foods reduces metabolic endotoxaemia and attenuates biochemical abnormalities by modifying faecal microbiota in people with type 2 diabetes.cited 111× |
| supplementation of functional food or drug to the diet | Decreases - inhibiting | hepatic inflammation | Human | — | Not specified | Healthy diet intervention reverses the progression of NASH through gut microbiota modulation.cited 3× |
| Mediterranean diet pattern (MDP) | Decreases - is associated with | beneficial metabolite changes associated with reducing inflammation | Human | patients with UC | Not specified | Metabolomic Signatures Highlight Fiber-Degrading Bacteroides Species in Mediterranean Diet Response Among Ulcerative Colitis. |
| CAF diet | Increases - caused | metabolic abnormalities, insulin resistance and inflammation in serum | Animal | Male C57BL/6 mice | 5 mg/kg/day administered intraperitoneally. | 7,8-Dihydroxyflavone alleviates Endoplasmic Reticulum Stress in cafeteria diet-induced metabolic syndrome.cited 6× |
| high fruit and vegetable (F&V) diet | Decreases - protecting against | systemic inflammation | Human | children with asthma | Increased F&V intake by ~3.5 serves/day (intervention vs. control). | The effects of increasing fruit and vegetable intake in children with asthma: A randomized controlled trial.cited 18× |
| low-calorie and low-protein diet with high contents of fiber, polyunsaturated fatty acids, vitamins, minerals and polyphenols | No effect - modulating | inflammation and immune functions | Human | SLE | Not specified | Immunomodulatory Effects of Diet and Nutrients in Systemic Lupus Erythematosus (SLE): A Systematic Review.cited 64× |
| maintaining an AGE-rich diet | Increases - may increase | oxidative stress and inflammation | Human | mother | Not specified | Possible effects of dietary advanced glycation end products on maternal and fetal health: a review.cited 3× |
| greater adherence to the MIND diet | No effect - associations were partially mediated by | metabolic and inflammation status | Human | 187,490 participants in the UK Biobank | Not specified (dietary intake assessed via 24-hour recall questionnaire). | Greater adherence to the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet is associated with lower risk of inflammatory bowel disease: a prospective cohort study.cited 3× |
| deficient vitamin A diet | No effect - were not significantly different | inflammation | Animal | mice | Deficient (0 IU/g diet), control (4 IU/g diet), copious (25 IU/g diet). | Modest effect of differential dietary vitamin A intake on the pathogenesis of alcohol-associated liver disease.cited 1× |
| copious vitamin A diet | No effect - were not significantly different | inflammation | Animal | mice | Deficient (0 IU/g diet), control (4 IU/g diet), copious (25 IU/g diet). | Modest effect of differential dietary vitamin A intake on the pathogenesis of alcohol-associated liver disease.cited 1× |
| including 50 g of raisins in the diet daily for 6 months | Decreases - evaluate the effect | markers of inflammation | Human | older adults without cognitive impairment | 50 g of raisins daily | Effect of including a dietary supplement of raisins, a food rich in polyphenols, on cognitive function in healthy older adults; a study protocol for a randomized clinical trial.cited 3× |
| traditional Iranian diet (TID) | No effect - did not positively impact | dietary inflammation | Human | RRMS patients | Not specified | Modified Mediterranean dietcited 20× |
| high-fat diet (HFD) | Increases - altered | gene expression associated with WAT inflammation and dysfunction | AnimalMolecular | C57BL/6j mice | Not specified | Fish Oil Supplementation Mitigates High-Fat Diet-Induced Obesity: Exploring Epigenetic Modulation and Genes Associated with Adipose Tissue Dysfunction in Mice.cited 5× |
| high-fat diet (HFD) | Increases - induced | hepatic, cardiac, and brain inflammation | Animal | hypercholestremic adult male rats | — | High-fat diet induced alteration in lipid enzymes and inflammation in cardiac and brain tissues: Assessment of the effects of Atorvastatin-loaded nanoparticles. |
| high fat diet | Increases - leading to | hepatocellular injury and inflammation | Human | patients with NAFLD | Not available | CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease.cited 371× |
| high fat diet | Increases - induce inflammation | inflammation | Animal | — | Not specified | The Significance of Ras Activity in Pancreatic Cancer Initiation.cited 49× |
| high-fat diet (HFD) | Increases - were evident | inflammation | Animal | hepatic tissue | 10mg/kg orally. | Enhancement of biochemical and genomic pathways through lycopene-loaded nano-liposomes: Alleviating insulin resistance, hepatic steatosis, and autophagy in obese rats with non-alcoholic fatty liver disease: Involvement of SMO, GLI-1, and PTCH-1 genes.cited 11× |
| high-fat diet | Increases - increased inflammation | inflammation | Animal | mice subjected to high-fat diet | Not specified (ad libitum access for HF group, 10-hour feeding window for HF-TRF group). | Time-restricted feeding alleviates arthritis symptoms augmented by high-fat diet. |
| high fat diet | Increases - induced | inflammation and macrophage infiltration | HumanAnimal | — | Not specified | Sirt1-PPARS Cross-Talk in Complex Metabolic Diseases and Inherited Disorders of the One Carbon Metabolism.cited 39× |
| high-fat diet (HFD) | Increases - induces | inflammation and oxidative stress | Animal | — | 100 mg/kg/day | Pyridoxine exerts antioxidant effects on kidney injury manifestations in high-fat diet-induced obese rats. |
| high-fat diet (HFD) | Increases - significantly increased | inflammation biomarkers | Animal | male Wistar rats | Not specified | Evaluation of the Anti-Obesity Effect of Zeaxanthin and Exercise in HFD-Induced Obese Rats.cited 9× |
| high-fat diet | Increases - may be modulated by | inflammation of PVAT | HumanAnimalMolecular | animal models and humans | Not specified | Proinflammatory phenotype of perivascular adipocytes.cited 119× |
| high fat diet (HFD) | Increases - leading to | systemic inflammation | Human | individuals consuming a high fat diet (HFD) commonly ingested by those with obesity | Not specified | Depression and obesity: Focus on factors and mechanistic links.cited 5× |
| Very low-calorie ketogenic diet (VLCKD) | Decreases - may reduce | inflammation | Human | — | Not specified (very low-calorie ketogenic diet regimen). | Ketogenic diet improves disease activity and cardiovascular risk in psoriatic arthritis: A proof of concept study. |
| Synbiotics supplementation and adherence to an anti-inflammatory-antioxidant-rich diet | Decreases - reduced | intestinal inflammation | Human | progressive forms of MS | Daily synbiotics capsule plus anti-inflammatory-antioxidant-rich diet (specific dosage not detailed). | Effects of anti-Inflammatory-antioxidant-rich diet and co-supplemented synbiotics intervention in patients with progressive forms of multiple sclerosis: a single-center, single-blind randomized clinical trial.cited 11× |
| a protein enriched and low glycemic index diet supplemented with long-chain omega-3 PUFA | Decreases - reduces | silent inflammation | Human | overweight or obese patients with type 2 diabetes | Not specified | A protein-enriched low glycemic index diet with omega-3 polyunsaturated fatty acid supplementation exerts beneficial effects on metabolic control in type 2 diabetes.cited 15× |
| high-protein (HP) isocaloric diet | No effect - associated with morphological and biochemical differences compatible with higher colonic epithelium restoration | colonic crypt repair after acute inflammation | Animal | surviving animals | Not specified (isocaloric high-protein diet). | Dual effects of a high-protein diet on DSS-treated mice during colitis resolution phase.cited 16× |
| high-protein (HP) isocaloric diet | Increases - was higher | inflammation intensity | Animal | DSS-treated mice | Not specified (isocaloric high-protein diet). | Dual effects of a high-protein diet on DSS-treated mice during colitis resolution phase.cited 16× |
| low glycemic index (GI) diet in pregnancy | No effect - little effect | markers of inflammation | Human | women in pregnancy | Not specified | Impact of a low glycemic index diet in pregnancy on markers of maternal and fetal metabolism and inflammation.cited 20× |
| hypocaloric diet | Decreases - reduces | inflammation | Human | PsA patients who are overweight or obese | Not specified | Role of Anti-Inflammatory Diet and Fecal Microbiota Transplant in Psoriatic Arthritis.cited 2× |
| Mediterranean diet | Decreases - reduces | inflammation | Human | PsA patients who are overweight or obese | Not specified | Role of Anti-Inflammatory Diet and Fecal Microbiota Transplant in Psoriatic Arthritis.cited 2× |
| a diet high in fiber | Decreases - alleviating | obesity-induced chronic inflammation | Human | human and animal studies | Not specified | The interplay between fiber and the intestinal microbiome in the inflammatory response.cited 111× |
| 30%P/43%C diet | Decreases - decreased | intestinal inflammation | Animal | juvenile common carp (Cyprinus carpio) | 0.16% MCS supplementation in the 28%P/46%C diet. | Momordica charantia saponins administration in low-protein-high-carbohydrate diet improves growth, blood biochemical, intestinal health and microflora composition of juvenile common carp (Cyprinus carpio).cited 4× |
| diet rich in bilberries | Decreases - significantly different | inflammation score | Human | subjects with metabolic syndrome | Equivalent to 400 g fresh bilberries daily. | Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome.cited 124× |
| diet rich in bilberries | Decreases - may reduce | low-grade inflammation | Human | subjects with metabolic syndrome | Equivalent to 400 g fresh bilberries daily. | Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome.cited 124× |
| A diet rich in antioxidants | Decreases - can result in prevention | inflammation-related pathologies | Human | null | Not specified. | Comprehensive and critical view on the anti-inflammatory and immunomodulatory role of natural phenolic antioxidants.cited 9× |
| Adding olive oil (OO) and flaxseed oil (FLO) to the diet | Decreases - has been reported to reduce | inflammation | Human | — | Not specified in the abstract. | Supplementation of Olive Oil and Flaxseed Oil on Blood Pressure and Inflammation in Healthy and At-Risk Adults: A Systematic Literature Review and Meta-Analysis.cited 1× |
| gluten-free diet (GFD) alone | No effect - is not sufficient to control | small intestinal inflammation | Human | many patients | Not specified | Celiac disease 2015 update: new therapies.cited 19× |
| Polyphenols in the diet | Increases - help to improve | lipid profiles, blood pressure, insulin resistance, and systemic inflammation | Human | — | Not specified | Health benefits of polyphenols: A concise review.cited 273× |
| low-energy diet | Decreases - decreased inflammation | inflammation | Human | women with obesity | Not specified | Modulation of the gut microbiota by probiotics and symbiotics is associated with changes in serum metabolite profile related to a decrease in inflammation and overall benefits to metabolic health: a double-blind randomized controlled clinical trial in women with obesity.cited 27× |
| low-inflammatory diet based on the principles and recipes of the Mediterranean diet | No effect - can modulate | gastrointestinal markers of inflammation | Human | individuals with FAP | Not specified | Preventive Anti-inflammatory Diet to Reduce Gastrointestinal Inflammation in Familial Adenomatous Polyposis Patients: A Prospective Pilot Study.cited 13× |
| low-inflammatory diet based on the principles and recipes of the Mediterranean diet | Decreases - would reduce | markers of local and systemic inflammation | Human | patients with FAP | Not specified | Preventive Anti-inflammatory Diet to Reduce Gastrointestinal Inflammation in Familial Adenomatous Polyposis Patients: A Prospective Pilot Study.cited 13× |
| personalized diet (RISTOMED diet) | No effect - demonstrated no further effects | inflammation | Human | 62 healthy persons aged 65-85 years | 2 capsules of VSL#3 per day (specific B12 dosage not specified). | Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota - The "RISTOMED project": Randomized controlled trial in healthy older people.cited 82× |
| a diet high in AGEs | Increases - elevated | inflammation | Human | human participants | Not specified | Blood and Tissue Advanced Glycation End Products as Determinants of Cardiometabolic Disorders Focusing on Human Studies.cited 6× |
| Yinchenhao Decoction (YD) supplementation in a high carbohydrate diet (HCD) | Increases - increased the mRNA levels of | anti-inflammation genes (IL-10 and IKBα) | Animal | juvenile largemouth bass | 0.5%, 1%, 2%, or 4% YD supplementation in HCD | Yinchenhao Decoction ameliorates the high-carbohydrate diet induced suppression of immune response in largemouth bass (Micropterus salmoides).cited 16× |
| Yinchenhao Decoction (YD) supplementation in a high carbohydrate diet (HCD) | Decreases - decreased the expressions of | pro-inflammation genes (TNF-α, IL-1β, IL-8, hepcidin1, NF-κB, COX2, CD80 and CD83) | Animal | juvenile largemouth bass | 0.5%, 1%, 2%, or 4% YD supplementation in HCD | Yinchenhao Decoction ameliorates the high-carbohydrate diet induced suppression of immune response in largemouth bass (Micropterus salmoides).cited 16× |
| Yinchenhao Decoction (YD) supplementation in a high carbohydrate diet (HCD) | Decreases - decreases | uncontrolled necroptosis and inflammation | Animal | juvenile largemouth bass | 0.5%, 1%, 2%, or 4% YD supplementation in HCD | Yinchenhao Decoction ameliorates the high-carbohydrate diet induced suppression of immune response in largemouth bass (Micropterus salmoides).cited 16× |
| elimination diet | Decreases - can be effective | inflammation driven by sensitivity to foods | Human | children with EoE not responsive to proton-pump inhibitor (PPI) | Not mentioned | Food avoidance strategies in eosinophilic oesophagitis.cited 31× |
| higher protein diet (2.50 g·kg-1·day-1) | No effect - is not more effective than 1.25 g·kg-1·day-1 for attenuating | indirect markers of muscle damage and inflammation | Human | older adults | 2.50 g·kg⁻¹·day⁻¹ (higher protein) and 1.25 g·kg⁻¹·day⁻¹ (moderate protein). | The Effects of a High-Protein Diet on Markers of Muscle Damage Following Exercise in Active Older Adults: A Randomized, Controlled Trial.cited 1× |
| Groningen anti-inflammatory diet (GrAID) | No effect - aim to investigate the effects | intestinal inflammation | Human | patients with CD | Not specified | Effects of ileocolonic delivered vitamin B2, B3 and C (ColoVit) or the Groningen anti-inflammatory diet on disease course and microbiome of patients with Crohn's disease (VITA-GrAID study): a protocol for a randomised and partially blinded trial.cited 4× |
| Groningen anti-inflammatory diet (GrAID) | No effect - aim to investigate the effects | intestinal inflammation | Human | healthy household members | Not specified | Effects of ileocolonic delivered vitamin B2, B3 and C (ColoVit) or the Groningen anti-inflammatory diet on disease course and microbiome of patients with Crohn's disease (VITA-GrAID study): a protocol for a randomised and partially blinded trial.cited 4× |
| diet | No effect - affects | inflammation | Human | — | 2 portions per week. | Ideal food pyramid for patients with rheumatoid arthritis: A narrative review.cited 29× |
| diet | Increases - can aggravate or attenuate | inflammation | Human | — | Not specified | The Relevance of Selenium Status in Rheumatoid Arthritis.cited 23× |
| diet intervention rich in olive oil | No effect - were not significantly different | inflammation and coagulation marker responses | Human | adults with untreated hypercholesterolemia | Approximately 30% of energy needs from olive oil (monounsaturated fat) for 8 weeks. | No Observed Difference in Inflammatory and Coagulation Markers Following Diets Rich in n-6 Polyunsaturated Fat vs Monounsaturated Fat in Adults With Untreated Hypercholesterolemia: A Randomized Trial.cited 1× |
| diet intervention rich in cottonseed oil | No effect - were not significantly different | inflammation and coagulation marker responses | Human | adults with untreated hypercholesterolemia | Approximately 30% of energy needs from olive oil (monounsaturated fat) for 8 weeks. | No Observed Difference in Inflammatory and Coagulation Markers Following Diets Rich in n-6 Polyunsaturated Fat vs Monounsaturated Fat in Adults With Untreated Hypercholesterolemia: A Randomized Trial.cited 1× |
| diet high in wheat aleurone | No effect - evaluated the effects | plasma antioxidants status, markers of inflammation and endothelial function | Human | seventy-nine healthy, older, overweight participants (45-65 years, BMI>25 kg/m²) | 27 g aleurone per day. | Evaluation of the effect of wheat aleurone-rich foods on markers of antioxidant status, inflammation and endothelial function in apparently healthy men and women.cited 28× |
| low glycemic index (LGI) diet | Decreases - may have favorable effect | inflammation | Human | overweight and obese adolescent girls | Not specified (GI in the LGI group was 43.22±0.54). | The Impact of a Low Glycemic Index Diet on Inflammatory Markers and Serum Adiponectin Concentration in Adolescent Overweight and Obese Girls: A Randomized Clinical Trial.cited 19× |
| Western diet (WD) | Decreases - protected | DSS-induced colonic inflammation | Animal | mice | WD (41.2% energy from fat), LFD (10.3% energy from fat) | A High-Fat Western Diet Attenuates Intestinal Changes in Mice with DSS-Induced Low-Grade Inflammation.cited 8× |
| Western-diet (WD) | Increases - associated with | hepatic inflammation | Animal | female ovariectomized (OVX) ApoE KO mice | Not specified for Western Diet; estradiol dosage not detailed. | Estradiol Protects Female ApoE KO Mice against Western-Diet-Induced Non-Alcoholic Steatohepatitis.cited 6× |
| western diet (WD) | Increases - exacerbated | hepatic inflammation and fibrosis | HumanAnimalMolecular | Rag1 KO mice | Not specified for WD; Treg induction used recombinant IL2/αIL2 mAb cocktail. | Western diet dampens T regulatory cell function to fuel hepatic inflammation in nonalcoholic fatty liver disease.cited 1× |
| Western diet (WD) | Increases - promotes | IL-23-mediated skin and joint inflammation | Animal | mice | Not specified | Western Diet and Psoriatic-Like Skin and Joint Diseases: A Potential Role for the Gut Microbiota.cited 9× |
| diet manipulation | Decreases - mitigated | WD-associated inflammation | Animal | mice | Not specified | Western Diet and Psoriatic-Like Skin and Joint Diseases: A Potential Role for the Gut Microbiota.cited 9× |
| Western diet (WD) | Increases - significantly increased | inflammation | HumanAnimalMolecular | WT mice | Not specified (mice were fed a Western Diet ad libitum for 16 weeks). | Mast Cells Promote Nonalcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed a Western Diet.cited 36× |
| Western diet (WD) | Increases - upregulated | inflammation | Animal | AOM/DSS-induced mouse model | Not specified in the abstract. | Anti-Obesity Drug Orlistat Alleviates Western-Diet-Driven Colitis-Associated Colon Cancer via Inhibition of STAT3 and NF-κB-Mediated Signaling.cited 25× |
| Western diet | Increases - is associated with | inflammation | Human | — | Not specified | Western Diet and Inflammatory Mechanisms in African American Adults With Heart Failure.cited 2× |
| Western diet | Increases - exhibited | numerous markers of NAFLD, including hepatomegaly, lipid accumulation, and inflammation | Animal | mice | Not specified | Hepatic lysosomal acid lipase overexpression worsens hepatic inflammation in mice fed a Western diet.cited 8× |
| Western diet (WD) | Increases - induces | systemic inflammation | Animal | — | Not specified | Intestinal Microbiota Remodeling Protects Mice from Western Diet-Induced Brain Inflammation and Cognitive Decline.cited 18× |
| Western diet (WD) | Increases - contribution to the development of | systemic low-grade inflammation | Human | — | Not specified | The microbiome-driven impact of western diet in the development of noncommunicable chronic disorders.cited 12× |
| Western diet (WD) | Increases - increases in | VCAM-1, MCP-1, TNF-α, and IL-1β for immune cell chemotaxis and inflammation | Animal | ApoE WD group | Not specified (Western diet composition not detailed). | Endurance exercise ameliorates Western diet-induced atherosclerosis through modulation of microbiota and its metabolites.cited 21× |
| HFHC diet | No effect - without the feature of liver inflammation | liver inflammation | Animal | C57BL/6J and DBA/2J mice | Not specified. | Dissociation of hepatic insulin resistance from susceptibility of nonalcoholic fatty liver disease induced by a high-fat and high-carbohydrate diet in mice.cited 31× |
| proposed anti-inflammatory diet | Decreases - likely reduced | systemic inflammation | Human | those who completed the study with high compliance (n = 29) | Not specified (dietary intervention focused on high intake of fatty fish, whole grains, fruits, nuts, and berries). | Proposed Anti-Inflammatory Diet Reduces Inflammation in Compliant, Weight-Stable Patients with Rheumatoid Arthritis in a Randomized Controlled Crossover Trial.cited 18× |
| low-salt diet | No effect - did not differ | Changes in inflammation biomarkers | Human | salt-sensitive and salt-resistant patients | 10-20 mmol sodium diet with sodium tablets (180 mEq/day) to achieve 200 mmol intake per day | Procalcitonin and the inflammatory response to salt in essential hypertension: a randomized cross-over clinical trial.cited 18× |
| maternal Western hypercaloric diet (HCD) programming during the perinatal period | No effect - targeted | hypothalamic genes involved in inflammation and type 2 diabetes | Animal | programmed male offspring | Not specified (dams fed HCD for 1 month pre-mating and throughout pregnancy/lactation; offspring fed HCD or RD for 3 months post-weaning). | Maternal Western diet programs cardiometabolic dysfunction and hypothalamic inflammation via epigenetic mechanisms predominantly in the male offspring.cited 5× |
| high-AGE diet | Increases - increase in inflammation | inflammation | Human | subjects | Not specified | Effect of advanced glycation end product intake on inflammation and aging: a systematic review.cited 81× |
| low-AGE diet | Decreases - decrease in inflammation | inflammation | Human | subjects | Not specified | Effect of advanced glycation end product intake on inflammation and aging: a systematic review.cited 81× |
| high protein diet | Increases - slightly aggravated | IMQ-induced skin inflammation | Animal | male C57BL/6J mice | Not specified (low, regular, high protein chow) | Effects of Dietary Protein Intake on Cutaneous and Systemic Inflammation in Mice with Acute Experimental Psoriasis.cited 4× |
| low crude protein (CP) diet (17%) | No effect - did not negatively impact | inflammation | Animal | 21-day postweaned pigs | Phase 1: Low CP (17%) with 1.4% SID Lys or High CP (24%) with 1.4% SID Lys. Phase 2: Low CP (17%) with 1.35% SID Lys or High CP (24%) with 1.35% SID Lys. | Effects of dietary protein level on intestinal function and inflammation in nursery pigs.cited 2× |
| low crude protein (LCP) diet | Decreases - ameliorated | systemic inflammation induced by USC | Animal | weaned pigs | High CP (22%) and low CP (19%) diets, with varying CAA supplementation (9 or 6 indispensable amino acids). | Effects of dietary protein content and crystalline amino acid supplementation patterns on growth performance, intestinal histomorphology, and immune response in weaned pigs raised under different sanitary conditions.cited 8× |
| high-fat diet consumption | Increases - occur rapidly | hypothalamic inflammation and gliosis | HumanAnimal | rodents | Not specified | Hypothalamic inflammation and gliosis in obesity.cited 104× |
| high-fat diet consumption | Increases - occur prior to significant weight gain | hypothalamic inflammation and gliosis | HumanAnimal | rodents | Not specified | Hypothalamic inflammation and gliosis in obesity.cited 104× |
| diet-induced obesity | Increases - correlates with the presence or absence of | hypothalamic inflammation and reactive gliosis | HumanAnimal | rodents | Not specified | Hypothalamic inflammation and gliosis in obesity.cited 104× |
| ketogenic diet (KD) | Decreases - reducing | inflammation | Human | — | Not specified | Ketogenic diet in treating sepsis-related acquired weakness: is it friend or foe? |
| ketogenic diet | Decreases - could contribute to modulating | inflammation | Human | obese and overweight subjects | Not specified | Does the Ketogenic Diet Mediate Inflammation Markers in Obese and Overweight Adults? A Systematic Review and Meta-Analysis of Randomized Clinical Trials. |
| ketogenic diet (KD) | Decreases - likely by reducing | inflammation and cell death in the spinal cord | Human | SCI rat model | Not specified | Evaluation of a ketogenic diet for improvement of neurological recovery in individuals with acute spinal cord injury: study protocol for a randomized controlled trial.cited 8× |
| ketogenic diet (KD) | No effect - pleiotropic effects on pathophysiology | inflammation and oxidative stress | Animal | — | Not specified | VDAC1 Inhibition Mitigates Inflammatory Status and Oxidative Stress in Epileptic Mice Treated with the Ketogenic Diet. |
| ketogenic diet | Decreases - leading to milder | local non-specific inflammation in the liver | Animal | Sprague-Dawley (SD) rats | Different fat-to-carbohydrate ratios under the same apparent metabolizable energy level (specific amounts not provided) | Generalized Ketogenic Diet Induced Liver Impairment and Reduced Probiotics Abundance of Gut Microbiota in Rat.cited 1× |
| ketogenic diet (KD) | Decreases - plays a variety of roles in controlling | microglia-mediated inflammation | Molecular | — | Not specified | A ketogenic diet regulates microglial activation to treat drug addiction. |
| Omega-3 fatty acid content in the diet and the consumption of their main source, fish | Decreases - may have some regulatory effect | inflammation | Human | patients with lung cancer treated with chemotherapy and radiotherapy | Not specified | Diet as a Factor Supporting Lung Cancer Treatment-A Systematic Review.cited 9× |
| high-salt diet | Increases - exhibit increased | inflammation | Animal | Mice | Not specified | The Gut Microbiome, Inflammation, and Salt-Sensitive Hypertension.cited 52× |
| full-fat dairy diet | No effect - no intervention effects were detected | systemic inflammation | Human | participants with metabolic syndrome | 3.3 servings/day of either low-fat or full-fat dairy. | The impact of diets rich in low-fat or full-fat dairy on glucose tolerance and its determinants: a randomized controlled trial.cited 24× |
| low-fat dairy diet | No effect - no intervention effects were detected | systemic inflammation | Human | participants with metabolic syndrome | 3.3 servings/day of either low-fat or full-fat dairy. | The impact of diets rich in low-fat or full-fat dairy on glucose tolerance and its determinants: a randomized controlled trial.cited 24× |
| gluten-free diet (GFD) | Decreases - normalizes | gut inflammation | Human | celiac disease (CeD) patients | Not specified (gluten-free diet adherence). | Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease.cited 6× |
| gluten-free diet | Increases - plays a key role in NAFLD for consumption of products rich in saturated fats and carbohydrates that promotes accumulation of lipids and lead to | hepatic steatosis and inflammation | Human | — | Not Assessed | The role of gluten-free diet in nonalcoholic fatty liver disease development.cited 4× |
| gluten-free diet | Decreases - improves | muscle inflammation (myositis) component of IIM | Human | patients with idiopathic inflammatory myopathies (IIM) and a concurrent diagnosis of celiac disease (CeD) | Not specified | Small intestinal biopsy findings consistent with celiac disease in patients with idiopathic inflammatory myopathy: Review of existing literature.cited 2× |
| gluten-free diet | Decreases - resolves | symptomatic or asymptomatic inflammation of the small intestinal mucosa | Human | patients with celiac disease | Not specified | Celiac disease.cited 4× |
| gluten-free diet (GFD) | No effect - continue to experience | symptoms and/or persisting intestinal inflammation | Human | up to 30% | Not specified | Non-Responsive Coeliac Disease: A Comprehensive Review from the NHS England National Centre for Refractory Coeliac Disease.cited 54× |
| low-fat (LF) diet | No effect - interacts with | inflammation status | Human | patients with coronary heart disease (CHD) | Not specified | Chronic consumption of a low-fat diet improves cardiometabolic risk factors according to the CLOCK gene in patients with coronary heart disease.cited 31× |
| low-fat diet | Decreases - ameliorated | steatosis, ballooning degeneration and inflammation | Animal | male SD rats with NAFLD | Not specified (dietary intervention only). | Effects of a low-fat diet on the hepatic expression of adiponectin and its receptors in rats with NAFLD.cited 12× |
| exercise + diet | No effect - does not affect | airway inflammation | Human | nonobese adult patients with asthma | — | Effects of Exercise and Diet in Nonobese Asthma Patients-A Randomized Controlled Trial.cited 62× |
| High-caloric diet | Increases - increased | inflammation (p38 mitogen-activated protein kinase) | Animal | male Wistar rats | 60 mg/kg/day (containing 12.48% aspalathin). | Cardioprotective Function of Green Rooibos (Aspalathus linearis) Extract Supplementation in Ex Vivo Ischemic Prediabetic Rat Hearts.cited 4× |
| guar gum containing diet (GuD) | Increases - increased the susceptibility to | colonic inflammation | Animal | mice | Not specified | Dietary fiber guar gum-induced shift in gut microbiota metabolism and intestinal immune activity enhances susceptibility to colonic inflammation.cited 13× |
| a diet rich in n-3 fatty acids | Decreases - may play a role in preventing and reducing | inflammation | Human | healthy adults | Not specified | N-3 polyunsaturated fatty acids: relationship to inflammation in healthy adults and adults exhibiting features of metabolic syndrome.cited 49× |
| diet-induced obesity | Increases - associated with | hypothalamic inflammation | Human | — | Not specified | Is human obesity an inflammatory disease of the hypothalamus?cited 17× |
| privative diet | Decreases - better control | inflammation | Human | RA patients under stable optimized drug treatment | Not specified (dietary intervention). | Improvement of Inflammation and Pain after Three Months' Exclusion Diet in Rheumatoid Arthritis Patients.cited 32× |
| combined high-protein diet and exercise intervention | Decreases - improved | inflammation | Human | middle-aged adults with obesity | Not specified | Effects of Combined High-Protein Diet and Exercise Intervention on Cardiometabolic Health in Middle-Aged Obese Adults: A Randomized Controlled Trial.cited 7× |
| high-fat high-fructose diet (HFHFD) | Decreases - provoked disruptions | expression of proteins regulating food intake, the endocannabinoid system, the insulin pathway, and inflammation | Animal | rats | Not specified | A Combined GLP-1/PPARa/CB1-Based Therapy to Restore the Central and Peripheral Metabolic Dysregulation Induced by a High-Fructose High-Fat Diet. |
| high-fat-fructose-diet (HFFD) | Increases - induced | inflammation | Animal | rats | 55 mg/kg/day, orally. | Raspberry ketone improves non-alcoholic fatty liver disease induced in rats by modulating sphingosine kinase/sphingosine-1-phosphate and toll-like receptor 4 pathways.cited 1× |
| calorie-restricted diet (CR) | Decreases - reversed | inflammation | Animal | rats | 55 mg/kg/day, orally. | Raspberry ketone improves non-alcoholic fatty liver disease induced in rats by modulating sphingosine kinase/sphingosine-1-phosphate and toll-like receptor 4 pathways.cited 1× |
| Western diet-induced oxidative stress | Increases - leading to a marked increase | inflammation and vascular dysfunction | Animal | — | Not specified | Dietary Approaches to Stop Hypertension via Indo-Mediterranean Foods, May Be Superior to DASH Diet Intervention.cited 7× |
| FAWGT diet | Increases - induces beneficial changes on the genes involved in inflammation and oxidative stress | genes involved in inflammation and oxidative stress | Human | obese people | Not specified (diet-based intervention) | Effect of 8-Week Consumption of a Dietary Pattern Based on Fruit, Avocado, Whole Grains, and Trout on Postprandial Inflammatory and Oxidative Stress Gene Expression in Obese People.cited 4× |
| an oral health optimized diet low in carbohydrates, rich in Omega-3 fatty acids, and rich in vitamins C and D, antioxidants and fiber | Decreases - significantly reduced | gingival and periodontal inflammation | Human | — | Not specified (dietary intake, not isolated supplement). | An oral health optimized diet can reduce gingival and periodontal inflammation in humans - a randomized controlled pilot study.cited 124× |
| citrate-enhanced diet | Increases - causes | further liver inflammation and injury | Animal | mice | 67 mg g-1 diet | Citrate enrichment in a Western diet reduces weight gain via browning of adipose tissues without resolving diet-induced insulin resistance in mice.cited 5× |
| optimum diet therapy in the elderly | Decreases - for avoiding | vitamin E deficiency and its negative correlates, such as high inflammation and oxidation | Human | elderly | Not specified | Focus on Pivotal Role of Dietary Intake (Diet and Supplement) and Blood Levels of Tocopherols and Tocotrienols in Obtaining Successful Aging.cited 21× |
| Healthy Nordic diet | Affects - had a beneficial effect on | low-grade inflammation | Human | people with metabolic syndrome | Low-fat dairy products included as part of the diet (specific amounts not detailed). | Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome -- a randomized study (SYSDIET).cited 187× |
| VLCK diet supplemented with DHA | No effect - was tested against | classic cardiovascular risk factors, adipokine levels, and inflammation-resolving eicosanoids | Human | obese patients | Not specified | Effect of DHA supplementation in a very low-calorie ketogenic diet in the treatment of obesity: a randomized clinical trial.cited 43× |
| a diet rich in non-digestible carbohydrates | Decreases - alleviation | inflammation | Animal | PWS (n=17) and simple obesity (n=21) children | Not specified | Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children.cited 272× |
| a proper diet | Decreases - is also able to reduce | inflammation and oxidative stress | Human | — | Not specified | The Influence of Lifestyle and Treatment on Oxidative Stress and Inflammation in Diabetes.cited 60× |
| CIA and an HD diet | Increases - induced a distinct and independent expression of | large-vessel inflammation markers | Animal | B6 mice | — | Aortic VCAM-1: an early marker of vascular inflammation in collagen-induced arthritis. |
| Germinated brown rice (GBR) diet | Decreases - retarded patient inflammation | inflammation | Human | T2DM patients | 100 g/d GBR | Germinated Brown rice enhanced n-3 PUFA metabolism in type 2 diabetes patients: A randomized controlled trial.cited 2× |
| Germinated brown rice (GBR) diet | Decreases - decreased | mean dietary inflammation index (DII) | Human | T2DM patients | 100 g/d GBR | Germinated Brown rice enhanced n-3 PUFA metabolism in type 2 diabetes patients: A randomized controlled trial.cited 2× |
| Adding prebiotics to the diet | Decreases - may reduce | inflammation | Human | — | Not specified | Influence of diet on gut microbiota, inflammation and type 2 diabetes mellitus. First experience with macrobiotic Ma-Pi 2 diet.cited 50× |
| Adherence to cardioprotective dietary patterns, such as the Mediterranean diet (MedDiet) | No effect - has been associated with altered methylation and expression | genes related to inflammation and immuno-competence | HumanMolecular | — | Not specified | Nutriepigenetics and cardiovascular disease.cited 33× |
| surplus of macronutrients such as in a high-fat diet | No effect - can affect | inflammation | HumanMolecular | — | Not specified | Nutriepigenetics and cardiovascular disease.cited 33× |
| maternal Western diet (WD) | Increases - aggravated | inflammation | Human | male offspring | — | Mitochondrial dysfunction characterises the multigenerational effects of maternal obesity on MASLD. |
| low-glycemic index diet and exercise | Decreases - has antiinflammatory and antidiabetogenic effects | inflammation and hyperglycemia | Human | older, obese prediabetics | Low-glycemic-index diet (LGI = 40) and aerobic exercise (5 days/week, 60 min/day, 80-85% heart rate max). | A low-glycemic index diet and exercise intervention reduces TNF(alpha) in isolated mononuclear cells of older, obese adults.cited 59× |
| fast food diet (FFD) | No effect - lobular inflammation was not significantly different | lobular inflammation | Animal | C57BL/6 J mice | Not specified (fast food diet composition not detailed). | Partial validation of a six-month high-fat diet and fructose-glucose drink combination as a mouse model of nonalcoholic fatty liver disease.cited 3× |
| specific carbohydrate diet (SCD) | Decreases - may improve | biochemical markers of inflammation | Human | — | Not specified | Diet as Adjunctive Treatment for Inflammatory Bowel Disease: Review and Update of the Latest Literature.cited 42× |
| specific carbohydrate diet (SCD) | No effect - did not consistently improve | inflammation | Human | patients aged 7-18 years with IBD and active inflammation | Not specified | Personalized Research on Diet in Ulcerative Colitis and Crohn's Disease: A Series of N-of-1 Diet Trials.cited 21× |
| specific carbohydrate diet (SCD) | Decreases - provide the first promising results | inflammation in patients with CD | Human | patients with CD | Not specified | Nutritional interventions for the treatment of IBD: current evidence and controversies.cited 36× |
| CD exclusion diet (CDED) | Decreases - provide the first promising results | inflammation in patients with CD | Human | patients with CD | Not specified | Nutritional interventions for the treatment of IBD: current evidence and controversies.cited 36× |
| specific carbohydrate diet (SCD) | Decreases - showed resolution | prior jejunal inflammation | Human | adult male with complicated Crohn's disease | Not specified | Clinical and Histologic Remission in an Adult Crohn's Disease Patient Following the Specific Carbohydrate Diet and Its Impact on Healthcare Costs.cited 2× |
| HSF/HC diet | Increases - caused the development of | inflammation | Animal | BALB/c male mice | 9% and 17% DTP supplementation in diet | Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets.cited 16× |
| Western diet consumption | Increases - links with | intestinal inflammation | Animal | — | Not specified (high-fat content and sugary drinks implied). | Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation.cited 9× |
| long-term intake of a Western diet (WD) | Increases - showed marked TAS1R3 overexpression with hallmarks of serious | bowel inflammation | Animal | WD-fed mice | Not specified (high-fat content and sugary drinks implied). | Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation.cited 9× |
| Western diet (HFWD)-consumption | Increases - increases susceptibility | silica-induced pulmonary inflammation and fibrosis | Animal | — | Not specified (HFWD composition not detailed) | High-fat Western diet alters crystalline silica-induced airway epithelium ion transport but not airway smooth muscle reactivity.cited 1× |
| HFSS diet | Decreases - reduced | inflammation-resolving Arg-1+ microglia | HumanAnimal | C57BL/6 mice during aging | Not specified | A high fat, sugar, and salt Western diet induces motor-muscular and sensory dysfunctions and neurodegeneration in mice during aging: Ameliorative action of metformin.cited 14× |
| low-cholesterol/low-fat diet (LCLFD) | Decreases - mediate | inflammation reduction | HumanAnimalMolecular | patients | Not specified | Nanoparticle-based itaconate treatment recapitulates low-cholesterol/low-fat diet-induced atherosclerotic plaque resolution.cited 2× |
| paternal high fat (HF) diet | Increases - had higher levels of | markers of inflammation | Animal | male offspring | Not specified | Fishing for Solutions: How Pre-Conceptional Fish Oil Supplementation in Obese Fathers Reduces Risk of Non-Alcoholic Fatty Liver Disease in Offspring Mice.cited 1× |
| high-carbohydrate, high-fat diet including condensed milk (39.5%), beef tallow (20%), and fructose (17.5%) together with 25% fructose in drinking water | Increases | inflammation in the kidneys | Animal | male Wistar rats (8-9 weeks old) | Diet composition: 39.5% condensed milk, 20% beef tallow, 17.5% fructose, plus 25% fructose in drinking water | High-carbohydrate high-fat diet–induced metabolic syndrome and cardiovascular remodeling in rats.cited 259× |
| high-carbohydrate, high-fat diet including condensed milk (39.5%), beef tallow (20%), and fructose (17.5%) together with 25% fructose in drinking water | Increases | inflammation in the left ventricle of the heart | Animal | male Wistar rats (8-9 weeks old) | Diet composition: 39.5% condensed milk, 20% beef tallow, 17.5% fructose, plus 25% fructose in drinking water | High-carbohydrate high-fat diet–induced metabolic syndrome and cardiovascular remodeling in rats.cited 259× |
| high-carbohydrate, high-fat diet including condensed milk (39.5%), beef tallow (20%), and fructose (17.5%) together with 25% fructose in drinking water | Increases | inflammation in the liver | Animal | male Wistar rats (8-9 weeks old) | Diet composition: 39.5% condensed milk, 20% beef tallow, 17.5% fructose, plus 25% fructose in drinking water | High-carbohydrate high-fat diet–induced metabolic syndrome and cardiovascular remodeling in rats.cited 259× |
| high-fat diet (HFD) feeding | Increases - exacerbated | secondary inflammation | Animal | CIA rats | — | Non-alcoholic fatty liver disease combined with rheumatoid arthritis exacerbates liver fibrosis by stimulating co-localization of PTRF and TLR4 in rats. |
| DHA-diet supplementation | Decreases - evidencing anti-inflammatory effects of DHA to control inflammation | inflammation after acute exercise | Human | well-trained footballers | 1.14 g per day. | Effect of DHA on plasma fatty acid availability and oxidative stress during training season and football exercise.cited 26× |
| DASH diet | Decreases - can play an important role in reducing | inflammation | Human | diabetic patients | Not specified (DASH diet included low-fat dairy as part of a broader dietary pattern) | The Dietary Approaches to Stop Hypertension eating plan affects C-reactive protein, coagulation abnormalities, and hepatic function tests among type 2 diabetic patients.cited 141× |
| Mediterranean diet combined with the ketogenic diet | Decreases - therapeutic interventions specifically aimed at reducing | levels of inflammation and oxidative stress | Human | — | Not specified | The role of high-density lipoprotein cholesterol, apolipoprotein A and paraoxonase-1 in the pathophysiology of neuroprogressive disorders.cited 39× |
| Mediterranean diet | Decreases - therapeutic interventions specifically aimed at reducing | levels of inflammation and oxidative stress | Human | — | Not specified | The role of high-density lipoprotein cholesterol, apolipoprotein A and paraoxonase-1 in the pathophysiology of neuroprogressive disorders.cited 39× |
| high-fat/low-fiber 'Western-type' diet (WD) | No effect - not of | increased inflammation | Animal | mice | Not specified (diet composition described as "high-fat/low-fiber" and "low-fat/low-fiber"). | Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice.cited 14× |
| plant-based diet | Decreases - reducing | inflammation | Human | IBD patients | Not specified | The role of a plant-based diet in the pathogenesis, etiology and management of the inflammatory bowel diseases.cited 23× |
| plant-based diet (PBD) | Decreases - recognized as anti-inflammatory | inflammation | Human | — | Not specified | Incorporation of Plant-Based Diet Surpasses Current Standards in Therapeutic Outcomes in Inflammatory Bowel Disease.cited 6× |
| plant-based diet | Decreases - decreased | intestinal inflammation | Human | CD patients | Not specified (dietary intervention). | Modulating the gut microbiota in Crohn's disease: a pilot study on the impact of a plant-based diet with DNA-based monitoring. |
| diet rich in RS fiber | Decreases - reduced | inflammation | Animal | spontaneously hypertensive rats (SHR) | Not specified | Protective Effect of Dietary Fiber on Blood Pressure and Vascular Dysfunction Through Regulation of Sympathetic Tone and Immune Response in Genetic Hypertension. |
| A 5-day, CSO-enriched diet | Decreases - may be sufficient to reduce | inflammation and coagulation potential | Human | healthy male population | 44% of total energy from oil (either CSO or OO). | Improvements in markers of inflammation and coagulation potential following a 5-day high-fat diet rich in cottonseed oil vs. Olive oil in healthy males.cited 2× |
| VCO-supplemented diet | Decreases - inhibiting its mechanisms of toxicity that are related to | inflammation | Animal | adult male rats | 5% and 15% VCO | Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway.cited 5× |
| regular diet | Decreases - partially alleviated | inflammation in perirenal and epididymal fat tissues | Animal | obese mice | Not specified (daily oral administration via gavage). | Evaluation of a Standard Dietary Regimen Combined with Heat-Inactivated Lactobacillus gasseri HM1, Lactoferrin-Producing HM1, and Their Sonication-Inactivated Variants in the Management of Metabolic Disorders in an Obesity Mouse Model.cited 3× |
| consuming a healthy, plant-based diet | Decreases - can reduce | skin inflammation | Human | — | Not specified | Nutritional and Microbial Strategies for Treating Acne, Alopecia, and Atopic Dermatitis.cited 2× |
| A diet supplemented with vitamin D and marine omega-3 fatty acids | Increases - promoting | the resolution of inflammation | Human | — | 2000 IU/day of vitamin D | The effect of vitamin D and omega-3 fatty acid supplementation on pain prevalence and severity in older adults: a large-scale ancillary study of the VITamin D and OmegA-3 triaL (VITAL).cited 5× |
| high-fat diet and alcohol | Increases - showed chronic | inflammation | Animal | animals | Not specified | Effect of a high-fat diet and alcohol on cutaneous repair: A systematic review of murine experimental models.cited 8× |
| healthy diet | Decreases - can decrease | inflammation | Human | — | Not specified | Dietary pattern in relation to the risk of Alzheimer's disease: a systematic review.cited 55× |
| Mediterranean diet (Med Diet) | Decreases - has potential to modulate | chronic low-grade inflammation (LGI) | Human | various diseases | Not specified | Nutritional interventions as modulators of the disease activity for idiopathic inflammatory myopathies: a scoping review. |
| Mediterranean diet | Decreases - has been shown to have strong anti-inflammatory effects | inflammation | Human | — | Not specified | Total urinary polyphenol excretion: a biomarker of an anti-inflammatory diet and metabolic syndrome status.cited 3× |
| Mediterranean diet (MD) | Decreases - effective in reducing | inflammation | Human | patients with mild-to-moderate active ulcerative colitis (UC) | 1600 mg/day of curcumin supplementation. | Effects of Mediterranean Diet, Curcumin, and Resveratrol on Mild-to-Moderate Active Ulcerative Colitis: A Multicenter Randomized Clinical Trial.cited 4× |
| Mediterranean diet | Decreases - effectiveness lies in its anti-inflammatory power | inflammation | Human | patients with psoriasis | Not specified | Metabolic Disorders and Psoriasis: Exploring the Role of Nutritional Interventions.cited 11× |
| Mediterranean Diet (MedDiet) | Decreases - anti-inflammatory effect | inflammation | Human | — | Not specified | MicroRNAs and the Mediterranean diet: a nutri-omics perspective for lung cancer.cited 4× |
| Mediterranean diet | Decreases - reduce | inflammation | Human | — | Not specified | Mediterranean diet and osteoarthritis: an update.cited 2× |
| Mediterranean diet (MedDiet) | Decreases - anti-inflammatory properties | inflammation | Human | — | 500 mL of extra virgin olive oil per week, along with dietary education sessions. | Impact of the Mediterranean Diet on Patients With Psoriasis: Protocol for a Randomized Controlled Trial.cited 1× |
| Mediterranean Diet | Decreases - decreased | markers of inflammation | Human | — | Not specified | Impact of the Mediterranean Diet on Athletic Performance, Muscle Strength, Body Composition, and Antioxidant Markers in Both Athletes and Non-Professional Athletes: A Systematic Review of Intervention Trials.cited 3× |
| Mediterranean diet (MD) | Decreases - may also decrease | several biomarkers of inflammation | Human | — | Not specified | The Mediterranean Diet and Cardiovascular Disease: Gaps in the Evidence and Research Challenges.cited 18× |
| Long-term supplementation of Ozonated sunflower oil (OSO) (final 20%, wt/wt) with high-cholesterol diet (HCD) for 6 months | Decreases - showed the least | hepatic inflammation | Animal | adult hypercholesterolemic zebrafish | Microinjection (final 2%, 10 nL); dietary supplementation (final 20%, wt/wt). | Long-Term Supplementation of Ozonated Sunflower Oil Improves Dyslipidemia and Hepatic Inflammation in Hyperlipidemic Zebrafish: Suppression of Oxidative Stress and Inflammation against Carboxymethyllysine Toxicity.cited 14× |
| overall adherence to the Mediterranean Diet | No effect - No association | inflammation | Human | women with SLE with mild disease activity | Not specified | Association of the Mediterranean diet with arterial stiffness, inflammation, and medication use in women with systemic lupus erythematosus: An exploratory study.cited 2× |
| HFHS-R diet | Decreases - significantly decreased | visceral adipocyte hypertrophy and adipose tissue inflammation | HumanAnimalMolecular | C57BL/6 male mice | Equivalent to 0.03% of EA from raspberry seed flour. | Raspberry seed flour attenuates high-sucrose diet-mediated hepatic stress and adipose tissue inflammation.cited 37× |
| Key components of the Mediterranean diet (MD)-including microbiota-accessible carbohydrates, omega-3 fatty acids, polyphenols, and antioxidants | Decreases - have demonstrated promise in reducing | intestinal inflammation | Human | — | Not specified | From Evidence to Practice: A Narrative Framework for Integrating the Mediterranean Diet into Inflammatory Bowel Disease Management.cited 1× |
| high-fat diet with a large amount of long-chain saturated fatty acids | Increases - can induce | inflammation in the hypothalamus | Human | — | Not specified | Hypothalamic Inflammation as a Potential Pathophysiologic Basis for the Heterogeneity of Clinical, Hormonal, and Metabolic Presentation in PCOS.cited 20× |
| low adherence to the Mediterranean diet | Decreases - display unfavorable profiles of | circulating markers of redox balance and inflammation | Human | old patients admitted to internal medicine wards | Not specified | Adherence to Mediterranean Diet and Biomarkers of Redox Balance and Inflammation in Old Patients Hospitalized in Internal Medicine.cited 1× |
| low adherence to the Mediterranean diet | Increases - higher | markers of systemic inflammation | Human | old patients hospitalized in internal medicine wards | Not specified | Adherence to Mediterranean Diet and Biomarkers of Redox Balance and Inflammation in Old Patients Hospitalized in Internal Medicine.cited 1× |
| Mediterranean-styled Japanese diet | Decreases - reduces the risk of various diseases by suppressing | chronic inflammation | Human | — | Not specified | The Recommendation of the Mediterranean-styled Japanese Diet for Healthy Longevity.cited 3× |
| MIND diet | Decreases - associated with an improvement | inflammation | Human | adults | Not specified | Associations of the MIND Diet with Cardiometabolic Diseases and Their Risk Factors: A Systematic Review.cited 13× |
| glutamine-supplemented diet | Decreases - significant reduction | inflammation levels | AnimalMolecular | 3-month COPD murine model | Not specified | METTL16 controls airway inflammations in smoking-induced COPD via regulating glutamine metabolism. |
| high fat diet alone | Increases - produces | obesity, insulin resistance, and some degree of fatty liver with minimal inflammation and no fibrosis | HumanAnimal | — | Not specified for high-fat diet; high-fructose corn syrup amounts relevant to American consumption levels. | Fructose as a key player in the development of fatty liver disease.cited 160× |
| High-oat bran diet | Decreases - reduces the intensity | radiation-induced inflammation | Animal | mice | 15% fiber (high-oat bran diet). | Dietary Oat Bran Reduces Systemic Inflammation in Mice Subjected to Pelvic Irradiation.cited 12× |
| low carbohydrate diet (LCD) | Decreases - reduction in | inflammation | Human | — | Not specified | Low carbohydrate diet: are concerns with saturated fat, lipids, and cardiovascular disease risk justified?cited 19× |
| Low carbohydrate diet (LCD) | Decreases - can improve | inflammation | Human | overweight and obese women | Not specified. | Circulating inflammatory markers may mediate the relationship between low carbohydrate diet and circadian rhythm in overweight and obese women.cited 9× |
| A diet low in n-3 polyunsaturated fatty acids | Decreases - induce a reduction in the GRP120 signal and the activation of Kupffer cells and inflammation | GRP120 signal, activation of Kupffer cells, inflammation | Human | during NAFLD | Not specified | Docosahexaenoic Acid and Its Role in G-Protein-Coupled Receptor 120 Activation in Children Affected by Nonalcoholic Fatty Liver Disease.cited 8× |
| low FODMAP diet | Decreases - might decrease | systemic and intestinal inflammation | Human | patients with ulcerative colitis | Not specified | A randomized controlled trial investigating the effect of a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols on the intestinal microbiome and inflammation in patients with ulcerative colitis: study protocol for a randomized controlled trial.cited 13× |
| following a ketogenic diet | Decreases - investigated the role in reducing | inflammation | Human | clinical trials | Not provided | Nutrition in chronic inflammatory conditions: Bypassing the mucosal block for micronutrients.cited 23× |
| high fat and carbonated soda (HFD/soda) diet | Increases - increased the effects of | inflammation | Animal | Wistar rats | Not specified. | Oxidative stress and inflammatory response to high dietary fat and carbonated soda intake in male and female Wistar rats.cited 5× |