Greater intake of the MEDI diet is associated with better cognitive trajectory in older adults with type 2 diabetes.
Study Goal
To determine the association of the DASH diet with cognitive decline in older adults with type 2 diabetes mellitus (T2D).
Results Summary
The study found that while high adherence to the MIND and MEDI diets was associated with slower cognitive decline, the DASH diet did not show significant independent associations with cognitive outcomes in the multivariable model.
Population
Older adults with type 2 diabetes mellitus (N = 960).
Effective Dosage
Not specified
Duration
Mean follow-up of 4.1 ± 2.1 years
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Mediterranean (MEDI) diet | decrease | cognitive decline | older adults with type 2 diabetes mellitus (T2D) | - | associated with a slower decline | #1 |
Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet | decrease | cognitive decline | older adults with type 2 diabetes mellitus (T2D) | - | associated with a slower decline | #2 |
higher MEDI diet intake | decrease | decline in global cognition | older adults with type 2 diabetes mellitus (T2D) | β = 0.013, SE = 0.006; P = 0.042 | remained significant | #3 |
higher MEDI diet intake | decrease | decline in executive functions | older adults with type 2 diabetes mellitus (T2D) | β = 0.001, SE = 0.008, Pv = 0.023 | remained significant | #4 |
adherence to the MEDI | increase | cognitive trajectory | older adults with T2D | - | is related to better cognitive trajectory | #5 |
AIMS: To determine associations of three dietary patterns (Mediterranean (MEDI) diet, the Dietary Approaches to Stop Hypertension (DASH) diet and the Mediterranean- DASH Intervention for Neurodegenerative Delay (MIND) diet) with cognitive decline in older adults with type 2 diabetes mellitus (T2D). METHODS: This is a longitudinal observational study. Participants (N = 960) from the Israel Diabetes and Cognitive Decline (IDCD) study were included in this study. A multivariable-adjusted model including all three dietary patterns concurrently was developed to investigate their independent effect on cognitive decline. RESULTS: The mean follow up was 4.1 ± 2.1 years. While high adherence to both the MIND and the MEDI diet was associated with a slower decline, in the multivariable model only the associations of higher MEDI diet intake with greater decline in global cognition and in executive functions remained significant (β = 0.013, SE = 0.006; P = 0.042; β = 0.001, SE = 0.008, Pv = 0.023 respectively). CONCLUSIONS: In older adults with T2D, adherence to the MEDI is related to better cognitive trajectory. Diet is a meaningful factor in the path linking T2D and cognition.