25
87
12
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Evidence suggests Ketogenic Diet maydecreaseTriglyceride levels.
98 studies (124 claims)
Moderate consensus
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| egg-enriched diet | Decreases - had lower | hepatic triglyceride | Animal | Sprague-Dawley rats | — | An egg-enriched diet attenuates plasma lipids and mediates cholesterol metabolism of high-cholesterol fed rats. |
| low-carbohydrate diet interventions lasting less than 6 months | Decreases - were associated with a decrease | triglyceride levels | Human | — | Not specified | The effects of low-carbohydrate diets on cardiovascular risk factors: A meta-analysis.cited 58× |
| low-carbohydrate diet interventions lasting 12-23 months | Decreases - were associated with a decrease | triglyceride levels | Human | — | Not specified | The effects of low-carbohydrate diets on cardiovascular risk factors: A meta-analysis.cited 58× |
| low-carbohydrate diet | Decreases - was associated with a decrease | triglyceride levels | Human | — | Not specified | The effects of low-carbohydrate diets on cardiovascular risk factors: A meta-analysis.cited 58× |
| diet therapy and coconut oil intake | Decreases - decreased significantly | triglyceride (TG) level | Human | overweight individuals | 20 mL of coconut oil per day. | The effect of coconut oil on anthropometric measurements and irisin levels in overweight individuals. |
| Addition of fructose to the diet | Increases - can increase | postprandial plasma triglyceride and uric acid concentration | Human | normal weight and overweight subjects | Participants consumed 3.3 dL of ASB or SSB with meals. | Metabolic Effects of Replacing Sugar-Sweetened Beverages with Artificially-Sweetened Beverages in Overweight Subjects with or without Hepatic Steatosis: A Randomized Control Clinical Trial.cited 8× |
| MCT diet | Decreases - reduced | triglyceride levels | Human | the youngest patient | Not specified | Glycogen storage disease type 1: impact of medium-chain triglycerides on metabolic control and growth.cited 19× |
| BD + Cal diet | Decreases - had lower | total cholesterol and triglyceride concentrations in breast | Animal | Birds | 1% DHA-rich Aurantiochytrium (1.2 g DHA/kg diet) in Exp. 1; 0.33-0.66% DHA-rich oil (1.5-3.0 g DHA/kg diet) in Exp. 2 | Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance, tissue lipid profiles, and tibia characteristics of broiler chickens.cited 2× |
| BD + Cal diet | Decreases - had lower | total cholesterol and triglyceride concentrations in liver | Animal | Birds | 1% DHA-rich Aurantiochytrium (1.2 g DHA/kg diet) in Exp. 1; 0.33-0.66% DHA-rich oil (1.5-3.0 g DHA/kg diet) in Exp. 2 | Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance, tissue lipid profiles, and tibia characteristics of broiler chickens.cited 2× |
| BD + Cal diet | Decreases - had lower | total cholesterol and triglyceride concentrations in plasma | Animal | Birds | 1% DHA-rich Aurantiochytrium (1.2 g DHA/kg diet) in Exp. 1; 0.33-0.66% DHA-rich oil (1.5-3.0 g DHA/kg diet) in Exp. 2 | Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance, tissue lipid profiles, and tibia characteristics of broiler chickens.cited 2× |
| BD + Cal diet | Decreases - had lower | total cholesterol and triglyceride concentrations in thigh | Animal | Birds | 1% DHA-rich Aurantiochytrium (1.2 g DHA/kg diet) in Exp. 1; 0.33-0.66% DHA-rich oil (1.5-3.0 g DHA/kg diet) in Exp. 2 | Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance, tissue lipid profiles, and tibia characteristics of broiler chickens.cited 2× |
| BD + DHA + EPA diet | Decreases - had lower | total cholesterol and triglyceride concentrations in breast | Animal | Birds | 1% DHA-rich Aurantiochytrium (1.2 g DHA/kg diet) in Exp. 1; 0.33-0.66% DHA-rich oil (1.5-3.0 g DHA/kg diet) in Exp. 2 | Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance, tissue lipid profiles, and tibia characteristics of broiler chickens.cited 2× |
| BD + DHA + EPA diet | Decreases - had lower | total cholesterol and triglyceride concentrations in liver | Animal | Birds | 1% DHA-rich Aurantiochytrium (1.2 g DHA/kg diet) in Exp. 1; 0.33-0.66% DHA-rich oil (1.5-3.0 g DHA/kg diet) in Exp. 2 | Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance, tissue lipid profiles, and tibia characteristics of broiler chickens.cited 2× |
| BD + DHA + EPA diet | Decreases - had lower | total cholesterol and triglyceride concentrations in plasma | Animal | Birds | 1% DHA-rich Aurantiochytrium (1.2 g DHA/kg diet) in Exp. 1; 0.33-0.66% DHA-rich oil (1.5-3.0 g DHA/kg diet) in Exp. 2 | Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance, tissue lipid profiles, and tibia characteristics of broiler chickens.cited 2× |
| BD + DHA + EPA diet | Decreases - had lower | total cholesterol and triglyceride concentrations in thigh | Animal | Birds | 1% DHA-rich Aurantiochytrium (1.2 g DHA/kg diet) in Exp. 1; 0.33-0.66% DHA-rich oil (1.5-3.0 g DHA/kg diet) in Exp. 2 | Supranutrition of microalgal docosahexaenoic acid and calcidiol improved growth performance, tissue lipid profiles, and tibia characteristics of broiler chickens.cited 2× |
| low carbohydrate diet (LCD) score | Decreases - associated with significantly lower | triglyceride (TG) concentrations | Human | obese individuals | Not specified (dietary intake assessed via FFQ, LCD score based on deciles of intake). | Low-carbohydrate diet score is associated with improved blood pressure and cardio-metabolic risk factors among obese adults.cited 6× |
| low-carbohydrates diet (LC) | Decreases - exerted significant effects on decreasing | triglyceride level | Human | overweight male patients with drug addiction | Not specified | Effects of an 8-week Baduanjin intervention combined with low-carbohydrates diet among overweight people who struggle with drug addiction.cited 8× |
| flaxseed oil-containing diet | Increases - resulted in significant increases | alpha-LA concentrations in the plasma phospholipid, cholesteryl ester, and triglyceride fractions | Human | healthy male volunteers | Fish oil supplementation: 1.62 g EPA and 1.08 g DHA daily (triglyceride form). | Dietary substitution with an alpha-linolenic acid-rich vegetable oil increases eicosapentaenoic acid concentrations in tissues.cited 187× |
| dietary milled sesame/pumpkin/flax seed mixture added to a habitual diet | Decreases - lowered | triglyceride | Human | hemodialysis patients | 30 g daily (6 g sesame, 6 g pumpkin, 18 g flax seeds). | Effects of dietary milled seed mixture on fatty acid status and inflammatory markers in patients on hemodialysis.cited 19× |
| rumen-protected methionine and lysine (RML) in a low-protein (LP) diet | Decreases - tended to lower the concentrations | plasma triglyceride | Molecular | lambs | Not specified (dietary CP levels: 14.5% for NP, 12.5% for LP, and LP + RML). | Lipid metabolism and m6A RNA methylation are altered in lambs supplemented rumen-protected methionine and lysine in a low-protein diet.cited 9× |
| 1.5% cholesterol with diet | Increases - significant increase | serum triglyceride | Animal | premature male rats (CFG1) | — | L-Carnitine effect on induced hyperlipidemia on premature rats: fertility profile. |
| hypocaloric legume-based DASH diet | Decreases - A reduction in | triglyceride | Human | overweight and obese patients with type 2 diabetes | Not specified | Improvement of glycemic indices by a hypocaloric legume-based DASH diet in adults with type 2 diabetes: a randomized controlled trial.cited 15× |
| hypocaloric DASH diet | Decreases - A reduction in | triglyceride | Human | overweight and obese patients with type 2 diabetes | Not specified | Improvement of glycemic indices by a hypocaloric legume-based DASH diet in adults with type 2 diabetes: a randomized controlled trial.cited 15× |
| new omega-3 fatty acid and medium-chain triglyceride-rich formula diet | Decreases - showed effectiveness in rapidly and safely lowering | plasma triglyceride levels | Human | patients with severe hypertriglyceridemia | Not specified (formula diet composition details not provided). | Successful treatment of severe hypertriglyceridemia with a formula diet rich in omega-3 fatty acids and medium-chain triglycerides.cited 19× |
| whey protein powders (30 g/day) and isocaloric weight-loss diet | Decreases - decreased | triglyceride | Human | obese women | 30 g/day of whey protein powder. | Whey protein supplementation reducing fasting levels of anandamide and 2-AG without weight loss in pre-menopausal women with obesity on a weight-loss diet.cited 16× |
| 1% cholesterol diet | Decreases - significantly decreased | serum triglyceride levels | Animal | male Wistar rats | — | The mechanism of dietary cholesterol effects on lipids metabolism in rats. |
| biofortified kale diet | Decreases - had lower | total cholesterol (TC) and triglyceride (TG) levels | Animal | rats | Biofortified kale enriched with 5,7-diiodo-8-quinolinol (exact dosage not specified) | Comparative Analysis of Iodine Levels, Biochemical Responses, and Thyroid Gene Expression in Rats Fed Diets with Kale Biofortified with 5,7-Diiodo-8-Quinolinol.cited 1× |
| balanced hypocaloric almond-enriched diet (AED) | Decreases - decreased significantly | triglyceride | Human | overweight and obese women with BMI >25 | 50 g of almonds daily. | The effect of almonds on anthropometric measurements and lipid profile in overweight and obese females in a weight reduction program: A randomized controlled clinical trial.cited 47× |
| high-fat diet plus Streptozotocin | No effect - abnormal levels | collagen I, fibronectin, phosphorylated 5'AMP-activated kinase (p-AMPK), adipose triglyceride lipase (p-ATGL), and HMG-CoA reductase (p-HMGCR) | HumanAnimalMolecular | diabetic mice | — | Disulfide-bond A oxidoreductase-like protein protects against ectopic fat deposition and lipid-related kidney damage in diabetic nephropathy. |
| home-delivered diet | Decreases - were found to decrease more significantly | triglyceride | Human | overweight and obese women | Dietary plan composition: 55-60% carbohydrates, 15-20% protein, 25-30% fat. | Which is the best diet to reduce cardiometabolic risk: dietary counseling or home-delivered diet? |
| high-protein low-fat diet (HP-LF, with 30% protein, 50% carbohydrates and 20% fat) | Decreases - decreased to a greater extent | triglyceride (TG) levels | Human | obese volunteers with type 2 diabetes (DM2) | High-protein low-fat diet (30% protein, 50% carbohydrates, 20% fat); low-protein high-fat diet (15% protein, 50% carbohydrates, 35% fat). | A high-protein low-fat diet is more effective in improving blood pressure and triglycerides in calorie-restricted obese individuals with newly diagnosed type 2 diabetes.cited 39× |
| deficient vitamin A diet | No effect - were not significantly different | alcohol induced changes in hepatic triglyceride levels | Animal | mice | Deficient (0 IU/g diet), control (4 IU/g diet), copious (25 IU/g diet). | Modest effect of differential dietary vitamin A intake on the pathogenesis of alcohol-associated liver disease.cited 1× |
| copious vitamin A diet | No effect - were not significantly different | alcohol induced changes in hepatic triglyceride levels | Animal | mice | Deficient (0 IU/g diet), control (4 IU/g diet), copious (25 IU/g diet). | Modest effect of differential dietary vitamin A intake on the pathogenesis of alcohol-associated liver disease.cited 1× |
| low-fat diet management | No effect - can serve as a valuable prognostic indicator | pleural effusion triglyceride level after 2 days | Human | patients undergoing lung surgery and experiencing chylothorax | Not specified | Prognostic significance of Pleural Fluid triglyceride levels based on a low-Fat Diet Management Strategy in patients with Chylothorax following pulmonary resection.cited 2× |
| High fat diet | Increases - increased | mice body weight, epididymal fat, and hepatic triglyceride and cholesterol contents | Animal | mice | — | Histidine and carnosine alleviated hepatic steatosis in mice consumed high saturated fat diet. |
| high-fat-diet (HFD) | Increases - led to significant increases in levels | triglyceride | Animal | mice | Not specified (low-dose treatment mentioned but exact dosage not provided). | Effects of α-Galactooligosaccharides from Chickpeas on High-Fat-Diet-Induced Metabolic Syndrome in Mice.cited 27× |
| high-fat diet (HFD) | Increases - increased | triglyceride-glucose index | Animal | five-week-old female Sprague Dawley rats | Not specified for LFD; high-dose COC (HCOC) and low-dose COC (LCOC) were administered but exact dosages not provided. | High-dose oral contraceptives induce hyperinsulinemia without altering immune activation in diet-induced obesity which persists even following a dietary low-fat diet intervention.cited 1× |
| high-fat diet (HFD) | Increases - exhibited increased | triglyceride levels | Animal | mice | — | Prebiotics modulate the microbiota-gut-brain axis and ameliorate anxiety and depression-like behavior in HFD-fed mice.cited 15× |
| Animal HP diet | Decreases - decreased | triglyceride levels | Human | subjects with obesity and insulin resistance (IR) | Not specified | Effect of the intake of dietary protein on insulin resistance in subjects with obesity: a randomized controlled clinical trial.cited 17× |
| Vegetable HP diet | Decreases - decreased | triglyceride levels | Human | subjects with obesity and insulin resistance (IR) | Not specified | Effect of the intake of dietary protein on insulin resistance in subjects with obesity: a randomized controlled clinical trial.cited 17× |
| carbohydrate-rich (CHO) diet | Decreases - similar lowering effects | triglyceride | Human | first-degree relatives of Type-2 DM patients | 55% of energy from carbohydrates, 30% from fat, 15% from protein (CHO diet). | Comparison of the effects of a monounsaturated fat diet and a high carbohydrate diet on cardiovascular risk factors in first degree relatives to type-2 diabetic subjects.cited 25× |
| diet rich in olive oil (MUFA diet) | Decreases - similar lowering effects | triglyceride | Human | first-degree relatives of Type-2 DM patients | 55% of energy from carbohydrates, 30% from fat, 15% from protein (CHO diet). | Comparison of the effects of a monounsaturated fat diet and a high carbohydrate diet on cardiovascular risk factors in first degree relatives to type-2 diabetic subjects.cited 25× |
| Mediterranean-type diet (MetD) | Decreases - significantly reduced | triglyceride-rich lipoprotein concentrations | Human | participants with BMI ranging from 27 to 34 kg/m2 | Not specified | Changes in triglyceride-rich lipoprotein particle profiles in response to one-week on a low fat or Mediterranean diet by TCF7L2 rs7903146 genotype: a randomized crossover dietary intervention trial. |
| Mediterranean-type diet (MetD) | Increases - benefit more from | triglyceride-rich lipoprotein profile | Human | rs7903146 TT carriers | Not specified | Changes in triglyceride-rich lipoprotein particle profiles in response to one-week on a low fat or Mediterranean diet by TCF7L2 rs7903146 genotype: a randomized crossover dietary intervention trial. |
| high-monounsaturated fatty acid (MUFA) diet | Decreases - lowered | VLDL triglyceride | Human | free-living individuals with Type 2 diabetes mellitus | MUFA diet (40% energy from fat, primarily virgin olive oil). | Comparison of a high-carbohydrate and a high-monounsaturated fat, olive oil-rich diet on the susceptibility of LDL to oxidative modification in subjects with Type 2 diabetes mellitus.cited 50× |
| cottonseed oil (CSO; PUFA rich) diet enrichment | Decreases - showing protection | postprandial triglyceride responses | Human | hypercholesterolemic adults | 30% of daily energy needs from either CSO or OO, provided via meals and snacks covering ~60% of daily energy requirements. | Blood Lipid Responses to Diets Enriched with Cottonseed Oil Compared With Olive Oil in Adults with High Cholesterol in a Randomized Trial.cited 13× |
| healthy diet with regional foods alongside 1 kg of P. ostreatus per week | Decreases - decreased | triglyceride levels | Human | women | 1 kg of Pleurotus ostreatus per week (four portions of 250 g). | Dietary Supplementation with Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), Reduces Visceral Fat and Hyperlipidemia in Inhabitants of a Rural Community in Mexico.cited 1× |
| healthy diet with regional foods alongside 1 kg of P. ostreatus per week | Decreases - decreased | triglyceride levels | Human | men | 1 kg of Pleurotus ostreatus per week (four portions of 250 g). | Dietary Supplementation with Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), Reduces Visceral Fat and Hyperlipidemia in Inhabitants of a Rural Community in Mexico.cited 1× |
| healthy diet with regional foods without the inclusion of edible mushrooms | Decreases - decreased | triglyceride levels | Human | women | 1 kg of Pleurotus ostreatus per week (four portions of 250 g). | Dietary Supplementation with Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), Reduces Visceral Fat and Hyperlipidemia in Inhabitants of a Rural Community in Mexico.cited 1× |
| high-lipid diet | Increases - significantly upregulated | hepatic triglyceride (TG) levels | Animal | zebrafish (Danio rerio) | Not specified | The Potential Role of Intestinal Microbiota on the Intestine-Protective and Lipid-Lowering Effects of Berberine in Zebrafish (Danio rerio) Under High-Lipid Stress. |
| high carbohydrate diet | Increases - an increase in | total cholesterol and triglyceride levels | Animal | male Wistar rats | Not specified | Whole tomato lipidic extract improved sperm quality in obese rats induced by a high-carbohydrate diet.cited 1× |
| 0.25% carnosine plus 0.25% AA in diet | Decreases - resulted in lower levels of | plasma triglyceride | HumanAnimalMolecular | diabetic mice | 0.5 μM carnosine plus 0.5 μM AA (in vitro); 0.25% carnosine plus 0.25% AA in diet (in vivo). | Combination of carnosine and asiatic acid provided greater anti-inflammatory protection for HUVE cells and diabetic mice than individual treatments of carnosine or asiatic acid alone.cited 6× |
| low-calorie (25% of energy deficit) nuts containing diet (NELCD) | Decreases - reduced significantly | triglyceride | Human | stable CAD patients who were overweight or obese | Not specified (nuts included as part of a 25% energy-deficit diet). | A calorie-restricted diet with nuts favourably raises plasma high-density lipoprotein-cholesterol in overweight and obese patients with stable coronary heart disease: A randomised controlled trial.cited 7× |
| nut-free energy-restricted diet (NFLCD) | Decreases - reduced significantly | triglyceride | Human | stable CAD patients who were overweight or obese | Not specified (nuts included as part of a 25% energy-deficit diet). | A calorie-restricted diet with nuts favourably raises plasma high-density lipoprotein-cholesterol in overweight and obese patients with stable coronary heart disease: A randomised controlled trial.cited 7× |
| low glycemic index diet (LGID) | Decreases - significantly decreased | triglyceride levels | Human | Turkish children with drug-resistant epilepsy (DRE) | Not specified | The effects of low glycemic index diet on epileptic seizure frequency, oxidative stress, mental health, and health-related quality of life in children with drug-resistant epilepsy. |
| HFHC diet | Increases - a marked increase in hepatic triglyceride levels | hepatic triglyceride levels | Animal | C57BL/6J mice | Not specified. | Dissociation of hepatic insulin resistance from susceptibility of nonalcoholic fatty liver disease induced by a high-fat and high-carbohydrate diet in mice.cited 31× |
| calorie-restriction diet with fish oil supplementation (CRF) | Decreases - decreased significantly | triglyceride (TG) levels | Human | female MetS patients | Not specified | A calorie-restriction diet supplemented with fish oil and high-protein powder is associated with reduced severity of metabolic syndrome in obese women.cited 27× |
| calorie-restriction meal-replacement diet with fish oil supplementation (CRMRF) | Decreases - decreased significantly | triglyceride (TG) levels | Human | female MetS patients | Not specified | A calorie-restriction diet supplemented with fish oil and high-protein powder is associated with reduced severity of metabolic syndrome in obese women.cited 27× |
| calorie-restriction meal-replacement diet (CRMR) | Decreases - decreased significantly | triglyceride (TG) levels | Human | female MetS patients | Not specified | A calorie-restriction diet supplemented with fish oil and high-protein powder is associated with reduced severity of metabolic syndrome in obese women.cited 27× |
| hypocaloric low glycemic index (LGI) diet | Decreases - changes were significantly lower | triglyceride concentrations | Human | obese outpatient children | Not specified (diets had glycemic indexes of 60 for LGI and 90 for HGI). | Metabolic changes after a hypocaloric, low-glycemic-index diet in obese children.cited 41× |
| flaxseed added to a weight loss diet | Decreases - decrease | triglyceride levels | Human | men with cardiovascular risk factors | 60g of flaxseed powder per day. | Impact of weight loss diet associated with flaxseed on inflammatory markers in men with cardiovascular risk factors: a clinical study.cited 43× |
| ketogenic diet (KD) | Decreases - decreases | triglyceride (TG) | Human | overweight or obese polycystic ovary syndrome (PCOS) patients | Not specified. | Impact of short-term ketogenic diet on sex hormones and glucose-lipid metabolism in overweight or obese patients with polycystic ovary syndrome.cited 1× |
| ketogenic diet (KD) | Decreases - significant reductions | triglyceride (TG) | Human | overweight or obese polycystic ovary syndrome (PCOS) patients | Not specified. | Impact of short-term ketogenic diet on sex hormones and glucose-lipid metabolism in overweight or obese patients with polycystic ovary syndrome.cited 1× |
| ketogenic diet | Decreases - significantly decreased | triglyceride | Human | patients with MASLD | Not specified | Effect of a Ketogenic Diet on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Progression: A Randomized Controlled Trial.cited 2× |
| orlistat therapy combined with a low-fat diet (O + LFD) | Decreases - improved similarly within both groups | triglyceride levels | Human | Overweight or obese outpatients from the Department of Veterans Affairs primary care clinics in Durham, North Carolina | Low-fat diet (<30% energy from fat, 500-1000 kcal/d deficit) combined with orlistat (120 mg orally 3 times daily). | A randomized trial of a low-carbohydrate diet vs orlistat plus a low-fat diet for weight loss.cited 110× |
| low-carbohydrate, ketogenic diet (LCKD) | Decreases - improved similarly within both groups | triglyceride levels | Human | Overweight or obese outpatients from the Department of Veterans Affairs primary care clinics in Durham, North Carolina | Low-fat diet (<30% energy from fat, 500-1000 kcal/d deficit) combined with orlistat (120 mg orally 3 times daily). | A randomized trial of a low-carbohydrate diet vs orlistat plus a low-fat diet for weight loss.cited 110× |
| buckwheat sprouts (BS) diet (5% or 10%) | Decreases - were lower than | hepatic triglyceride | Animal | type 2 diabetic mice (db/db) | — | Effects of buckwheat sprouts on plasma and hepatic parameters in type 2 diabetic db/db mice. |
| Gluten free diet (GFD) | Decreases - reduced | serum triglyceride concentration | Human | subjects diagnosed with MES | Not specified | The Effect of Gluten Free Diet on Components of Metabolic Syndrome: A Randomized Clinical Trial.cited 22× |
| Gluten free diet (GFD) | Increases - improved | Triglyceride level | Human | subjects with the metabolic syndrome | Not specified | The Effect of Gluten Free Diet on Components of Metabolic Syndrome: A Randomized Clinical Trial.cited 22× |
| low-fat diet | Decreases - significantly lower | serum triglyceride concentrations | Animal | Miniature Schnauzer with hypertriglyceridemia | Not specified (commercially available low-fat diet). | Effect of a low-fat diet on serum triglyceride and cholesterol concentrations and lipoprotein profiles in Miniature Schnauzers with hypertriglyceridemia.cited 14× |
| low-fat diet | Decreases - effective in reducing | serum triglyceride concentrations | Animal | Miniature Schnauzer with hypertriglyceridemia | Not specified (commercially available low-fat diet). | Effect of a low-fat diet on serum triglyceride and cholesterol concentrations and lipoprotein profiles in Miniature Schnauzers with hypertriglyceridemia.cited 14× |
| hypocaloric diet with a Mediterranean pattern enriched in ω-6 polyunsaturated fatty acids (PUFA) | Decreases - decreased | triglyceride levels | Human | non-C allele carriers | Not specified. | APOA-5 genetic variant and a hypocaloric diet enriched in ω-6 fatty acids with Mediterranean pattern. |
| hypocaloric diet with a Mediterranean pattern enriched in ω-6 polyunsaturated fatty acids (PUFA) | No effect - produces a worse response | triglyceride levels | Human | minor C allele of the APOA5 gene (rs662799) carriers | Not specified. | APOA-5 genetic variant and a hypocaloric diet enriched in ω-6 fatty acids with Mediterranean pattern. |
| low-fat, high carbohydrate (LFHC) diet | Decreases - decreased significantly | Total plasma triglyceride levels | Human | 10 patients affected by familial endogenous hypertriglyceridemia | Approximately 60% of energy as carbohydrate (isocaloric diet). | Long-term effect of a low-fat, high-carbohydrate diet on plasma lipids of patients affected by familial endogenous hypertriglyceridemia.cited 22× |
| low-fat, high-carbohydrate (CARB) diet | Increases - rises | triglyceride | Human | forty healthy subjects | Not specified (diet contained at least 25 g of relevant fat or was low-fat, high-carbohydrate) | Flow-mediated dilatation is impaired by a high-saturated fat diet but not by a high-carbohydrate diet.cited 121× |
| diet control alone | Decreases - appears to significantly reduce | total cholesterol and triglyceride levels | Human | — | Not specified | Assessing the independent effect of dietary counseling and hypolipidemic medications on serum lipids.cited 7× |
| vegan diet | No effect - no significant differences | fasting plasma triglyceride levels | Human | community-dwelling older adults | Not specified beyond dietary composition (60% animal protein in omnivorous diet). | A Well-Balanced Vegan Diet Does not Compromise Daily Mixed Muscle Protein Synthesis Rates when Compared with an Omnivorous Diet in Active Older Adults: A Randomized Controlled Cross-Over Trial.cited 2× |
| vegan diet | Decreases - reduce | triglyceride levels | Human | — | Not specified | The Effect of a Vegan Diet on the Health Indicators and Outcomes of Patients with Type 2 Diabetes Mellitus. |
| HPLC diet (high-protein low-carbohydrate: 45 % protein, 30 % carbohydrate) | Decreases - reduced | plasma triglyceride | Animal | Rats | 45% protein, 30% carbohydrate (HPLC diet); 20% protein, 56% carbohydrate (MPMC diet) | Metabolomic analysis reveals distinct profiles in the plasma and urine of rats fed a high-protein diet.cited 14× |
| feeding with high fat/high cholesterol (HF/HC) diet in HSLiKO mice | No effect - unaltered | triglyceride | Animal | HSLiKO mice | — | Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice. |
| low fat (15% kcal), high fiber, soy protein supplemented diet | Decreases - decreased | serum triglyceride levels | Human | men with prostate cancer | 15% kcal from fat, high fiber, soy protein supplemented diet. | Growth inhibitory effect of low fat diet on prostate cancer cells: results of a prospective, randomized dietary intervention trial in men with prostate cancer.cited 68× |
| Western-styled diet enriched in saturated fatty acids (SFA) | No effect - remained comparable to | blood glucose and triglyceride concentrations | Animal | wild-type C57BL/6J mice | Not explicitly stated, but chronic ingestion over 13 weeks. | Chronic Intake of Energy Drinks and Their Sugar Free Substitution Similarly Promotes Metabolic Syndrome.cited 6× |
| myo-inositol plus diet | Decreases - improved | triglyceride serum levels | Human | postmenopausal women affected by the metabolic syndrome | 2 g twice daily (BID). | Effects of myo-inositol supplementation in postmenopausal women with metabolic syndrome: a perspective, randomized, placebo-controlled study.cited 66× |
| including flaxseed in the HFHS diet | Decreases - reduced | hepatic cholesterol and triglyceride content | Animal | obese male and female rats | Not specified | Beneficial Effects of Dietary Flaxseed on Non-Alcoholic Fatty Liver Disease.cited 3× |
| diet rich in monounsaturated fatty acid (MUFA) | Decreases - were lower | triglyceride levels | Human | Men and women aged 35 to 69 years who were nonsmokers with no chronic illness and not on any medication | Fat intake constituted 20.3% of total energy in the MUFA diet (specific sunflower oil dosage not detailed). | A diet rich in high-oleic-acid sunflower oil favorably alters low-density lipoprotein cholesterol, triglycerides, and factor VII coagulant activity.cited 50× |
| a 2-week diet that increased the proportion of SFA (<40% to 60% of dietary fat) | Increases - increase | proportion of SFA in the intramyocellular triglyceride pool | Human | overweight young adults | Increased proportion of saturated fat from <40% to 60% of dietary fat, maintaining total fat, carbohydrate, protein, and calorie intake. | Changes in markers for cardio-metabolic disease risk after only 1-2 weeks of a high saturated fat diet in overweight adults.cited 5× |
| low-carbohydrate or low-fat diet with varenicline | Decreases - more favorable | triglyceride concentrations | Human | quitters | Not specified (dietary counseling focused on low-carbohydrate or low-fat diets). | Smoking cessation improves cardiometabolic risk in overweight and obese subjects treated with varenicline and dietary counseling.cited 9× |
| low-carbohydrate and high-fiber diet and education | Decreases - were lower | triglyceride | Human | female patients with nonalcoholic fatty liver disease | Not specified | Impact of a low-carbohydrate and high-fiber diet on nonalcoholic fatty liver disease.cited 12× |
| low-carbohydrate and high-fiber diet and education | Decreases - were lower | triglyceride | Human | male patients with nonalcoholic fatty liver disease | Not specified | Impact of a low-carbohydrate and high-fiber diet on nonalcoholic fatty liver disease.cited 12× |
| modified DASH diet | Decreases - can reduce | triglyceride concentration | Human | hypertension patients | Not specified | Effects of the Modified DASH Diet on Adults With Elevated Blood Pressure or Hypertension: A Systematic Review and Meta-Analysis.cited 29× |
| modified DASH diet | Decreases - could affect | triglyceride concentration | Human | hypertensive and pre-hypertensive adults | Not specified | Effects of the Modified DASH Diet on Adults With Elevated Blood Pressure or Hypertension: A Systematic Review and Meta-Analysis.cited 29× |
| normal diet (ND) combined with high-intensity interval training (HIIT) | No effect - improved | triglyceride (TG) | Human | overweight/obese adults | IER: 30% of energy needs on 2 non-consecutive days/week, 100% on other 5 days; CER: 70% of energy needs daily. | Differential effects of intermittent energy restriction vs. continuous energy restriction combined high-intensity interval training on overweight/obese adults: A randomized controlled trial.cited 4× |
| high-carbohydrate/low-fiber diet | Increases - induced a significant increase | fasting plasma triglyceride concentrations | Human | both groups | 60% energy from carbohydrate, 20% from fat (high-carbohydrate diet); 40% energy from carbohydrate, 40% from fat (low-carbohydrate diet). | Does a high-carbohydrate diet have different effects in NIDDM patients treated with diet alone or hypoglycemic drugs?cited 29× |
| Combined high-fructose, high-fat, high-cholesterol diet and ethanol administration (FFC-EtOH) | Increases - increased | hepatic triglyceride levels | Animal | Male C57BL6/J mice | High-fructose, high-fat, high-cholesterol diet (FFC) for 4 weeks, followed by 5% ethanol in drinking water plus weekly 2.5 g/kg ethanol gavage for 12 weeks | Concomitant western diet and chronic-binge alcohol dysregulate hepatic metabolism.cited 7× |
| MFGM diet (whipping cream) | No effect - did not differ | triglyceride | Human | overweight men and women | 40 g milk fat/day as either whipping cream or butter oil. | Potential role of milk fat globule membrane in modulating plasma lipoproteins, gene expression, and cholesterol metabolism in humans: a randomized study.cited 89× |
| DASH diet | Decreases - significant trends were observed | triglyceride | Human | adults from 27 counties of Khuzestan province, Iran | Not specified | The Association between DASH Diet Adherence and Cardiovascular Risk Factors.cited 8× |
| DASH diet | Decreases - significant reduction | triglyceride (TG) | Human | subjects with MetS | Not specified | The effect of dietary approaches to stop hypertension (DASH) diet on fatty liver and cardiovascular risk factors in subjects with metabolic syndrome: a randomized controlled trial.cited 6× |
| 28%P/46%C diet supplemented with 0.16% MCS | Decreases - decreased | contents of triglyceride | Animal | juvenile common carp (Cyprinus carpio) | 0.16% MCS supplementation in the 28%P/46%C diet. | Momordica charantia saponins administration in low-protein-high-carbohydrate diet improves growth, blood biochemical, intestinal health and microflora composition of juvenile common carp (Cyprinus carpio).cited 4× |
| diet supplemented with 1.14 g per day of docosahexaenoic acid (DHA) for eight weeks | Increases - increased | plasma DHA availability in non-esterified fatty acids (NEFAs) and triglyceride fatty acids (TGFAs) | Human | fifteen volunteer male football players | 1.14 g per day. | Effect of DHA on plasma fatty acid availability and oxidative stress during training season and football exercise.cited 26× |
| NuSun sunflower oil diet | No effect - no effect | triglyceride levels | Human | men and women with moderate hypercholesterolemia | Experimental diets provided 30% fat, with NuSun sunflower oil contributing half of the total fat (specific dosage not detailed). | Balance of unsaturated fatty acids is important to a cholesterol-lowering diet: comparison of mid-oleic sunflower oil and olive oil on cardiovascular disease risk factors.cited 33× |
| Prenatal ethanol exposure (PEE) with high-fat diet (HFD) | Increases - increased | serum IGF-1, glucose and triglyceride (TG) | Animal | female fetus and adult offspring | — | Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. |
| modified AHA (mAHA) Step I diet containing 3.4% soy lecithin | No effect - no significant effect on | plasma triglyceride (TG) | Animal | cynomolgus monkeys | 3.4% soy lecithin in diet. | Soy lecithin reduces plasma lipoprotein cholesterol and early atherogenesis in hypercholesterolemic monkeys and hamsters: beyond linoleate.cited 56× |
| Mediterranean diet alone (MeD) | Decreases - significantly decreased | triglyceride (TG) | Human | people with NAFLD | 250 mg of beetroot juice. | Comparing effects of beetroot juice and Mediterranean diet on liver enzymes and sonographic appearance in patients with non-alcoholic fatty liver disease: a randomized control trials.cited 1× |
| Mediterranean diet with beet juice (BJ + MeD) | Decreases - significantly decreased | triglyceride (TG) | Human | people with NAFLD | 250 mg of beetroot juice. | Comparing effects of beetroot juice and Mediterranean diet on liver enzymes and sonographic appearance in patients with non-alcoholic fatty liver disease: a randomized control trials.cited 1× |
| Mediterranean-like, culturally contextualized Asian diet rich in fiber and unsaturated fatty acids | Decreases - achieved significantly greater reductions in | triglyceride concentrations | Human | Chinese females with NAFLD | Not specified for fiber alone. | Effect of an Asian-adapted Mediterranean diet and pentadecanoic acid on fatty liver disease: the TANGO randomized controlled trial.cited 20× |
| control diet (CNT, no PP) | Increases - had the highest concentrations | triglyceride | Animal | Arabi male lambs | Not specified | Use of tannase-producing bacteria isolated from the rumen to improve the nutritional value of pomegranate peel for fattening lambs.cited 2× |
| fruit rich diet (FRD) with consumption of at least 4 servings of fruits daily | Increases - had significantly higher | triglyceride (TG) | Human | adults with NAFLD | At least 4 servings of fruits daily (FRD group) vs. less than 2 servings/day (control group). | The effect of a fruit-rich diet on liver biomarkers, insulin resistance, and lipid profile in patients with non-alcoholic fatty liver disease: a randomized clinical trial.cited 19× |
| hypocaloric diet with 1 Hass avocado daily | No effect - no change | serum triglyceride | Human | healthy overweight/obese women and men | 1 Hass avocado daily. | Hass Avocado Inclusion in a Weight-Loss Diet Supported Weight Loss and Altered Gut Microbiota: A 12-Week Randomized, Parallel-Controlled Trial.cited 35× |
| hypocaloric diet with 1 Hass avocado daily | Decreases - significant decrease from baseline to 12 wk | serum triglyceride | Human | healthy overweight/obese women and men | 1 Hass avocado daily. | Hass Avocado Inclusion in a Weight-Loss Diet Supported Weight Loss and Altered Gut Microbiota: A 12-Week Randomized, Parallel-Controlled Trial.cited 35× |
| cholesterol-enriched diet | No effect - did not change | serum triglyceride level | Animal | Male Wistar rats | Not specified | Effect of a multivitamin preparation supplemented with phytosterol on serum lipids and infarct size in rats fed with normal and high cholesterol diet.cited 16× |
| high-MUFA diet | Decreases - had more beneficial effects | plasma triglyceride concentrations | Human | sixty-three men | 58% of energy as carbohydrates (ad libitum consumption) | Variations in body composition and plasma lipids in response to a high-carbohydrate diet.cited 25× |
| low-calorie Mediterranean diet | Decreases - greater reduction | triglyceride levels | Human | overweight omnivores with a low-to-moderate cardiovascular risk profile | Not specified (low-calorie diets). | Low-Calorie Vegetarian Versus Mediterranean Diets for Reducing Body Weight and Improving Cardiovascular Risk Profile: CARDIVEG Study (Cardiovascular Prevention With Vegetarian Diet).cited 132× |
| unfermented high fat diet | Increases - characterized | cholesterogenesis, triglyceride constipation and phospholipidosis in extra-hepatic tissues | Animal | rats | — | Hypolipidemic effects of lactic acid bacteria fermented cereal in rats. |
| a switch to a very low carbohydrate (30% of total calorie) diet | Decreases - came down | triglyceride level | Human | 17-year-old girl with recurrent attacks of acute pancreatitis, severe hyperglycemia and hypertriglyceridemia | 30% of total daily calorie intake from carbohydrates (reduced from 70%). | A very low carbohydrate diet improved metabolic profile in congenital generalized lipodystrophy type 4.cited 1× |
| low-carbohydrate diet | Decreases - favourable changes | levels of triglyceride | Human | patients with type 2 diabetes | Not Assessed | The use of low-carbohydrate diet in type 2 diabetes - benefits and risks.cited 14× |
| low-carbohydrate diet (LCD) | Decreases - were significantly lower than that of the LFD | Triglyceride (TG) | Human | adolescents with overweight and obesity | Not specified | Low-Carbohydrate Diet is More Helpful for Weight Loss Than Low-Fat Diet in Adolescents with Overweight and Obesity: A Systematic Review and Meta-Analysis.cited 2× |
| low-carbohydrate diet | Decreases - greater decreases in triglyceride level | triglyceride level | Human | 148 men and women without clinical cardiovascular disease and diabetes | Low-carbohydrate (<40 g/d) or low-fat (<30% of daily energy intake from total fat, <7% saturated fat). | Effects of low-carbohydrate and low-fat diets: a randomized trial.cited 208× |
| low-carbohydrate diet | Decreases - improvements | triglyceride levels | Human | Japanese patients with type 2 diabetes unable to adhere to a calorie-restricted diet | Not specified | A non-calorie-restricted low-carbohydrate diet is effective as an alternative therapy for patients with type 2 diabetes.cited 90× |
| low-carbohydrate diet | Decreases - had greater reductions | triglyceride levels | Human | 307 participants with a mean age of 45.5 years and mean body mass index of 36.1 kg/m(2) | 1200 to 1800 kcal/day, ≤30% calories from fat. | Weight and metabolic outcomes after 2 years on a low-carbohydrate versus low-fat diet: a randomized trial.cited 372× |
| combination of exercise training and fiber-rich diet | Decreases - decreased | plasma triglyceride levels | Animal | Male APOE*3-Leiden.CETP mice | 10% inulin (fiber) in the diet. | Combination of dietary fiber and exercise training improves fat loss in mice but does not ameliorate MASLD more than exercise alone. |
| high cholesterol diet (HCD) | Increases - exhibited | serum total cholesterol (TC) and triglyceride (TG) levels | AnimalMolecular | zebrafish | Final concentration of 0.1 mg/ml in vitro; dosage in vivo not specified. | Grape skin and loquat leaf extracts and acai puree have potent anti-atherosclerotic and anti-diabetic activity in vitro and in vivo in hypercholesterolemic zebrafish.cited 30× |
| high-cholesterol diet | Increases - showed elevated | serum triglyceride levels | Molecular | hamsters | — | In vivo biochemical and gene expression analyses of the antioxidant activities and hypocholesterolaemic properties of Tamarindus indica fruit pulp extract. |