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Evidence suggests Ketogenic Diet maydecreaseCognitive decline.
33 studies (45 claims)
Moderate consensus
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| healthy diet with fish and polyunsaturated fatty acids (PUFAs) | Decreases - highlighting the benefits | cognitive decline | Human | — | Not specified | An analysis of omega-3 clinical trials and a call for personalized supplementation for dementia prevention.cited 7× |
| higher adherence to the MIND diet | Decreases - was associated with potentially slower | cognitive decline | Human | middle-aged and older adults | Not specified (MIND diet score range: 0-12). | Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet and Cognitive Function and its Decline: A Prospective Study and Meta-analysis of Cohort Studies.cited 25× |
| Mediterranean diet and its peculiar foods and nutrients | Decreases - exert beneficial effects against | cognitive decline | Human | — | — | Mediterranean Diet on Sleep: A Health Alliance.cited 51× |
| Participants in the lowest tertile of the DASH diet who reported hearing loss | Increases - exhibited a faster cognitive decline | cognitive decline | Human | participants who reported hearing loss | Not specified | Hearing loss, diet, and cognitive decline: interconnections for dementia prevention. |
| Participants in the highest tertile of the DASH diet score who reported hearing loss | Increases - experienced a faster cognitive decline | cognitive decline | Human | participants who reported hearing loss | Not specified | Hearing loss, diet, and cognitive decline: interconnections for dementia prevention. |
| Healthy dietary patterns, particularly the DASH diet | Decreases - was associated with slower cognitive decline following hearing loss | cognitive decline following hearing loss | Human | older adults | Not specified | Hearing loss, diet, and cognitive decline: interconnections for dementia prevention. |
| nutraceuticals present in a wide variety of plants, fruits and seeds, natural vitamins or their analogues, synthetic antioxidants and other compounds taken with the diet | Decreases - can ameliorate | cognitive decline of brain aging | Human | — | Not specified | Biochemical deficits and cognitive decline in brain aging: Intervention by dietary supplements.cited 35× |
| adherence to Mediterranean diet | Decreases - seem to be very promising | delay of cognitive decline | Human | normal aging | Not specified | Cognitive decline in normal aging and its prevention: a review on non-pharmacological lifestyle strategies.cited 70× |
| a diet simultaneously high in SFA and Cu | Increases - revealed an association | cognitive decline | Human | — | Not specified | Copper and iron in Alzheimer's disease: a systematic review and its dietary implications.cited 61× |
| the MIND diet | Decreases - can slow | cognitive decline | Human | — | Not specified | The Mediterranean-dietary approaches to stop hypertension diet intervention for neurodegenerative delay (MIND) diet: a bibliometric analysis.cited 4× |
| high-carbohydrate diet (HCD) | Increases - exacerbated | cognitive decline | Animal | db/db mice | Not specified | A High-Carbohydrate Diet Induces Cognitive Impairment and Promotes Amyloid Burden and Tau Phosphorylation via PI3K/Akt/GSK-3β Pathway in db/db Mice. |
| Western diet (WD) | Increases - induces | cognitive decline | Animal | — | Not specified | Intestinal Microbiota Remodeling Protects Mice from Western Diet-Induced Brain Inflammation and Cognitive Decline.cited 18× |
| MIND diet adherence | Decreases - may reduce | cognitive decline | Human | — | Not specified | Adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and exposure to selenium species: A cross-sectional study.cited 6× |
| Mediterranean-style diet and regular walking, delivered through motivational interviewing and cognitive-behavioral therapy (MI-CBT) | Decreases - reduce | age-associated cognitive decline | Human | older, independently living individuals without cognitive impairment | Not specified | A Mediterranean Diet and Walking Intervention to Reduce Cognitive Decline and Dementia Risk in Independently Living Older Australians: The MedWalk Randomized Controlled Trial Experimental Protocol, Including COVID-19 Related Modifications and Baseline Characteristics.cited 2× |
| greater long-term adherence to the MIND diet | No effect - was not associated with | cognitive decline over 6 years in global cognition | Human | 16,058 older women aged 70 and over from the Nurses' Health Study | Not specified (dietary intake assessed via Food Frequency Questionnaire). | Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women.cited 109× |
| greater long-term adherence to the MIND diet | No effect - was not associated with | cognitive decline over 6 years in TICS | Human | 16,058 older women aged 70 and over from the Nurses' Health Study | Not specified (dietary intake assessed via Food Frequency Questionnaire). | Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women.cited 109× |
| greater long-term adherence to the MIND diet | No effect - was not associated with | cognitive decline over 6 years in verbal memory | Human | 16,058 older women aged 70 and over from the Nurses' Health Study | Not specified (dietary intake assessed via Food Frequency Questionnaire). | Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women.cited 109× |
| adherence to the MIND diet at baseline | No effect - was not associated with | cognitive decline | Human | adults ≥70 years | Not specified | Adherence to the MIND diet and the odds of mild cognitive impairment in generally healthy older adults: The 3-year DO-HEALTH study. |
| Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet | Increases - is associated with both higher cognition and slower rates of cognitive decline | cognition and cognitive decline | Human | deceased older adults | Not specified | The association of MIND diet with cognitive resilience to neuropathologies.cited 16× |
| Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet | Decreases - associated with a slower decline | cognitive decline | Human | older adults with type 2 diabetes mellitus (T2D) | Not specified | Greater intake of the MEDI diet is associated with better cognitive trajectory in older adults with type 2 diabetes.cited 10× |
| Mediterranean (MEDI) diet | Decreases - associated with a slower decline | cognitive decline | Human | older adults with type 2 diabetes mellitus (T2D) | Not specified | Greater intake of the MEDI diet is associated with better cognitive trajectory in older adults with type 2 diabetes.cited 10× |
| Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet | No effect - examines the effects | cognitive decline | Human | a population at risk for cognitive decline with a suboptimal diet | Not specified | Higher circulating α-carotene was associated with better cognitive function: an evaluation among the MIND trial participants.cited 20× |
| Mediterranean-DASH (Dietary Approaches to Stop Hypertension) Intervention for Neurodegenerative Delay (MIND) diet | Decreases - reduced | risk of cognitive decline | Human | 40-55-year olds living in Northern Ireland (NI) and Italy | Not mentioned | Comparison of barriers and facilitators of MIND diet uptake among adults from Northern Ireland and Italy.cited 13× |
| dash diet | Decreases - have been shown to slow | cognitive decline | Human | — | Not specified | MIND diet slows cognitive decline with aging.cited 559× |
| Mediterranean diet | Decreases - have been shown to slow | cognitive decline | Human | — | Not specified | MIND diet slows cognitive decline with aging.cited 559× |
| MIND diet | Decreases - substantially slows | cognitive decline with age | Human | — | Not specified | MIND diet slows cognitive decline with aging.cited 559× |
| higher MIND diet | Decreases - was associated with slower | cognitive decline | Human | older adults | Not specified (MIND diet score range: 0-15, with tertiles analyzed). | Association of MIND diet with cognitive decline among Black and White older adults.cited 2× |
| MIND diet | Decreases - was associated with slower | cognitive decline | Human | Black and White older adults | Not specified (MIND diet score range: 0-15, with tertiles analyzed). | Association of MIND diet with cognitive decline among Black and White older adults.cited 2× |
| MIND diet | Decreases - was associated with slower | cognitive decline | Human | White participants | Not specified (MIND diet score range: 0-15, with tertiles analyzed). | Association of MIND diet with cognitive decline among Black and White older adults.cited 2× |
| MIND diet | Decreases - was associated with slower | cognitive decline | Human | White participants | Not specified (MIND diet score range: 0-15, with tertiles analyzed). | Association of MIND diet with cognitive decline among Black and White older adults.cited 2× |
| MIND diet | Decreases - was associated with slower | cognitive decline | Human | Black participants | Not specified (MIND diet score range: 0-15, with tertiles analyzed). | Association of MIND diet with cognitive decline among Black and White older adults.cited 2× |
| Adherence to Mediterranean-DASH Diet Intervention for Neurodegenerative Delay (MIND) | Decreases - associated with a slower rate | cognitive decline | Human | older US men and women in MAP | Not specified | Adherence to MIND Diet, Genetic Susceptibility, and Incident Dementia in Three US Cohorts.cited 19× |
| Adherence to Mediterranean-DASH Diet Intervention for Neurodegenerative Delay (MIND) | No effect - not associated with | cognitive decline | Human | older US men and women in CHAP | Not specified | Adherence to MIND Diet, Genetic Susceptibility, and Incident Dementia in Three US Cohorts.cited 19× |
| Adherence to Mediterranean-DASH Diet Intervention for Neurodegenerative Delay (MIND) | No effect - no gene−diet interaction | cognitive decline | Human | older US men and women across cohorts | Not specified | Adherence to MIND Diet, Genetic Susceptibility, and Incident Dementia in Three US Cohorts.cited 19× |
| Mediterranean diet | Decreases - is associated with lower prevalence | age-associated cognitive decline | Human | — | Not specified | Extra-virgin olive oil for potential prevention of Alzheimer disease.cited 42× |
| Mediterranean diet (MeDiet) | Decreases - play a protective effect against | cognitive decline | Human | — | Not specified | Effect of nutrition on neurodegenerative diseases. A systematic review.cited 138× |
| diet and nutrition | No effect - impact | age-associated cognitive decline | Human | — | Not specified | Unusual Bioactive Compounds with Antioxidant Properties in Adjuvant Therapy Supporting Cognition Impairment in Age-Related Neurodegenerative Disorders.cited 13× |
| MIND diet | Decreases - was associated with a slower rate of | cognitive decline | Human | participants after stroke | Not specified (dietary components included whole grains, leafy greens, berries, beans, nuts, lean meats, fish, poultry, olive oil, and reduced intake of cheese, butter, fried foods, and sweets). | Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke.cited 63× |
| MIND diet | Decreases - had a slower rate of | global cognitive decline | Human | participants with a clinical history of stroke | Not specified (dietary components included whole grains, leafy greens, berries, beans, nuts, lean meats, fish, poultry, olive oil, and reduced intake of cheese, butter, fried foods, and sweets). | Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke.cited 63× |
| MIND diet | Decreases - slowing | cognitive decline | Human | older adults at risk for Alzheimer's dementia | Not specified | Properties of the Cognitive Function Battery for the MIND Diet Intervention to Prevent Alzheimer's Disease.cited 6× |
| MIND diet | Decreases - protective effects on | cognitive decline | Human | adults aged ≥40 y | Not specified | The Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet for the Aging Brain: A Systematic Review.cited 18× |
| MIND diet | Decreases - slows | cognitive decline | Human | — | Not specified | Plasma Proteins Associated with the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet and Incident Dementia.cited 1× |
| an antioxidant-rich diet | Decreases - may represent a viable intervention to mitigate | age-related cognitive decline | Human | the elderly | Not specified | The role of composite dietary antioxidants in elderly cognitive function: insights from NHANES.cited 3× |