Association of MIND diet with cognitive decline among Black and White older adults.
Study Goal
The researchers aimed to examine the association between the MIND diet and cognitive decline in older adults, specifically comparing outcomes between Black and White participants.
Results Summary
Higher adherence to the MIND diet was associated with slower cognitive decline in both Black and White older adults, though the association was stronger and more consistent among White participants. The effect was attenuated for Black participants when accounting for vascular and lifestyle factors.
Population
5,259 older adults (73.5 ± 6.0 years, 62% Black, 62% female) from the Chicago Health and Aging Project.
Effective Dosage
Not specified (MIND diet score range: 0-15, with tertiles analyzed).
Duration
7.8 ± 4.6 years (follow-up period).
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
higher MIND diet | decrease | cognitive decline | older adults | - | was associated with slower | #1 |
MIND diet | decrease | cognitive decline | Black and White older adults | - | was associated with slower | #2 |
MIND diet | decrease | cognitive decline | White participants | β = 0.0121 [95% confidence interval [CI]: 0.0006, 0.0237] | was associated with slower | #3 |
MIND diet | decrease | cognitive decline | White participants | β = 0.0146 [95% CI: 0.0003, 0.0260] | was associated with slower | #4 |
MIND diet | decrease | cognitive decline | Black participants | β = 0.0088 [95% CI: 0.0003, 0.0172] | was associated with slower | #5 |
INTRODUCTION: We examined the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet's association with cognitive decline by race among older adults in the Chicago Health and Aging Project. METHODS: Five thousand two hundred fifty-nine participants (73.5 [± 6.0] years, 62% Black participants, 62% female) completed a food frequency questionnaire, and two or more cognitive assessments over 7.8 ± 4.6 years. RESULTS: Overall, higher MIND diet was associated with slower cognitive decline (p for trend = 0.0025). The MIND score (range:0-15) was different between Black and White older adults(6.97 vs. 7.12, p = 0.010). Compared to the lowest tertile, among White participants, the two highest tertiles (MIND score -7: β = 0.0121 [95% confidence interval [CI]: 0.0006, 0.0237]; MIND score -8.5: β = 0.0146 [95% CI: 0.0003, 0.0260]) and among Black participants, only the highest tertile (MIND score -8.5: β = 0.0088 [95% CI: 0.0003, 0.0172]) had association with cognitive decline. Vascular and lifestyle factors attenuated the association only for Black older adults. DISCUSSION: The MIND diet was associated with slower cognitive decline in Black and White older adults, but this may vary with other lifestyle and vascular factors. Further research is warranted on race-specific cultural diets considering other risk factors for cognitive decline. HIGHLIGHTS: The intake of Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet components varies by race. The MIND diet may slow cognitive decline in both Black and White older adults. This association may vary with other lifestyle and vascular risk factors.