Properties of the Cognitive Function Battery for the MIND Diet Intervention to Prevent Alzheimer's Disease.
Study Goal
The researchers aimed to evaluate the validity of the cognitive battery used in the MIND Diet Intervention to measure cognitive decline and brain atrophy in older adults at risk for Alzheimer's dementia.
Results Summary
The study found that the MIND cognitive battery effectively measured four distinct cognitive domains (executive function, perceptual speed, episodic memory, and semantic memory) and showed expected associations with age, education, and cognitive activity. The results support the battery's validity for use in diet intervention trials.
Population
Older adults (average age 70 years) at risk for Alzheimer's dementia.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
MIND diet | decrease | cognitive decline | older adults at risk for Alzheimer's dementia | - | slowing | #1 |
MIND diet | decrease | brain atrophy | older adults at risk for Alzheimer's dementia | - | reducing | #2 |
OBJECTIVE: To evaluate the properties of the cognitive battery used in the MIND Diet Intervention to Prevent Alzheimer's Disease. The MIND Diet Intervention is a randomized control trial to determine the relative effectiveness of the MIND diet in slowing cognitive decline and reducing brain atrophy in older adults at risk for Alzheimer's dementia. METHODS: The MIND cognitive function battery was administered at baseline to 604 participants of an average age of 70 years, who agreed to participate in the diet intervention study, and was designed to measure change over time. The battery included 12 cognitive tests, measuring the 4 cognitive domains of executive function, perceptual speed, episodic memory, and semantic memory. We conducted a principal component analysis to examine the consistency between our theoretical domains and the statistical performance of participants in each domain. To further establish the validity of each domain, we regressed the domain scores against a late-life cognitive activity score, controlling for age, race, sex, and years of education. RESULTS: Four factors emerged in the principal component analyses that were similar to the theoretical domains. In regression equations, we found the expected associations with age, education, and late-life cognitive activity with each of the four cognitive domains. CONCLUSIONS: These results indicate that the MIND cognitive battery is a comprehensive and valid battery of four separate domains of cognitive function that can be used in diet intervention trials for older adults.