41
120
35
↑41
↓120
—35
Evidence suggests Ketogenic Diet maydecreaseTriglycerides.
155 studies (196 claims)
Moderate consensus
Typical effective dose 140000 (140000–140000) mgacross 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| diet regimen | Decreases - highly statistically significant decrease | triglycerides (TG) | Human | postmenopausal obese women | LA treatment for 30 minutes, three times a week. | The effects of laser acupuncture on metabolic syndrome in obese postmenopausal women: a randomized controlled study. |
| combined laser acupuncture and diet regimen | Decreases - significantly lower | triglycerides (TG) | Human | postmenopausal obese women | LA treatment for 30 minutes, three times a week. | The effects of laser acupuncture on metabolic syndrome in obese postmenopausal women: a randomized controlled study. |
| high fructose diet (HFD) | Increases - increased significantly | plasma triglycerides | HumanAnimalMolecular | male Sprague-Dawley rats | 200, 400, and 800 mg/kg/day of RGC. | Red grape berry-cultured cells reduce blood pressure in rats with metabolic-like syndrome.cited 13× |
| high-fructose diet | Increases - increased | triglycerides | Animal | Wistar albino rats | Not specified (high-fructose diet for 15 weeks; metformin administered once daily for the last 6 weeks) | Impact of high-fructose diet and metformin on histomorphological and molecular parameters of reproductive organs and vaginal microbiota of female rat.cited 1× |
| high fructose (HF) diet | Increases - significantly elevated | triglycerides | Animal | obese Wister male rats | RSV at 30 mg/kg/day | Role of trans-resveratrol in ameliorating biochemical and molecular alterations in obese rats induced by a high fructose/fat diet. |
| high-fructose high-fat (HF/HFAT) diet | Increases - significantly elevated | triglycerides | Animal | obese Wister male rats | RSV at 30 mg/kg/day | Role of trans-resveratrol in ameliorating biochemical and molecular alterations in obese rats induced by a high fructose/fat diet. |
| 5-day, high-fat diet rich in cottonseed oil (CSO) | Decreases - were lower following | fasting triglycerides (TG) | Human | fifteen normal-weight men | 50% fat diet rich in either CSO or OO. | A 5-day high-fat diet rich in cottonseed oil improves cholesterol profiles and triglycerides compared to olive oil in healthy men.cited 12× |
| phytosterol capsule supplementation associated with the National Cholesterol Education Program (NCEP) Step 2 diet | No effect - No significant reduction was observed | triglycerides | Human | children and adolescents with dyslipidemia | Not specified | Effect of phytosterol capsule supplementation associated with the National Cholesterol Education Program Step 2 diet on low-density lipoprotein in children and adolescents with dyslipidemia: A double-blind crossover trial.cited 4× |
| egg-enriched diet | Decreases - had lower | plasma triglycerides | Animal | Sprague-Dawley rats | — | An egg-enriched diet attenuates plasma lipids and mediates cholesterol metabolism of high-cholesterol fed rats. |
| high-fat/high-fructose diet plus O. viverrini infection | Increases - had the highest concentrations | triglycerides | Animal | male golden hamsters | Not specified (described as "high-fat/high-fructose diet"). | High-fat/high-fructose diet and Opisthorchis viverrini infection promote metabolic dysfunction-associated steatotic liver disease via inflammation, fibrogenesis, and metabolic dysfunction. |
| diet supplemented with a predominantly saturated vegetable oil | Increases - significant effect | cholesterol and triglycerides | Animal | exercising Thoroughbred horses | Approximately 12% of digestible energy (DE) from the oil source for 10 months, then increased to 20% DE for an additional 6 months. | Effect of feeding thoroughbred horses a high unsaturated or saturated vegetable oil supplemented diet for 6 months following a 10 month fat acclimation.cited 7× |
| diet supplemented with a predominantly unsaturated vegetable oil | Increases - significant effect | cholesterol and triglycerides | Animal | exercising Thoroughbred horses | Approximately 12% of digestible energy (DE) from the oil source for 10 months, then increased to 20% DE for an additional 6 months. | Effect of feeding thoroughbred horses a high unsaturated or saturated vegetable oil supplemented diet for 6 months following a 10 month fat acclimation.cited 7× |
| fat-restricted low-glycemic index diet | Decreases - significantly reduced | triglycerides | Human | overweight/obese Southwest Chinese individuals | Daily energy intake reduced by 300-500 kcal, with low-glycemic index carbohydrate-energy ratio <45% and fat-energy ratio 25-30%. | Fat-restricted low-glycemic index diet controls weight and improves blood lipid profile: A pilot study among overweight and obese adults in Southwest China.cited 1× |
| fat-restricted low-glycemic index diet | Decreases - might be helpful for lowering | triglycerides | Human | overweight/obese individuals in Southwest China | Daily energy intake reduced by 300-500 kcal, with low-glycemic index carbohydrate-energy ratio <45% and fat-energy ratio 25-30%. | Fat-restricted low-glycemic index diet controls weight and improves blood lipid profile: A pilot study among overweight and obese adults in Southwest China.cited 1× |
| very low carbohydrate diet (VLCD) | Decreases - decreases in | triglycerides | Human | older adults with obesity | VLCD (<10% energy from carbohydrates, 25% from protein, >65% from fat); LFD (55% carbohydrates, 25% protein, 20% fat). | Effects of weight loss during a very low carbohydrate diet on specific adipose tissue depots and insulin sensitivity in older adults with obesity: a randomized clinical trial.cited 37× |
| hypercaloric diet rich in lipids and simple carbohydrates | Increases - had a higher | liver triglycerides | Animal | Male Wistar rats | 250 mg/kg administered intraperitoneally. | Effects of carnosine supplementation on markers for the pathophysiological development of metabolic dysfunction-associated steatotic liver disease in a diet-induced model.cited 2× |
| hypercaloric diet rich in lipids and simple carbohydrates | Increases - had a higher | plasma triglycerides | Animal | Male Wistar rats | 250 mg/kg administered intraperitoneally. | Effects of carnosine supplementation on markers for the pathophysiological development of metabolic dysfunction-associated steatotic liver disease in a diet-induced model.cited 2× |
| modified diet group (MD) | Decreases - were within the reference range | triglycerides (TG) | Human | overweight and obese retired miners with lipid disorders | 1 hour of Nordic walking 3 times per week at 60-70% of maximal heart rate. | Effect of 12-Week Interventions Involving Nordic Walking Exercise and a Modified Diet on the Anthropometric Parameters and Blood Lipid Profiles in Overweight and Obese Ex-Coal Miners.cited 9× |
| 12-week hypocaloric ketogenic diet (KD) | Decreases - significant improvements were observed | triglycerides (TG) | Human | overweight, obese, and healthy-weight females | Less than 30 g of carbohydrates, approximately 60 g of protein, and 140 g of fat per day (80% unsaturated and 20% saturated fat). | Effects of a 12 Week Ketogenic Diet Intervention on Obese and Overweight Females with Glucose and Lipid Metabolism Disturbance.cited 2× |
| hypocaloric Mediterranean diet pattern for 9 months with a high amount of monounsaturated fatty acids | Decreases - significant improvement | triglycerides | Human | patients with the AA genotype | Not specified | Interaction of the variant in the adiponectin gene rs3774261 with serum lipid profile and adiponectin levels after 9 months with a high monounsaturated fat hypocaloric diet with Mediterranean pattern.cited 2× |
| hypocaloric fat monounsaturated diet | No effect - showed no improvement | triglycerides | Human | G allele carriers of ADIPOQ gene variant (rs3774261) | Not specified | Interaction of the variant in the adiponectin gene rs3774261 with serum lipid profile and adiponectin levels after 9 months with a high monounsaturated fat hypocaloric diet with Mediterranean pattern.cited 2× |
| low-carbohydrate/high-fat weight-loss diet | Decreases - lowering | triglycerides | Human | individuals with the CETP rs3764261 CC genotype | Not specified | CETP genotype and changes in lipid levels in response to weight-loss diet intervention in the POUNDS LOST and DIRECT randomized trials.cited 31× |
| high-fat diet | Decreases - decreases | triglycerides | Human | participants with the CETP rs3764261 CC genotype | Not specified | CETP genotype and changes in lipid levels in response to weight-loss diet intervention in the POUNDS LOST and DIRECT randomized trials.cited 31× |
| low-fat diet | No effect - no significant difference | triglycerides | Human | participants carrying other genotypes | Not specified | CETP genotype and changes in lipid levels in response to weight-loss diet intervention in the POUNDS LOST and DIRECT randomized trials.cited 31× |
| low-calorie DASH diet | Decreases - resulted in a significant decrease | serum triglycerides | Human | overweight or obese patients with PCOS | Not specified (diet included 52%-55% carbohydrates, 16%-18% proteins, and 30% total fats, with low-fat dairy as part of the DASH diet). | The effects of dietary approaches to stop hypertension diet on weight loss, anti-Müllerian hormone and metabolic profiles in women with polycystic ovary syndrome: A randomized clinical trial.cited 44× |
| representative typical American diet (TAD) | No effect - did not affect | fasting triglycerides | Human | overweight and obese women selected according to indexes of insulin resistance or dyslipidemia | Not specified (all foods and beverages were provided). | A randomized controlled-feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indexes.cited 25× |
| DGA-based diet | No effect - did not affect | fasting triglycerides | Human | overweight and obese women selected according to indexes of insulin resistance or dyslipidemia | Not specified (all foods and beverages were provided). | A randomized controlled-feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indexes.cited 25× |
| hypocaloric high-protein diet | Decreases - decreased | triglycerides | Human | NAFLD patients | Not specified | Hypocaloric high-protein diet improves clinical and biochemical markers in patients with nonalcoholic fatty liver disease (NAFLD).cited 29× |
| antiatherogenic vegetarian diet | Decreases - significantly decreased | triglycerides | Human | patients with CHD in VG | Not specified (dietary intervention only). | [Leveling the hyperlipidemic effect of beta-adrenoblockers by means of antiatherogenic vegetarian diet]. |
| routine mixed diet No. 10c | Increases - increased | triglycerides | Human | patients with CHD in CG | Not specified (dietary intervention only). | [Leveling the hyperlipidemic effect of beta-adrenoblockers by means of antiatherogenic vegetarian diet]. |
| low protein diet (LPD) | Decreases - significantly decreased | triglycerides | Human | advanced CKD adult patients | Not specified | Compliance, Adherence and Concordance Differently Predict the Improvement of Uremic and Microbial Toxins in Chronic Kidney Disease on Low Protein Diet.cited 9× |
| low protein diet (LPD) | Decreases - a reduction in | triglycerides | Human | sixty patients affected by advanced CKD | Not specified | Probiotics-Supplemented Low-Protein Diet for Microbiota Modulation in Patients with Advanced Chronic Kidney Disease (ProLowCKD): Results from a Placebo-Controlled Randomized Trial.cited 31× |
| weight loss diet rich in whole grains | Decreases - higher reductions in | triglycerides | Human | overweight and obese women | Not specified | Impact of Diets Rich in Whole Grains and Fruits and Vegetables on Cardiovascular Risk Factors in Overweight and Obese Women: A Randomized Clinical Feeding Trial.cited 26× |
| "prudent" diet | No effect - remained unchanged | average-values of triglycerides | Human | patients with hyperlipoproteinemia type IIa | "Prudent" diet (20% protein, 35% carbohydrates, 45% fats, PS-factor ~2.2) for 7-10 days; clofibrate (500 mg twice daily) for 14 days. | [Treatment of hyperlipoproteinemia type IIa with a "prudent" diet and clofibrate (author's transl)]. |
| low-carbohydrate diet pattern | Decreases - a decrease was greater for triglycerides | triglycerides | Human | Women who completed treatment for breast cancer | Not specified (menu and recipe-defined dietary patterns). | Effect of dietary patterns differing in carbohydrate and fat content on blood lipid and glucose profiles based on weight-loss success of breast-cancer survivors.cited 24× |
| n-3-rich diet | Decreases - decreased | triglycerides | Human | kidney transplant recipients in the DIET group | Not specified (diet-based intervention) | Effects of a diet rich in N-3 polyunsaturated fatty acids on systemic inflammation in renal transplant recipients.cited 12× |
| new omega-3 fatty acid and medium-chain triglyceride-rich formula diet | Decreases - decreased | plasma triglycerides | Human | patients with severe hypertriglyceridemia | Not specified (formula diet composition details not provided). | Successful treatment of severe hypertriglyceridemia with a formula diet rich in omega-3 fatty acids and medium-chain triglycerides.cited 19× |
| carbohydrate-restricted diet (<20 g/d) | Decreases - decreased | liver triglycerides | Human | NAFLD subjects | Not specified for alanine (study focused on dietary carbohydrate restriction <20 g/d or calorie restriction 1200-1500 kcal/d). | Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction.cited 230× |
| calorie-restricted diet (1200-1500 kcal/d) | Decreases - decreased | liver triglycerides | Human | NAFLD subjects | Not specified for alanine (study focused on dietary carbohydrate restriction <20 g/d or calorie restriction 1200-1500 kcal/d). | Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction.cited 230× |
| diet enriched by green leafy vegetables and with a moderate restriction of carbohydrate intake | Decreases - decreased | triglycerides | Human | patients with NAFLD | One portion of green leafy vegetables daily, replacing one portion of carbohydrate-rich food. | The Replacement of Only One Portion of Starchy Carbohydrates with Green Leafy Vegetables Regresses Mid and Advanced Stages of NAFLD: Results from a Prospective Pilot Study.cited 3× |
| methyl donor deficient diet | Increases - increased | triglycerides | Animal | deprived rats | — | Methyl donor deficiency impairs fatty acid oxidation through PGC-1α hypomethylation and decreased ER-α, ERR-α, and HNF-4α in the rat liver. |
| energy-restricted diet | Decreases - improved | triglycerides | Human | overweight and obese women with PCOS | 12 × 10^9 CFU/day of Lactobacillus rhamnosus. | A low glycemic index, energy-restricted diet but not Lactobacillus rhamnosus supplementation changes fecal short-chain fatty acid and serum lipid concentrations in women with overweight or obesity and polycystic ovary syndrome.cited 20× |
| maternal Western-style diet induced obesity | Increases - had higher | circulating triglycerides | HumanAnimal | fetuses from OB-WSD mothers | Not specified | Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates.cited 40× |
| VLCHF diet | Decreases - decreased | triglycerides | Human | individuals with overweight and obesity | Not specified | A lipidomic and metabolomic signature of a very low-carbohydrate high-fat diet and high-intensity interval training: an additional analysis of a randomized controlled clinical trial.cited 6× |
| high-fat diet (HFD) | Increases - increased | circulating levels of triglycerides | Animal | C57BL/6J mice | 100 mg/kg body weight/day | Resveratrol ameliorates high‑fat diet‑induced insulin resistance via the DDIT4/mTOR pathway in skeletal muscle. |
| high fat diet | Increases - showed significant elevation | plasma total and LDL-cholesterol, triglycerides and phospholipids | Animal | rats | 10 mg/kg body weight per day. | Comparative evaluation of flavone from Mucuna pruriens and coumarin from Ionidium suffruticosum for hypolipidemic activity in rats fed with high fat diet.cited 18× |
| high-fat diet (37% energy from fat and 50% from carbohydrates) | Decreases - significantly decreased | plasma triglycerides | Human | 12 nonobese healthy men with normal plasma lipid profile | High-fat diet (37% energy from fat, 50% from carbohydrates) and low-fat diet (25% energy from fat, 62% from carbohydrates). | Effect of short-term low- and high-fat diets on low-density lipoprotein particle size in normolipidemic subjects.cited 31× |
| high-fat diet | Decreases - reduced plasma triglycerides more | plasma triglycerides | Human | obese adults | 600 kcal energy-deficient diets (low-fat: 20-25% fat; high-fat: 40-45% fat). | Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors.cited 6× |
| low-fat diet with >2 prot% increase | Decreases - showed a triglyceride reduction equally large | triglycerides | Human | participants on a low-fat diet who had increased the percentage energy intake from protein | 600 kcal energy-deficient diets (low-fat: 20-25% fat; high-fat: 40-45% fat). | Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors.cited 6× |
| high fat diet (HFD) | Increases - greater than | serum triglycerides | Animal | obese control female rats (OFR) | 5 and 10 mg/kg/day. | Saponin-rich extract of Tribulus terrestris alleviates systemic inflammation and insulin resistance in dietary obese female rats: Impact on adipokine/hormonal disturbances.cited 6× |
| High fat diet (HFD) (20 g/day) | Increases - were enhanced significantly | serum triglycerides | Animal | Wistar rats | 200 mg/kg orally per day | Evaluation of antiobesity and cardioprotective effect of Gymnema sylvestre extract in murine model.cited 23× |
| high-fat diet | Increases - significantly elevated | some triglycerides | Animal | obese rats | Not specified | [Effect of guarana on lipid metabolism in obese rats: a study based on lipidomics]. |
| high fat diet (HFD) | Increases - significantly increased | Triglycerides (TG) | Animal | obese rats | Not specified | Effect of caffeine-chitosan nanoparticles and α-lipoic acid on the cardiovascular changes induced in rat model of obesity.cited 5× |
| high fat diet | Increases - significantly increased | triglycerides | Animal | Wistar albino rats | — | Antihyperlipidemic Activity of Aloe succotrina in Rats: Possibly Mediated by Inhibition of HMG-CoA Reductase. |
| high-fat diet (HFD) | Increases - significantly higher | triglycerides (TG) | Animal | Rats (Group 2) | — | Effects of Honey on Postprandial Hyperlipidemia and Oxidative Stress in Wistar Rats: Role of HMG-CoA Reductase Inhibition and Antioxidant Effect. |
| very low-calorie ketogenic diet (VLCKD) | Decreases - showed slightly less metabolic improvement | triglycerides | Human | patients with weight regain post-bariatric surgery (BS+) | Not specified | Impact of a very low-calorie ketogenic diet on metabolic and microbiota outcomes in post-bariatric patients and bariatric-Naïve individuals: A comparative pilot study.cited 1× |
| LoGIx diet | Decreases - decreased | triglycerides (TGs) | Human | adults with the metabolic syndrome | Not specified (dietary intervention only, no dosage mentioned). | Exercise training with weight loss and either a high- or low-glycemic index diet reduces metabolic syndrome severity in older adults.cited 40× |
| HiGIx diet | Decreases - decreased | triglycerides (TGs) | Human | adults with the metabolic syndrome | Not specified (dietary intervention only, no dosage mentioned). | Exercise training with weight loss and either a high- or low-glycemic index diet reduces metabolic syndrome severity in older adults.cited 40× |
| rapeseed oil-enriched diet | No effect - remained virtually unchanged | serum triglycerides | Human | healthy subjects | Not specified (used for cooking and as table margarine). | Similar serum lipoprotein cholesterol concentrations in healthy subjects on diets enriched with rapeseed and with sunflower oil.cited 17× |
| sunflower oil-enriched diet | No effect - remained virtually unchanged | serum triglycerides | Human | healthy subjects | Not specified (used for cooking and as table margarine). | Similar serum lipoprotein cholesterol concentrations in healthy subjects on diets enriched with rapeseed and with sunflower oil.cited 17× |
| LCn-3PUFA (fish oil) supplementation combined with a reduced energy diet | Decreases - reduced | triglycerides | Human | fish oil group | 6 × 1 g capsules/day of fish oil (LCn-3PUFA). | Dietary supplementation with long chain omega-3 polyunsaturated fatty acids and weight loss in obese adults.cited 38× |
| low-calorie lacto-ovo vegetarian diet | Decreases - significant differences | triglycerides | Human | overweight omnivores with a low-to-moderate cardiovascular risk profile | Not specified (low-calorie diets). | Low-Calorie Vegetarian Versus Mediterranean Diets for Reducing Body Weight and Improving Cardiovascular Risk Profile: CARDIVEG Study (Cardiovascular Prevention With Vegetarian Diet).cited 132× |
| monounsaturated enriched sunflower oil (MO) diet | No effect - were not significantly different | triglycerides | Human | Fourteen healthy males 35 to 55 years of age and 14 healthy postmenopausal women 50 to 60 years of age | 40-42% of energy from fat (26-28% from monounsaturated fat) in the sunflower oil diet. | Effects of monounsaturated enriched sunflower oil on CHD risk factors including LDL size and copper-induced LDL oxidation.cited 13× |
| high-monounsaturated fatty acid (MUFA) diet | No effect - were similar | total triglycerides | Human | free-living individuals with Type 2 diabetes mellitus | MUFA diet (40% energy from fat, primarily virgin olive oil). | Comparison of a high-carbohydrate and a high-monounsaturated fat, olive oil-rich diet on the susceptibility of LDL to oxidative modification in subjects with Type 2 diabetes mellitus.cited 50× |
| high-carbohydrate (CHO) diet | No effect - were similar | total triglycerides | Human | free-living individuals with Type 2 diabetes mellitus | MUFA diet (40% energy from fat, primarily virgin olive oil). | Comparison of a high-carbohydrate and a high-monounsaturated fat, olive oil-rich diet on the susceptibility of LDL to oxidative modification in subjects with Type 2 diabetes mellitus.cited 50× |
| low-fat, high-carbohydrate, low-glycaemic index diet (HC) combined with aerobic/resistance exercise | Increases - changes in triglycerides | triglycerides | Human | overweight and obese patients with type 2 diabetes (T2D) | HC diet: 53% carbohydrate, 17% protein, 30% fat (<10% saturated fat), energy-matched and hypocaloric. | Effects of an energy-restricted low-carbohydrate, high unsaturated fat/low saturated fat diet versus a high-carbohydrate, low-fat diet in type 2 diabetes: A 2-year randomized clinical trial.cited 125× |
| low-carbohydrate, high-unsaturated/low-saturated fat diet (LC) combined with aerobic/resistance exercise | Decreases - greater reductions in triglycerides | triglycerides | Human | overweight and obese patients with type 2 diabetes (T2D) | HC diet: 53% carbohydrate, 17% protein, 30% fat (<10% saturated fat), energy-matched and hypocaloric. | Effects of an energy-restricted low-carbohydrate, high unsaturated fat/low saturated fat diet versus a high-carbohydrate, low-fat diet in type 2 diabetes: A 2-year randomized clinical trial.cited 125× |
| LC and high saturated fat diet (LCHS) | Decreases - fully mediated the effects | triglycerides | Human | adults aged 45-80 years from the UK National Diet and Nutrition Survey programme | Not specified | Do markers of adiposity and glycaemia mediate the association between low carbohydrate diet and cardiovascular risk factors: findings from the UK National Diet and Nutrition Survey (NDNS) 2008-2016. |
| Low carbohydrate (LC) and high fibre diet (LCHF) | No effect - were not sufficient to fully mediate the effects | triglycerides | Human | adults aged 45-80 years from the UK National Diet and Nutrition Survey programme | Not specified | Do markers of adiposity and glycaemia mediate the association between low carbohydrate diet and cardiovascular risk factors: findings from the UK National Diet and Nutrition Survey (NDNS) 2008-2016. |
| low carbohydrate diet (LCD) | Decreases - fully mediated the association | triglycerides | Human | adults aged 45-80 years from the UK National Diet and Nutrition Survey programme | Not specified | Do markers of adiposity and glycaemia mediate the association between low carbohydrate diet and cardiovascular risk factors: findings from the UK National Diet and Nutrition Survey (NDNS) 2008-2016. |
| fructose diet | Increases - increased | plasma triglycerides (TGs) | Animal | male Sprague Dawley rats | 1 g · kg(-1) · d(-1) | Citrulline and Nonessential Amino Acids Prevent Fructose-Induced Nonalcoholic Fatty Liver Disease in Rats.cited 29× |
| Kefir milk + high-fat diet | Decreases - corrected | Triglycerides | Animal | adult rats | 1 ml/100 g body weight of Kefir milk | Kefir milk consumption decreases sperm alterations due to the high-fat diet in adult male rats.cited 2× |
| HF, high-energy diet of 3 days | Decreases - reduced | triglycerides | Human | eleven male volunteers | Not specified (HF yogurt supplement used). | Gastrointestinal transit, post-prandial lipaemia and satiety following 3 days high-fat diet in men.cited 20× |
| Ideal Protein (IP) system Phase I diet | Decreases - significant between-group differences in change | triglycerides (TG) | Human | adults with obesity | <30% of daily energy from fat, <7% from saturated fat, 55% from carbohydrate, and an energy deficit of 500 kcal/day. | Effect of ideal protein versus low-fat diet for weight loss: A randomized controlled trial.cited 4× |
| Whole Food Plant-based (WFPB) diet | Decreases - led to significant decreases | triglycerides | Human | participants referred to a "Food as Prevention" program | Not specified | Implementation of a Whole Food Plant Based Diet in a Food as Prevention Program in a Resource Constrained Environment.cited 2× |
| high-carbohydrate diet (Precitene Diabet) | Increases - increased | mean weekly blood triglycerides levels | Human | type 2 diabetes patients admitted to the hospital for neurologic disorders or head and neck cancer surgery | Not specified | Glycemic and lipid control in hospitalized type 2 diabetic patients: evaluation of 2 enteral nutrition formulas (low carbohydrate-high monounsaturated fat vs high carbohydrate).cited 35× |
| low-carbohydrate-high-mono-unsaturated-fat (Glucerna) diet | No effect - showed a stable trend | mean weekly blood triglycerides levels | Human | type 2 diabetes patients admitted to the hospital for neurologic disorders or head and neck cancer surgery | Not specified | Glycemic and lipid control in hospitalized type 2 diabetic patients: evaluation of 2 enteral nutrition formulas (low carbohydrate-high monounsaturated fat vs high carbohydrate).cited 35× |
| higher protein diet (HPD) | Decreases - demonstrated significant decreases | triglycerides | Human | Mexican adults with MeS | 1.34 g/kg body weight (HPD) vs. 0.8 g/kg body weight (SPD). | Effect of a High-Protein Diet versus Standard-Protein Diet on Weight Loss and Biomarkers of Metabolic Syndrome: A Randomized Clinical Trial.cited 59× |
| standard protein diet (SPD) | Decreases - demonstrated significant decreases | triglycerides | Human | Mexican adults with MeS | 1.34 g/kg body weight (HPD) vs. 0.8 g/kg body weight (SPD). | Effect of a High-Protein Diet versus Standard-Protein Diet on Weight Loss and Biomarkers of Metabolic Syndrome: A Randomized Clinical Trial.cited 59× |
| high-fat, high fructose diet (HFFD) | Increases - increased | triglycerides | Animal | offspring | 50 mg/kg FA daily. | Ferulic acid protects rat offspring from maternal high-fat, high-fructose diet-induced toxicity and developmental retardation through a direct effect on pancreatic islets. |
| moderate aerobic exercise training in addition to diet regimen | Decreases - significantly decreased | Triglycerides (TG) | Human | obese patients with NASH | Not specified (intervention involved moderate aerobic exercise and diet regimen). | Biochemical parameters response to weight loss in patients with non-alcoholic steatohepatitis.cited 17× |
| 12-week energy-restricted diet intervention | Decreases - decreased significantly | triglycerides | Human | MAO women | Not specified (intervention was an energy-restricted diet, not alanine supplementation). | A weight loss diet intervention has a similar beneficial effect on both metabolically abnormal obese and metabolically healthy but obese premenopausal women.cited 31× |
| low-glycemic index (GI) diet | No effect - did not show important differences | total cholesterol triglycerides | Human | subjects with well-controlled non-insulin-dependent diabetes mellitus (NIDDM) and normal lipid profile | Not specified (diets were matched for macronutrient composition and fiber). | Low-glycemic index foods improve long-term glycemic control in NIDDM.cited 209× |
| Western-diet (WD) | Increases - increased | hepatic triglycerides | Animal | female ovariectomized (OVX) ApoE KO mice | Not specified for Western Diet; estradiol dosage not detailed. | Estradiol Protects Female ApoE KO Mice against Western-Diet-Induced Non-Alcoholic Steatohepatitis.cited 6× |
| Western-diet (WD) | Increases - increased | plasma triglycerides | Animal | female ovariectomized (OVX) ApoE KO mice | Not specified for Western Diet; estradiol dosage not detailed. | Estradiol Protects Female ApoE KO Mice against Western-Diet-Induced Non-Alcoholic Steatohepatitis.cited 6× |
| Omega-3 fatty acids (OM3-FAs) with a low-fat diet | Decreases - are recommended | triglycerides and acute pancreatitis (AP) risk | Human | patients with severe hypertriglyceridemia (SHTG) | OM3-CA (2 g or 4 g) and OM3-EE (4 g) once daily. | Omega-3 fatty acid exposure with a low-fat diet in patients with past hypertriglyceridemia-induced acute pancreatitis; an exploratory, randomized, open-label crossover study.cited 5× |
| fasting mimicking diet (FMD) | Decreases - decreased | serum triglycerides | Human | patients with MASLD | 30 g/day of flaxseed powder. | Effectiveness of flaxseed consumption and fasting mimicking diet on anthropometric measures, biochemical parameters, and hepatic features in patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): a randomized controlled clinical trial.cited 2× |
| soy foods diet | No effect - showed no significant differences | triglycerides | Human | postmenopausal women | Diets were equivalent in energy, protein, and fat, with at least 80% of protein from dairy. | The effect of dietary protein source on serum lipids: Secondary data analysis from a randomized clinical trial.cited 6× |
| nonsoy plant-based diet | No effect - showed no significant differences | triglycerides | Human | postmenopausal women | Diets were equivalent in energy, protein, and fat, with at least 80% of protein from dairy. | The effect of dietary protein source on serum lipids: Secondary data analysis from a randomized clinical trial.cited 6× |
| nondairy animal protein diet | No effect - showed no significant differences | triglycerides | Human | postmenopausal women | Diets were equivalent in energy, protein, and fat, with at least 80% of protein from dairy. | The effect of dietary protein source on serum lipids: Secondary data analysis from a randomized clinical trial.cited 6× |
| dairy protein diet | No effect - showed no significant differences | triglycerides | Human | postmenopausal women | Diets were equivalent in energy, protein, and fat, with at least 80% of protein from dairy. | The effect of dietary protein source on serum lipids: Secondary data analysis from a randomized clinical trial.cited 6× |
| low-protein diet (LPD) plus inulin | Decreases - lower | triglycerides | Human | CKD patients | LPD (0.6 g/kg/day) plus inulin (19 g/day) for the intervention group; LPD alone for controls. | Prebiotic Therapy with Inulin Associated with Low Protein Diet in Chronic Kidney Disease Patients: Evaluation of Nutritional, Cardiovascular and Psychocognitive Parameters.cited 16× |
| low carbohydrate/high fat (LCHF) diet | No effect - did not differ | plasma levels of triglycerides | Human | young and healthy adults | Less than 20g carbohydrates per day. | Effect of low carbohydrate high fat diet on LDL cholesterol and gene expression in normal-weight, young adults: A randomized controlled study.cited 63× |
| weaning ARA + DHA diet | No effect - without affecting the percentage | ARA in ileum phospholipids and triglycerides | Animal | offspring of allergy-prone Brown Norway dams | Suckling (0.45% ARA, 0.8% DHA); weaning (0.5% ARA, 0.5% DHA). | Feeding Docosahexaenoic Acid and Arachidonic Acid during Suckling and Weaning Contributes to Oral Tolerance Development by Beneficially Modulating the Intestinal Cytokine and Immunoglobulin Levels in an Allergy-Prone Brown Norway Rat Model. |
| weaning ARA + DHA diet | Increases - resulted in a higher percentage | DHA in ileum triglycerides | Animal | offspring of allergy-prone Brown Norway dams | Suckling (0.45% ARA, 0.8% DHA); weaning (0.5% ARA, 0.5% DHA). | Feeding Docosahexaenoic Acid and Arachidonic Acid during Suckling and Weaning Contributes to Oral Tolerance Development by Beneficially Modulating the Intestinal Cytokine and Immunoglobulin Levels in an Allergy-Prone Brown Norway Rat Model. |
| portfolio Moderate-carbohydrate diet (PMCD) | Decreases - improved more in the PMCD compared to the KD | triglycerides | Human | overweight or obese women with PCOS | 70% fat content in the ketogenic diet (specific amounts not detailed). | The effects of portfolio moderate-carbohydrate and ketogenic diets on anthropometric indices, metabolic status, and hormonal levels in overweight or obese women with polycystic ovary syndrome: a randomized controlled trial. |
| ketogenic diet (KD) | Decreases - reducing | blood triglycerides | Animal | ZSF1 Obese heart failure with preserved ejection fraction (HFpEF) phenotype | Not specified for the ketogenic diet; ketone salts were added to drinking water (exact dosage not provided). | Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model.cited 1× |
| ketogenic diet (KD) | Decreases - decreases | triglycerides | Human | humans | Not Assessed | Novel Nutritional and Dietary Approaches to Weight Loss for the Prevention of Cardiovascular Disease: Ketogenic Diet, Intermittent Fasting, and Bariatric Surgery.cited 8× |
| ketogenic diet (KD) | Increases - triglycerides (TG) increased slightly | triglycerides (TG) | Human | 23 obese adult women | Not specified (participants followed a typical 7-day meal plan with flexibility). | Effect of Low-Carbohydrate Diet on Beta-Hydroxybutyrate Ketogenesis Metabolic Stimulation and Regulation of NLRP3 Ubiquitination in Obese Saudi Women.cited 2× |
| ketogenic diet (KD) | Decreases - significantly decreased | triglycerides levels | Human | women diagnosed with PCOS | Not specified | The effects of ketogenic diet on metabolic and hormonal parameters in patients with polycystic ovary syndrome: a systematic review and meta-analysis of clinical trials.cited 1× |
| moderate high fat diet (HFD) | Decreases - lower accumulation of | liver triglycerides | Animal | Sprague-Dawley rats | — | Regulation of hepatic mitochondrial metabolism in response to a high fat diet: a longitudinal study in rats. |
| gluten-free diet | No effect - significant changes not consistently reported | triglycerides | Human | patients with celiac disease | Not Assessed | Effect of the gluten-free diet on cardiovascular risk factors in patients with coeliac disease: A systematic review.cited 55× |
| gluten-free diet (GFD) | Decreases - greater decrease | triglycerides levels | Human | the youngest children with T1DM and CD | Not specified | Whole lipid profile and not only HDL cholesterol is impaired in children with coexisting type 1 diabetes and untreated celiac disease.cited 16× |
| milk-based ketogenic diet (KD) | No effect - showed no significant changes | triglycerides | Human | infants with genetic DRE | KD started at a 2:1 ratio based on a non-fasting protocol, optimized as needed. | Breaking Myths: The Underexplored Impact of the Ketogenic Diet on Managing Drug-Resistant Epilepsy in Infancy. |
| low-fat diet (LFD) | Increases - improved | total cholesterol, HDL-cholesterol, triglycerides | Human | patients over 35 years with chronic hepatitis C with BMI over 25 kg/m² | Not specified (dietary interventions only). | Effects of lifestyle changes including specific dietary intervention and physical activity in the management of patients with chronic hepatitis C--a randomized trial.cited 18× |
| normoglucidic low-calorie diet (NGLCD) | Increases - improved | total cholesterol, HDL-cholesterol, triglycerides | Human | patients over 35 years with chronic hepatitis C with BMI over 25 kg/m² | Not specified (dietary interventions only). | Effects of lifestyle changes including specific dietary intervention and physical activity in the management of patients with chronic hepatitis C--a randomized trial.cited 18× |
| low-fat diet | No effect - no statistically significant differences | triglycerides (TG) | Human | two groups | Not specified | Effects of low-fat diet on serum lipids in premenopausal and postmenopausal women: a meta-analysis of randomized controlled trials.cited 15× |
| DF diet | No effect - did not reduce | triglycerides | Human | hyperlipidaemic subjects | Not specified | Replacing dairy fat with rapeseed oil causes rapid improvement of hyperlipidaemia: a randomized controlled study.cited 58× |
| RO diet | Decreases - reduced | triglycerides | Human | hyperlipidaemic subjects | Not specified | Replacing dairy fat with rapeseed oil causes rapid improvement of hyperlipidaemia: a randomized controlled study.cited 58× |
| High-caloric diet | Increases - increased | fasting serum triglycerides | Animal | male Wistar rats | 60 mg/kg/day (containing 12.48% aspalathin). | Cardioprotective Function of Green Rooibos (Aspalathus linearis) Extract Supplementation in Ex Vivo Ischemic Prediabetic Rat Hearts.cited 4× |
| energy-restricted anti-inflammatory diet | Decreases - reducing | triglycerides | Human | younger adults with obesity | Not specified | Metabolic and Hepatic Effects of Energy-Reduced Anti-Inflammatory Diet in Younger Adults with Obesity.cited 16× |
| ketogenic Mediterranean diet with phyoextracts (KEMEPHY) | Decreases - significant decrease | triglycerides | Human | overweight women with diagnosis of PCOS | Not specified (ketogenic Mediterranean diet with phyoextracts). | Effects of a ketogenic diet in overweight women with polycystic ovary syndrome.cited 148× |
| VLCFA-restricted Mediterranean diet | Decreases - significantly lower | triglycerides | Human | compliant adult patients | Not specified | Nutritional Counseling and Mediterranean Diet in Adrenoleukodystrophy: A Real-Life Experience.cited 2× |
| low-calorie diet (LCD) | Decreases - led to a significant decrease | serum triglycerides | Human | 52 patients with MAFLD | 16:8 IF (time-restricted feeding window, exact calorie intake not specified). | The Effect of Intermittent Fasting Diet in Comparison With Low-Calorie Diet on Inflammation, Lipid Profile, Glycemic Index, Liver Fibrosis in Patients With Metabolic-Associated Fatty Liver Disease (MAFLD): A Randomized Controlled Trial. |
| modified-fat diet high in monounsaturated fat | No effect - were not significantly different | triglycerides | Human | Thirty healthy, free-living, nonsmoking men and women from the Melbourne, Australia, metropolitan region | Not specified | Diet high in monounsaturated fat does not have a different effect on arterial elasticity than a low-fat, high-carbohydrate diet.cited 11× |
| vegan diet | Decreases - lowers | triglycerides | Human | 21 (11 female,10 male) healthy participants | Individual caloric needs met; exact amounts not specified. | A 48-Hour Vegan Diet Challenge in Healthy Women and Men Induces a BRANCH-Chain Amino Acid Related, Health Associated, Metabolic Signature.cited 24× |
| high-fat high-fructose diet (HFHFD) | Increases - increased | plasma triglycerides | Animal | rats | Not specified | A Combined GLP-1/PPARa/CB1-Based Therapy to Restore the Central and Peripheral Metabolic Dysregulation Induced by a High-Fructose High-Fat Diet. |
| a normocaloric low n-6:n-3 PUFA ratio diet | Decreases - reduction | triglycerides | Human | obese youth 9-19 y of age with nonalcoholic fatty liver disease | Not specified (normocaloric diet with n-6:n-3 PUFA ratio of 4:1). | A Low ω-6 to ω-3 PUFA Ratio (n-6:n-3 PUFA) Diet to Treat Fatty Liver Disease in Obese Youth.cited 58× |
| Mediterranean-style low-glycemic-load diet | Decreases - decreases | plasma triglycerides | Human | women with metabolic syndrome and elevated plasma LDL cholesterol | — | A Mediterranean-style, low-glycemic-load diet reduces the expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in mononuclear cells and plasma insulin in women with metabolic syndrome. |
| low-carbohydrate high-fat (LCHF) diet | Decreases - reduced | Triglycerides | Human | subjects with type 2 diabetes | Not specified | Comprehensive analysis of systemic, metabolic, and molecular changes following prospective change to low-carbohydrate diet in adults with type 2 diabetes mellitus in India. |
| low-carbohydrate high-fat (LCHF) diet | Decreases - reduced | Triglycerides | Human | subjects with type 2 diabetes | Not specified | Comprehensive analysis of systemic, metabolic, and molecular changes following prospective change to low-carbohydrate diet in adults with type 2 diabetes mellitus in India. |
| healthy Nordic diet (HND) | Decreases - associated with | triglycerides | Human | participants with metabolic syndrome | Not specified (dietary advice included low-fat dairy as part of the Nordic diet). | Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids.cited 14× |
| healthy Nordic diet (HND) | Increases - related with | triglycerides | Human | participants with metabolic syndrome | Not specified (dietary advice included low-fat dairy as part of the Nordic diet). | Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids.cited 14× |
| diet supplementation with 20% of Bravo de Esmolfe apple cultivar | Decreases - decrease significantly | serum levels of triglycerides | Animal | male Wistar rats fed a cholesterol-enriched diet (2%) | Diet supplemented with 20% of apple cultivars (Bravo de Esmolfe, Malápio Serra, and Golden). | Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition.cited 40× |
| low-saturated-fat diet | Decreases - reduction | serum triglycerides | Human | Subjects with MetS | Not specified | Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome.cited 85× |
| Weight loss either with diet or antiobestic medication | Decreases - induces the decrease | triglycerides (TG) | Human | — | Not specified | Obesity and Dyslipidemia.cited 64× |
| low-protein diet supplemented with ketoacids | Increases - mean change score in triglycerides | triglycerides | Human | predialysis CKD patients | Not specified | Optimizing Nutrition in Renal Patients: Effects of a Low-Protein Diet Supplemented With Ketoacids.cited 1× |
| a moderately low-carbohydrate diet | Decreases - decrease | triglycerides | Human | participants with abnormal baseline values | Not specified | Changes in Body Weight, Dysglycemia, and Dyslipidemia After Moderately Low-Carbohydrate Diet Education (LOCABO Challenge Program) Among Workers in Japan.cited 3× |
| Mediterranean diet in association with Realsil complex | No effect - significant variation | triglycerides | Human | overweight patients with non-alcoholic fatty liver disease | Daily administration of Realsil complex (specific dosage not provided). | Effects of Mediterranean diet supplemented with silybin-vitamin E-phospholipid complex in overweight patients with non-alcoholic fatty liver disease.cited 56× |
| Mediterranean diet | No effect - significant variation | triglycerides | Human | overweight patients with non-alcoholic fatty liver disease | Daily administration of Realsil complex (specific dosage not provided). | Effects of Mediterranean diet supplemented with silybin-vitamin E-phospholipid complex in overweight patients with non-alcoholic fatty liver disease.cited 56× |
| fast food diet (FFD) | No effect - group by time interaction was not significant for TGs | triglycerides (TGs) | Animal | C57BL/6 J mice | Not specified (fast food diet composition not detailed). | Partial validation of a six-month high-fat diet and fructose-glucose drink combination as a mouse model of nonalcoholic fatty liver disease.cited 3× |
| leucine-rich diet | No effect - observed no changes | triglycerides concentrations | Animal | Rats | — | Leucine improves protein nutritional status and regulates hepatic lipid metabolism in calorie-restricted rats. |
| PUFA-rich corn oil diet | Decreases - were significantly lower | total triglycerides (TG) | Human | 28 healthy, non-smoking young men aged between 19 and 31 years | 12 g sunflower oil/day (as part of a 68 g olive oil + 12 g sunflower oil mixture). | Impact of diets containing corn oil or olive/sunflower oil mixture on the human plasma and lipoprotein lipid metabolism.cited 30× |
| low-carb diet | Decreases - stronger decrease | triglycerides (TG) levels | Human | subjects with prediabetes | Not specified. | Liver Fat Scores Moderately Reflect Interventional Changes in Liver Fat Content by a Low-Fat Diet but Not by a Low-Carb Diet.cited 24× |
| multibotanical plus soy diet counseling | No effect - no statistically significant differences in the adjusted mean change | triglycerides | Human | peri or post-menopausal women experiencing vasomotor symptoms | 160 mg daily (Black Cohosh alone) or 200 mg daily (in multibotanical). | The effects of black cohosh therapies on lipids, fibrinogen, glucose and insulin.cited 18× |
| high-sucrose/low-fat diet | Increases - increased | serum triglycerides | Animal | mice with impaired mitochondrial metabolism | — | Opposing effects of dietary sugar and saturated fat on cardiovascular risk factors and glucose metabolism in mitochondrially impaired mice. |
| recreational football training combined with calorie-restricted diet | Decreases - reductions in | blood triglycerides | Human | type 2 diabetes (T2D) patients | — | Positive effects of football on fitness, lipid profile, and insulin resistance in Brazilian patients with type 2 diabetes.cited 58× |
| programmed diet | Decreases - significant reduction | serum total cholesterol (TC), triglycerides (TG) and low-density-lipoprotein cholesterol (LDLC) | Human | subjects with grade-1 essential hypertension | 10 mg monacolin K daily (one tablet per day). | The short-term supplementation of monacolin K improves the lipid and metabolic patterns of hypertensive and hypercholesterolemic subjects at low cardiovascular risk.cited 12× |
| high-sucrose diet (HSD) | Increases - significant increase | triglycerides (TG) | Animal | fruit flies | — | Novel ketogenic diet formulation improves sucrose-induced insulin resistance in canton strain Drosophila melanogaster. |
| exercise combined with high-protein diet | Decreases - had lower triglycerides | triglycerides | Human | middle-aged adults with obesity | Not specified | Effects of Combined High-Protein Diet and Exercise Intervention on Cardiometabolic Health in Middle-Aged Obese Adults: A Randomized Controlled Trial.cited 7× |
| beef tallow diet | Decreases - declined steadily | Plasma triglycerides | Animal | tallow-fed pigs | 10 g/100 g of diet (HOSO or beef tallow). | Lipid metabolism in pigs fed beef tallow or high-oleic acid sunflower oil.cited 31× |
| weight-loss diet-induced decreases in primary BAs | Decreases - were related to larger reductions | triglycerides | Human | adults with overweight or obesity | Not specified. | Changes in bile acid subtypes and improvements in lipid metabolism and atherosclerotic cardiovascular disease risk: the Preventing Overweight Using Novel Dietary Strategies (POUNDS Lost) trial.cited 2× |
| time-restricted feeding (TRF; 16/8) with a Lacto-Ovo-Vegetarian (LOV) diet | Decreases - improved with a reduction | triglycerides | Human | overweight and obese patients with MAFLD | Time-restricted feeding (16/8 protocol) combined with a Lacto-Ovo-Vegetarian diet. | Effects of time restricted feeding combined with Lacto Ovo vegetarian diet on metabolic associated fatty liver disease management: a randomized clinical trial. |
| DASH diet | Decreases - positive relationship | lower serum levels of triglycerides | Human | adults from 27 counties of Khuzestan province, Iran | Not specified | The Association between DASH Diet Adherence and Cardiovascular Risk Factors.cited 8× |
| DASH diet | Decreases - decreased | serum triglycerides | Human | overweight and obese women with polycystic ovary syndrome (PCOS) | Not specified (diet composition: 52% carbohydrates, 18% proteins, 30% total fats, with DASH emphasizing fruits, vegetables, whole grains, and low-fat dairy). | Effects of DASH diet on lipid profiles and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: a randomized clinical trial.cited 93× |
| DASH diet | Decreases - led to a significant reduction | triglycerides | Human | overweight and obese women with polycystic ovary syndrome (PCOS) | Not specified (diet composition: 52% carbohydrates, 18% proteins, 30% total fats, with DASH emphasizing fruits, vegetables, whole grains, and low-fat dairy). | Effects of DASH diet on lipid profiles and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: a randomized clinical trial.cited 93× |
| DASH diet | Decreases - resulted in significant reductions | serum triglycerides | Human | overweight and obese patients with NAFLD | Not specified (dietary pattern, not isolated dairy intake). | The effects of DASH diet on weight loss and metabolic status in adults with non-alcoholic fatty liver disease: a randomized clinical trial.cited 162× |
| Western diet high-fat meal | Increases - were higher after | Triglycerides | Human | older adults with an increased CVD risk | 30 minutes of walking at 4.6 ± 0.1 km/h post-meal. | Moderate Postmeal Walking Has No Beneficial Effects Over Resting on Postprandial Lipemia, Glycemia, Insulinemia, and Selected Oxidative and Inflammatory Parameters in Older Adults with a Cardiovascular Disease Risk Phenotype: A Randomized Crossover Trial.cited 10× |
| Diet I - high-fat hypocaloric diet | Decreases - decreased | triglycerides | Human | obese subjects | Not specified | Impact of 2 Different Hypocaloric Diets on Serum Omentin Levels in Obese Subjects.cited 6× |
| Diet II - low fat hypocaloric diet | Decreases - decreased | triglycerides | Human | obese subjects | Not specified | Impact of 2 Different Hypocaloric Diets on Serum Omentin Levels in Obese Subjects.cited 6× |
| aerobic exercise combined with a prudent diet | Decreases - Statistically significant intervention minus control reductions were found | triglycerides (TG) | Human | adults | Diet recommendations: saturated/trans fat intake <10% of total calories, cholesterol <300 mg/day, fiber ≥25 g/day (women) or ≥35 g/day (men). | Efficacy of aerobic exercise and a prudent diet for improving selected lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials.cited 34× |
| aerobic exercise combined with a prudent diet | Decreases - Changes were equivalent to reductions of | triglycerides (TG) | Human | adults | Diet recommendations: saturated/trans fat intake <10% of total calories, cholesterol <300 mg/day, fiber ≥25 g/day (women) or ≥35 g/day (men). | Efficacy of aerobic exercise and a prudent diet for improving selected lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials.cited 34× |
| low-glycemic index, low-carbohydrate diet | Decreases - lower | triglycerides | Human | overweight adults | Four diets varying in glycemic index (40% or 65%) and carbohydrate content (40% or 58% of energy). | Effects of high vs low glycemic index of dietary carbohydrate on cardiovascular disease risk factors and insulin sensitivity: the OmniCarb randomized clinical trial.cited 151× |
| Paleolithic diet plus supervised exercise training 3 hours per week | Decreases - showed significant decreases | myocardial triglycerides levels | Human | overweight and obese subjects with type 2 diabetes mellitus | Not specified (dietary intervention only, no dosage mentioned). | Exercise Training Adds Cardiometabolic Benefits of a Paleolithic Diet in Type 2 Diabetes Mellitus.cited 16× |
| Exercise training plus a Paleolithic diet | Decreases - reduced | myocardial triglycerides levels | Human | overweight/obese subjects with type 2 diabetes mellitus | Not specified (dietary intervention only, no dosage mentioned). | Exercise Training Adds Cardiometabolic Benefits of a Paleolithic Diet in Type 2 Diabetes Mellitus.cited 16× |
| Paleolithic diet and standard-care exercise recommendations | No effect - unchanged | myocardial triglycerides levels | Human | overweight and obese subjects with type 2 diabetes mellitus | Not specified (dietary intervention only, no dosage mentioned). | Exercise Training Adds Cardiometabolic Benefits of a Paleolithic Diet in Type 2 Diabetes Mellitus.cited 16× |
| portfolio diet | No effect - No difference was seen in | serum triglycerides | Human | Twenty-five hyperlipidemic subjects | 16.6 g of almonds per 1,000 kcal | The effect of combining plant sterols, soy protein, viscous fibers, and almonds in treating hypercholesterolemia.cited 74× |
| 5:2 diet | No effect - no significant difference | triglycerides | Human | overweight and obese individuals | Not specified (5:2 diet protocol—2 fasting days per week). | Effect of the 5:2 Diet on Weight Loss and Cardiovascular Disease Risk Factors in Overweight and/or Obesity: A Systematic Review and Meta-Analysis. |
| Mediterranean style diet (MSD) | Decreases - significantly decrease | triglycerides (TG) | Human | children and adolescents with obesity | Not specified (diet composition: 60% carbohydrate, 25% fat, 15% protein, rich in polyunsaturated fatty acids, fiber, flavonoids, and antioxidants). | Mediterranean-style diet reduces metabolic syndrome components in obese children and adolescents with obesity.cited 120× |
| Mediterranean diet (MedDiet) | Decreases - reduced | triglycerides | Human | Australian patients post coronary event | Ad libitum (no specific dosage provided). | Ad libitum Mediterranean diet reduces subcutaneous but not visceral fat in patients with coronary heart disease: A randomised controlled pilot study.cited 23× |
| Mediterranean diet (assessed by MED score) | Decreases - The MED score was inversely associated with triglycerides | triglycerides | Human | subjects from the SU.VI.MAX study | Not specified (adherence assessed via dietary scores from at least three 24-hour records). | Adherence to Mediterranean diet reduces the risk of metabolic syndrome: a 6-year prospective study.cited 140× |
| Mediterranean diet (assessed by MDS) | Decreases - The MDS was negatively associated with triglycerides | triglycerides | Human | subjects from the SU.VI.MAX study | Not specified (adherence assessed via dietary scores from at least three 24-hour records). | Adherence to Mediterranean diet reduces the risk of metabolic syndrome: a 6-year prospective study.cited 140× |
| Mediterranean diet | No effect - remained unchanged | triglycerides | Human | stable patients who experienced coronary events in the previous 2 years | Not specified (red wine included as part of the Mediterranean Diet). | Effects of high adherence to mediterranean or low-fat diets in medicated secondary prevention patients.cited 53× |
| low-fat Therapeutic Lifestyle Changes Diet | No effect - remained unchanged | triglycerides | Human | stable patients who experienced coronary events in the previous 2 years | Not specified (red wine included as part of the Mediterranean Diet). | Effects of high adherence to mediterranean or low-fat diets in medicated secondary prevention patients.cited 53× |
| low-energy, high-protein diet | Decreases - reductions in | triglycerides | Human | obese men with obstructive sleep apnea | Not specified | One-month of a low-energy diet, with no additional effect of high-protein, reduces Obstructive Sleep Apnea severity and improve metabolic parameters in obese males.cited 10× |
| high-monounsaturated-fat diet | Decreases - lower | plasma total triglycerides | Human | people with type 1 diabetes | 17% to 20% of total daily calories from monounsaturated fat. | Impact of a high-monounsaturated-fat diet on lipid profile in subjects with type 1 diabetes.cited 9× |
| high-monounsaturated-fat diet | Decreases - lower | very low-density lipoprotein triglycerides | Human | people with type 1 diabetes | 17% to 20% of total daily calories from monounsaturated fat. | Impact of a high-monounsaturated-fat diet on lipid profile in subjects with type 1 diabetes.cited 9× |
| high-monounsaturated-fat diet | Decreases - lower levels of plasma triglycerides | plasma triglycerides | Human | 10 patients with non-insulin-dependent diabetes mellitus (NIDDM) receiving insulin therapy | High-carbohydrate diet: 60% carbohydrates (47% complex carbohydrates), 25% fat. | Comparison of a high-carbohydrate diet with a high-monounsaturated-fat diet in patients with non-insulin-dependent diabetes mellitus.cited 329× |
| alcohol-MCT 32% diet | Decreases - diminution | triglycerides | Animal | Rats | 16% or 32% of total calories as MCT. | Role of medium-chain triglycerides in the alcohol-mediated cytochrome P450 2E1 induction of mitochondria.cited 34× |
| a low-fat vegetarian diet | Decreases - statistically significant reductions | triglycerides | Human | previously non-vegetarian subjects from a Mediterranean population | A whole lacto-vegetarian diet low in fat (20%) was provided as a full daily menu. | [SHORT TERM EFFECTS ON LIPID PROFILE AND GLYCAEMIA OF A LOW-FAT VEGETARIAN DIET].cited 9× |
| a low-fat vegetarian diet | Decreases - produces favourable and significant decreases | triglycerides | Human | — | A whole lacto-vegetarian diet low in fat (20%) was provided as a full daily menu. | [SHORT TERM EFFECTS ON LIPID PROFILE AND GLYCAEMIA OF A LOW-FAT VEGETARIAN DIET].cited 9× |
| low carbohydrate diet (LCD) intervention | Decreases - led to lower triglycerides | triglycerides | Human | PC patients with biochemical recurrence (BCR) after local treatment | Not specified | Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveals the potential role of ketogenesis to slow tumor growth: a secondary analysis of the CAPS2 diet trial.cited 8× |
| MIND diet | Decreases - were 42% lower | chances of having increased serum triglycerides (TG) | Human | Kurdish adults between the ages of 39 and 53 | Not specified | Associations between adherence to MIND diet and general obesity and lipid profile: A cross-sectional study.cited 15× |
| ketogenic diet protocol with ω-3 supplementation (KDO3) | Decreases - decreased more | triglycerides | Human | KDO3 subjects | Not specified | Effects of n-3 polyunsaturated fatty acids (ω-3) supplementation on some cardiovascular risk factors with a ketogenic Mediterranean diet.cited 52× |
| Spirulina platensis (Cyanobacteriaceae) supplementation combined with local diet | Decreases - significant decrease | triglycerides | Human | HIV-infected antiretroviral-naive patients | Not specified | Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naïve patients in Yaounde-Cameroon: a randomized trial study.cited 29× |
| low-carbohydrate, high-fat diet | Decreases - significantly reduced | triglycerides | Human | at-risk New Zealand Defence Force personnel | Not specified. | A 12-week low-carbohydrate, high-fat diet improves metabolic health outcomes over a control diet in a randomised controlled trial with overweight defence force personnel.cited 17× |
| low-carbohydrate, high-fat diet | Decreases - showed small, possibly to likely beneficial effects | triglycerides | Human | at-risk New Zealand Defence Force personnel | Not specified. | A 12-week low-carbohydrate, high-fat diet improves metabolic health outcomes over a control diet in a randomised controlled trial with overweight defence force personnel.cited 17× |
| low-carbohydrate, high-fat (LCHF) diet | Decreases - lower | triglycerides | Human | participants with T2DM | HCLF diet with 50-60% carbohydrates, 20-30% fats, and 20-25% proteins. | Effect of Calorie-Unrestricted Low-Carbohydrate, High-Fat Diet Versus High-Carbohydrate, Low-Fat Diet on Type 2 Diabetes and Nonalcoholic Fatty Liver Disease : A Randomized Controlled Trial.cited 60× |
| conjugated linoleic acid supplementation (CLA) with a weight loss diet and 400 IU vitamin E | Decreases - were significantly better | triglycerides | Human | obese NAFLD patients | Three 1000 mg softgels of CLA daily, alongside a weight loss diet and 400 IU vitamin E. | Conjugated linoleic acid improves glycemic response, lipid profile, and oxidative stress in obese patients with non-alcoholic fatty liver disease: a randomized controlled clinical trial.cited 25× |
| PUFA-enriched diet | Decreases - was associated with reductions in | triglycerides (TG) | Human | middle-aged men and women with MetS | Participants consumed 3 MUFA-enriched or PUFA-enriched muffins daily, with additional supplementation to ensure 25%-50% increases in dietary fat intake from these sources. | Poly is more effective than monounsaturated fat for dietary management in the metabolic syndrome: The muffin study.cited 27× |
| low-carbohydrate diet (LCD) | No effect - No differences were observed | concentrations of triglycerides | Human | patients with insulin pump-treated type 1 diabetes | ≤50 g/day for the low-carbohydrate diet. | Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study.cited 51× |
| low-carbohydrate diet (< or =20 g/d) | No effect - no diet treatment effect | fasting triglycerides | Human | Healthy, obese adults | High-fat diet: ≤20 g carbohydrates/day; high-carb diet: 55% of total energy intake from carbohydrates. | Lack of suppression of circulating free fatty acids and hypercholesterolemia during weight loss on a high-fat, low-carbohydrate diet.cited 40× |
| low-carbohydrate diet (LCD) | Decreases - significant decreases | plasma triglycerides | Human | 1,141 obese patients | Not specified | Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors.cited 199× |
| low carbohydrate (LC) diet | Decreases - significantly reduced | triglycerides | Human | mostly obese participants with T2D | Not specified | Comparison of the Effectiveness of Low Carbohydrate Versus Low Fat Diets, in Type 2 Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.cited 18× |
| low-carbohydrate diet (LC) | Decreases - significantly reduced | triglycerides | Human | overweight/obese Chinese females | Not specified | Non-Energy-Restricted Low-Carbohydrate Diet Combined with Exercise Intervention Improved Cardiometabolic Health in Overweight Chinese Females.cited 25× |
| low-carbohydrate diet | Decreases - may promote favourable outcomes | triglycerides | Human | adults with type 2 diabetes | Not specified (varied by study). | The interpretation and effect of a low-carbohydrate diet in the management of type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials.cited 113× |
| low-carbohydrate diet (LCD) | Decreases - decreased | triglycerides | Human | adults with overweight or obesity | Carbohydrate intake < 50 g/day | Low-carbohydrate diets lead to greater weight loss and better glucose homeostasis than exercise: a randomized clinical trial.cited 14× |
| low energy diet containing condensed processed yogurt (Kashk) | Decreases - significantly decreased | triglycerides levels | Human | women with overweight/obesity | 50 g of Kashk daily | Effect of a low energy diet, containing a high protein, probiotic condensed yogurt, on biochemical and anthropometric measurements among women with overweight/obesity: A randomised controlled trial.cited 14× |
| high cholesterol diet (HCD) | Increases - significant (p < 0.001) increase | levels of triglycerides (TG) | Animal | rats | Not specified | Lipid-lowering effect of Rhus coriaria L. (sumac) fruit extract in hypercholesterolemic rats.cited 26× |
| high-cholesterol diet (HCD) | Increases - significantly increased | serum triglycerides | Animal | rats | 0.5 mL/kg | The Impact of Dietary Consumption of Palm Oil and Olive Oil on Lipid Profile and Hepatocyte Injury in Hypercholesterolemic Rats.cited 6× |
| fructose-enriched diet | Increases - elevated levels | triglycerides (TG) | Animal | rats | 20% casein diet supplemented with pumpkin protein (exact dosage not specified). | Effects of Pumpkin (Cucurbita pepo L.) Seed Protein on Blood Pressure, Plasma Lipids, Leptin, Adiponectin, and Oxidative Stress in Rats with Fructose-Induced Metabolic Syndrome.cited 1× |