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Evidence suggests Ketogenic Diet maydecreaseAnxiety symptoms.
49 studies (68 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| personalized Mediterranean diet plans delivered via a clinical decision support system | Decreases - improved | anxiety | Human | adolescent females with polycystic ovary syndrome | Personalized MD plans delivered every 15 days via CDSS (specific dietary amounts not detailed). | Optimizing Dietary Habits in Adolescents with Polycystic Ovary Syndrome: Personalized Mediterranean Diet Intervention via Clinical Decision Support System-A Randomized Controlled Trial.cited 2× |
| vegetarian diet | Increases - displayed elevated prevalence rates | anxiety disorders | Human | participants from the German Health Interview and Examination Survey and its Mental Health Supplement | Not specified | Vegetarian diet and mental disorders: results from a representative community survey.cited 72× |
| low-FODMAP diet plus a probiotic supplement (Lactobacillus rhamnosus) | Decreases - decreased significantly | anxiety scores | Human | female IBS patients between the ages of 20 and 55 | Not specified (probiotic strain: Lactobacillus rhamnosus). | Evaluation of the effects of the FODMAP diet and probiotics on irritable bowel syndrome (IBS) symptoms, quality of life and depression in women with IBS.cited 5× |
| low-FODMAP diet | Decreases - decreased significantly | anxiety scores | Human | female IBS patients between the ages of 20 and 55 | Not specified (probiotic strain: Lactobacillus rhamnosus). | Evaluation of the effects of the FODMAP diet and probiotics on irritable bowel syndrome (IBS) symptoms, quality of life and depression in women with IBS.cited 5× |
| AKG-supplemented diet | Increases - had a proclivity to promote | anxiety-like behavior | Animal | mice | Not specified | High-fat high-fructose diet and alpha-ketoglutarate affect mouse behavior that is accompanied by changes in oxidative stress response and energy metabolism in the cerebral cortex.cited 3× |
| low-carbohydrate diet (LCD) without exercise training | No effect - no statistical differences | anxiety | Human | overweight Chinese women | ~50 g daily carbohydrate intake. | Effect of a Low-Carbohydrate Diet With or Without Exercise on Anxiety and Eating Behavior and Associated Changes in Cardiometabolic Health in Overweight Young Women.cited 4× |
| low-carbohydrate diet (LCD) with exercise training | Decreases - significant improvements | anxiety | Human | overweight Chinese women | ~50 g daily carbohydrate intake. | Effect of a Low-Carbohydrate Diet With or Without Exercise on Anxiety and Eating Behavior and Associated Changes in Cardiometabolic Health in Overweight Young Women.cited 4× |
| low-carbohydrate diet (LCD) with exercise training | Decreases - significant reductions | anxiety levels | Human | overweight Chinese women | ~50 g daily carbohydrate intake. | Effect of a Low-Carbohydrate Diet With or Without Exercise on Anxiety and Eating Behavior and Associated Changes in Cardiometabolic Health in Overweight Young Women.cited 4× |
| low-carbohydrate diet (LCD) with exercise training | Decreases - negative association | levels of anxiety and V̇O2peak | Human | all participates | ~50 g daily carbohydrate intake. | Effect of a Low-Carbohydrate Diet With or Without Exercise on Anxiety and Eating Behavior and Associated Changes in Cardiometabolic Health in Overweight Young Women.cited 4× |
| low-calorie diet with increased protein percentage | Decreases - had significantly lower | depression and anxiety scores | Human | obese individuals | Not specified (only mentions "increased protein percentage" without exact amounts). | The effect of a low-calorie, high-protein diet on psychometric variables in obese individuals: a Randomized Clinical Trial.cited 2× |
| low-calorie diet with increased protein percentage | Decreases - significant differences were observed | depression, stress, and anxiety | Human | obese individuals | Not specified (only mentions "increased protein percentage" without exact amounts). | The effect of a low-calorie, high-protein diet on psychometric variables in obese individuals: a Randomized Clinical Trial.cited 2× |
| energy-restricted diet (control group) | No effect - did not change | anxiety symptoms | Human | overweight or obese middle-aged subjects | 1.4 g cocoa extract/day (645 mg total polyphenols/day). | An Increase in Plasma Homovanillic Acid with Cocoa Extract Consumption Is Associated with the Alleviation of Depressive Symptoms in Overweight or Obese Adults on an Energy Restricted Diet in a Randomized Controlled Trial.cited 20× |
| cocoa extract supplementation as part of an energy-restricted diet | No effect - did not change | anxiety symptoms | Human | overweight or obese middle-aged subjects | 1.4 g cocoa extract/day (645 mg total polyphenols/day). | An Increase in Plasma Homovanillic Acid with Cocoa Extract Consumption Is Associated with the Alleviation of Depressive Symptoms in Overweight or Obese Adults on an Energy Restricted Diet in a Randomized Controlled Trial.cited 20× |
| Diet enriched with alpha-lactalbumin (alpha-lac) | Decreases - exhibited anxiolytic and antidepressive activities | anxiety and depression-like status | Animal | male C57BL/6J mice | 17% (w/w) of the experimental diet. | The effects of native whey and α-lactalbumin on the social and individual behaviour of C57BL/6J mice.cited 14× |
| low calorie MIND diet | Decreases - significantly reduced | anxiety scores | Human | women with PCOS | Not specified (low-calorie MIND diet). | The effects of MIND diet on depression, anxiety, quality of life and metabolic and hormonal status in obese or overweight women with polycystic ovary syndrome: a randomised clinical trial.cited 3× |
| high-fat diet (HFD) | Increases - aggravates | anxiety and depression-like behaviors and learning and memory deficits induced by CRS | AnimalMolecular | Male C57BL/6 mice | Not specified (8-week high-fat diet intervention). | High-fat diet and chronic restraint stress exacerbate anxiety-depressive behaviors via astrocytic A1 phenotype transformation. |
| high fat diet (HFD) | Increases - induced | anxiety-like behavior in the open field test (OFT) | Animal | rats | — | Agomelatine effects on fat-enriched diet induced neuroinflammation and depression-like behavior in rats. |
| high-fat diet (HFD) | Increases - showed | anxiety-like behaviors | Animal | ICR male mice | 0.5% GORZ in diet. | Gamma Oryzanol Alleviates High-Fat Diet-Induced Anxiety-Like Behaviors Through Downregulation of Dopamine and Inflammation in the Amygdala of Mice.cited 16× |
| high-fat diet | Increases - higher levels of anxiety | anxiety symptoms or disorder prevalence | Human | — | Not specified | Diet and Anxiety: A Scoping Review.cited 92× |
| ketogenic diet | Decreases - less anxiety | anxiety symptoms or disorder prevalence | Human | — | Not specified | Diet and Anxiety: A Scoping Review.cited 92× |
| a 12-week brisk walking and diet education program | Increases - improved | anxiety | Human | patients with esophageal cancer | Brisk walking (specific frequency/intensity not detailed) and diet education. | Effects of Rehabilitation Program on Quality of Life, Sleep, Rest-Activity Rhythms, Anxiety, and Depression of Patients With Esophageal Cancer: A Pilot Randomized Controlled Trial.cited 8× |
| a rehabilitation program comprising exercise and diet education | Decreases - alleviate | anxiety | Human | patients with esophageal cancer | Brisk walking (specific frequency/intensity not detailed) and diet education. | Effects of Rehabilitation Program on Quality of Life, Sleep, Rest-Activity Rhythms, Anxiety, and Depression of Patients With Esophageal Cancer: A Pilot Randomized Controlled Trial.cited 8× |
| low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet | No effect - no differences were recorded | clinical anxiety | Human | IBS patients | Not specified | Group education on the low FODMAP diet improves gastrointestinal symptoms but neither anxiety or depression in irritable bowel syndrome.cited 17× |
| a modified ketogenic diet | Decreases - inverse correlation | anxiety | Human | participants providing reliable daily ecological momentary assessment data | Not specified (modified ketogenic diet). | A pilot study of a ketogenic diet in bipolar disorder: clinical, metabolic and magnetic resonance spectroscopy findings.cited 1× |
| maternal High-Fat Diet (HFD) intake during gestation and lactation | Increases - reported as increased | anxiety-like behavior | Human | offspring | Not specified | Neurobiological approaches of high-fat diet intake in early development and their impact on mood disorders in adulthood: A systematic review.cited 9× |
| MIND diet score | Decreases - significant reverse linear association | anxiety disorders | Human | patients with anxiety disorders and healthy subjects | Not specified | Adherence to the MIND diet is inversely associated with odds and severity of anxiety disorders: a case-control study.cited 15× |
| MIND diet | Decreases - were 97% less likely to have | anxiety disorders | Human | Individuals in the top category of MIND diet score compared with those in the bottom category | Not specified | Adherence to the MIND diet is inversely associated with odds and severity of anxiety disorders: a case-control study.cited 15× |
| beta-alanine-supplemented diet (22.5 mmol/kg diet) | Decreases - had an anxiolytic-like effect | anxiety-like behavior | Animal | mice | 22.5 mmol/kg diet | The impact of taurine- and beta-alanine-supplemented diets on behavioral and neurochemical parameters in mice: antidepressant versus anxiolytic-like effects.cited 69× |
| diet | Decreases - may play a role in the management | anxiety and fear | Human | cancer survivors | Not specified | Integrative medicine in cancer survivors.cited 27× |
| chronic consumption of a high-refined carbohydrate (HC) diet | Increases - observed | compulsive-like and anxiety-like behaviors | Animal | mice | 30 mg/kg, intraperitoneal administration | Cannabidiol ameliorates the anxiogenic and compulsive-like behaviors induced by chronic consumption of a high-carbohydrate diet in male mice.cited 1× |
| Wahls diet | Decreases - Significant improvement | severity of anxiety (HADS-A) symptoms | Human | participants with RRMS | Not specified | Association of serum homocysteine, folate, and vitamin Bcited 6× |
| Swank diet | Decreases - Significant improvement | severity of anxiety (HADS-A) symptoms | Human | participants with RRMS | Not specified | Association of serum homocysteine, folate, and vitamin Bcited 6× |
| high-fat diet (HFD) consumption throughout adolescence | Increases - developed | anxiety-like behaviours | Animal | mice | Not specified | Minocycline treatment attenuates neurobehavioural abnormalities and neurostructural aberrations in the medial prefrontal cortex in mice fed a high-fat diet during adolescence. |
| Mediterranean diet intervention | Decreases - significantly lower | anxiety scores | Human | high-risk pregnant women | Not specified | Effects of a Mediterranean Diet Intervention on Maternal Stress, Well-Being, and Sleep Quality throughout Gestation-The IMPACT-BCN Trial.cited 7× |
| ketogenic diet | Increases - improvements in | anxiety symptoms | Human | — | Not specified | Measuring the effects of ketogenic diet on neuropsychiatric disorder: A scoping review. |
| ketogenic diet | Increases - suggesting that it may provide therapeutic effects for | several psychiatric conditions such as mood- and anxiety-related disorders | Human | — | Not specified | Ketogenic Diet and Inflammation: Implications for Mood and Anxiety Disorders.cited 5× |
| Modified Atkins Diet (MAD) | Decreases - significant improvement | anxiety | Human | MAD group | Not specified (Modified Atkins Diet protocol used). | The impact of ketogenic diet on the frequency of psychogenic non-epileptic seizures (PNES): A feasibility randomized pilot study.cited 1× |
| Modified Atkins Diet (MAD) | Decreases - may reduce | symptoms of anxiety | Human | patients with PNES | Not specified (Modified Atkins Diet protocol used). | The impact of ketogenic diet on the frequency of psychogenic non-epileptic seizures (PNES): A feasibility randomized pilot study.cited 1× |
| a gluten-free diet (GFD) | Decreases - had marked mean improvements | hospital anxiety and depression scores | Human | both groups | Not specified (dietitian-led GFD). | Efficacy of a Gluten-Free Diet in Subjects With Irritable Bowel Syndrome-Diarrhea Unaware of Their HLA-DQ2/8 Genotype.cited 83× |
| genotype, diet, and genotype x diet | No effect - effects in | anxiety-related tasks | Animal | humanized mouse model (expressing E3 or E4) | Not specified | Effects of a high-fat diet on cognition and brain distribution of intranasal insulin in E3 and E4 male and female mice.cited 1× |
| conventional nutritional therapy according to the recommendations of the German Nutrition Society including the low-FODMAP diet | No effect - no significant group differences | anxiety and depression (HADS) | Human | patients with irritable bowel syndrome (IBS) | Not specified (conventional nutritional therapy followed German Nutrition Society recommendations, including low-FODMAP diet). | Ayurvedic vs. Conventional Nutritional Therapy Including Low-FODMAP Diet for Patients With Irritable Bowel Syndrome-A Randomized Controlled Trial.cited 5× |
| a strict gluten-free diet (GFD) | Decreases - a significant improvement was observed | anxiety symptoms and paranoid delusion | Human | a 15-year-old girl with no past psychiatric history | Not specified | Effects of a Gluten-Free Diet in a Teenager Presenting With Psychosis. |
| Tinospora cordifolia stem powder (TCP) supplemented diet | Decreases - showed improvement | anxiety-like behavior | Animal | acyclic female rats | Not specified | Dietary Supplementation With Tinospora cordifolia Improves Anxiety-Type Behavior and Cognitive Impairments in Middle-Aged Acyclic Female Rats.cited 2× |
| high polyphenol diet (HPD) | No effect - No differences | anxiety | Human | mildly hypertensive participants aged 40-65 years | Not specified | A High Polyphenol Diet Improves Psychological Well-Being: The Polyphenol Intervention Trial (PPhIT).cited 26× |
| MIND low-calorie diet | Increases - significant improvement | anxiety | Human | type 2 diabetic women with insomnia | Not specified (low-calorie MIND diet vs. low-calorie diet as control). | The effect of MIND diet on sleep status, mental health, and serum level of BDNF in overweight/obese diabetic women with insomnia: a randomized controlled trial. |
| low-FODMAP combined gluten-free diet (LF-GFD) | Decreases - reduces | anxiety and depression | Human | individuals diagnosed with irritable bowel syndrome | Not specified | Efficacy and Safety of a Low-FODMAP Diet in Combination with a Gluten-Free Diet for Adult Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.cited 1× |
| DASH diet | No effect - anxiety outcomes remained comparable | anxiety | Human | women with migraine | The DASH diet provided 15-20% of total daily energy from proteins, 25-30% from fats, and 55-60% from carbohydrates. | Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on clinical, quality of life and mental health outcomes in women with migraine: a randomised controlled trial.cited 15× |
| Tinospora cordifolia stem powder (TCP) supplementation in high fat diet | Decreases - showed reduced | anxiety-like behavior | Animal | high fat diet-induced obesity rat model system (HFDE rats) | Not specified (stem powder of T. cordifolia supplemented in high-fat diet). | Tinospora cordifolia ameliorates brain functions impairments associated with high fat diet induced obesity.cited 13× |
| highest quartile of MIND diet | Decreases - exhibited significantly lower risks | anxiety | Human | participants from the PERSIAN Organizational Cohort Study in Mashhad (POCM) | Not specified | Nourishing the mind: how the EAT-Lancet reference diet (ELD) and MIND diet impact stress, anxiety, and depression.cited 2× |
| MIND diet | Decreases - was associated with decreased likelihood | anxiety | Human | — | Not specified | Nourishing the mind: how the EAT-Lancet reference diet (ELD) and MIND diet impact stress, anxiety, and depression.cited 2× |
| A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD) | Decreases - improving | anxiety | Human | IBS patients | Not specified | A Low-FODMAP Diet for Irritable Bowel Syndrome: Some Answers to the Doubts from a Long-Term Follow-Up.cited 40× |
| A low FODMAP diet (LFD) | No effect - not in the anxiety and depression state | anxiety and depression state | Human | IBS patients | Not specified | Effects of a low FODMAP diet on the symptom management of patients with irritable bowel syndrome: a systematic umbrella review with the meta-analysis of clinical trials.cited 6× |
| MIND diet | Decreases - had significantly lower odds of | anxiety | Human | a large sample of the Iranian adult population | Not specified (dietary intake assessed via FFQ). | The relation between MIND diet with psychological disorders and psychological stress among Iranian adults.cited 14× |
| diet only (low-carbohydrate and reduced energy diet) | Decreases - significant decrease | anxiety | Human | 45 obese patients | 30 g of carob/day (prebiotics), one tablet/day (probiotics). | A clinical trial about effects of prebiotic and probiotic supplementation on weight loss, psychological profile and metabolic parameters in obese subjects.cited 20× |
| low carbohydrate diet | Increases - increases | anxiety | Human | — | Not specified (carbohydrate intake varied, with one subgroup at <26%). | Effect of low-carbohydrate diet on depression and anxiety: A systematic review and meta-analysis of controlled trials.cited 13× |
| low carbohydrate diet | Increases - increases | anxiety | Human | — | Not specified (carbohydrate intake varied, with one subgroup at <26%). | Effect of low-carbohydrate diet on depression and anxiety: A systematic review and meta-analysis of controlled trials.cited 13× |
| low carbohydrate diet | Increases - increases | anxiety | Human | — | Not specified (carbohydrate intake varied, with one subgroup at <26%). | Effect of low-carbohydrate diet on depression and anxiety: A systematic review and meta-analysis of controlled trials.cited 13× |
| low carbohydrate diet | No effect - did not show any significant association | anxiety | Human | patients without a mood disorder | Not specified (carbohydrate intake varied, with one subgroup at <26%). | Effect of low-carbohydrate diet on depression and anxiety: A systematic review and meta-analysis of controlled trials.cited 13× |
| low carbohydrate diet | Increases - significantly increases | anxiety | Human | — | Not specified (carbohydrate intake varied, with one subgroup at <26%). | Effect of low-carbohydrate diet on depression and anxiety: A systematic review and meta-analysis of controlled trials.cited 13× |
| low carbohydrate diet | No effect - did not demonstrate significant association | depression and anxiety | Human | — | Not specified (carbohydrate intake varied, with one subgroup at <26%). | Effect of low-carbohydrate diet on depression and anxiety: A systematic review and meta-analysis of controlled trials.cited 13× |
| low-carbohydrate diet (LCD) | Decreases - showed improvements in | anxiety | Human | adults with acquired limb loss | Not specified (only described as a "low-carbohydrate diet"). | Investigation of the Impact of a Low-Carbohydrate Diet on The Chronic Pain Experience Among Adults with an Acquired Limb Loss: A Pilot Study. |
| diet supplemented with the plant-derived n-3 PUFA α-linolenic acid (ALA) and antioxidants (provided by n-3 PUFAs-rich rapeseed oil fortified with a mix of naturally constituting antioxidant micronutrients, including coenzyme Q10, tocopherol, and the phenolic compound canolol) | No effect - did not improve | anxiety-like behavior | Animal | db/db mice | Not specified | Rapeseed oil fortified with micronutrients improves cognitive alterations associated with metabolic syndrome.cited 5× |
| cafeteria-style Western diet (CAF) | No effect - was not associated with long-term changes in | anxiety-like behavior | Animal | rats | Cafeteria-style Western Diet (various high-fat/high-sugar foods) ad libitum. | Western diet consumption impairs memory function via dysregulated hippocampus acetylcholine signaling.cited 2× |
| low-FODMAP diet | Decreases - significant reductions | anxiety | Human | IBS patients | Not specified | Low-FODMAP Diet Is Associated With Improved Quality of Life in IBS Patients-A Prospective Observational Study.cited 21× |
| low FODMAP diet | Decreases - significant reductions | anxiety | Human | adults over 65 years with chronic diarrhea | Not specified (dietitian-led dietary intervention) | A Low FODMAP Diet Is Nutritionally Adequate and Therapeutically Efficacious in Community Dwelling Older Adults with Chronic Diarrhoea.cited 13× |