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A Low-FODMAP Diet for Irritable Bowel Syndrome: Some Answers to the Doubts from a Long-Term Follow-Up.

Nutrients
August 7, 2020
Massimo Bellini et al. (11 authors)
Evaluation StudyJournal ArticleHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the short- and long-term efficacy, nutritional adequacy, and patient acceptability of a Low-FODMAP Diet (LFD) for managing irritable bowel syndrome (IBS).

Results Summary

The LFD effectively controlled digestive symptoms and improved quality of life, anxiety, and depression in both short- and long-term use, though adherence decreased over time. Nutritional adequacy was maintained, but trigger food perception changed after reintroduction.

Population

73 IBS patients, with 41 evaluated in long-term follow-up (6-24 months).

Effective Dosage

Not specified

Duration

Initial LFD for 2 months, followed by reintroduction phase, with long-term follow-up at 6-24 months.

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD)
decrease
digestive symptoms
IBS patients
-
was effective in controlling
#1
A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD)
increase
quality of life
IBS patients
-
improving
#2
A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD)
decrease
anxiety
IBS patients
-
improving
#3
A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD)
decrease
depression
IBS patients
-
improving
#4
A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD)
increase
food-related quality of life
IBS patients
-
improved
#5
A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD)
no change
nutritional adequacy
IBS patients
-
without affecting
#6
A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD)
decrease
adherence
IBS patients
-
decreased
#7
Abstract

A low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet (LFD) is a possible therapy for irritable bowel syndrome (IBS). This study investigates the short- and long-term efficacy and nutritional adequacy of an LFD and the patients' long-term acceptability. Patients' adherence and ability to perceive the "trigger" foods were also evaluated. Seventy-three IBS patients were given an LFD (T0) and after 2 months (T1), 68 started the reintroduction phase. At the end of this period (T2), 59 were advised to go on an Adapted Low-FODMAP Diet (AdLFD) and 41 were evaluated again after a 6-24 month follow-up (T3). At each time, questionnaires and Biolectrical Impedance Vector Analysis (BIVA) were performed. The LFD was effective in controlling digestive symptoms both in the short- and long-term, and in improving quality of life, anxiety and depression, even if some problems regarding acceptability were reported and adherence decreased in the long term. The LFD improved the food-related quality of life without affecting nutritional adequacy. When data collected at T0 were compared with those collected at T2, the perception of trigger foods was quite different. Even if some problems of acceptability and adherence are reported, an LFD is nutritionally adequate and effective in improving IBS symptoms also in the long term.

Medical Subject Headings (MeSH)
AdultAnthropometryDiet, Carbohydrate-RestrictedDisaccharidesElectric ImpedanceFemaleFermentationFollow-Up StudiesHumansIrritable Bowel SyndromeMaleMiddle AgedMonosaccharidesNutrition AssessmentNutritional StatusOligosaccharidesPatient CompliancePolymersQuality of LifeTime FactorsTreatment Outcome
Study Links
Quality Scores
Safety85
Efficacy80/10
Quality75/10
Citation Metrics
Total Citations40
Citations/Year8.0
Relative Citation Ratio2.78
NIH Percentile83.3%
Research Impact Scores
APT Score0.95
Weight Score1.23
Normalized Score0.81
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A Low-FODMAP Diet for Irritable Bowel Syndrome: Some Answers... | Panacea Index