Modified Mediterranean diet
Study Goal
The researchers aimed to investigate whether a modified Mediterranean diet (mMeD) could improve dietary inflammatory status, disability, and fatigue severity in relapsing-remitting multiple sclerosis (RRMS) patients compared to a traditional Iranian diet (TID).
Results Summary
The study found that adherence to mMeD for 6 months improved dietary inflammatory status and fatigue severity in RRMS patients, while the TID did not show positive effects on dietary inflammation or fatigue.
Population
Relapsing-remitting multiple sclerosis (RRMS) patients (n=147).
Effective Dosage
Not specified
Duration
6 months
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
modified Mediterranean diet (mMeD) | decrease | dietary inflammatory status | RRMS patients | - | improved | #1 |
modified Mediterranean diet (mMeD) | decrease | fatigue severity | RRMS patients | - | improved | #2 |
traditional Iranian diet (TID) | no change | dietary inflammation | RRMS patients | - | did not positively impact | #3 |
traditional Iranian diet (TID) | no change | MFIS score | RRMS patients | - | did not positively impact | #4 |
BACKGROUND: Current evidence suggests that adherence to the Mediterranean diet (MeD) can reduce inflammation in chronic diseases; however, studies pertaining to relapsing-remitting multiple sclerosis (RRMS) are limited. Therefore, the aim of this study was to investigate the potential of the modified MeD (mMeD) in improving Dietary Inflammatory Index (DII) scores, disability and fatigue severity, compared with traditional Iranian diet (TID), in RRMS patients. RESULTS: Of the 180 patients enrolled, 147 participants were included in the final analysis (n of mMeD = 68; METHODS: After initial screening ( CONCLUSION: Adherence to mMeD, for 6 months, improved dietary inflammatory status and fatigue severity in RRMS patients; however, the TID did not positively impact dietary inflammation and MFIS score.