36
14
11
↑36
↓14
—11
Evidence suggests Ketogenic Diet mayincreaseSurvival.
37 studies (61 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| regular chow diet with no other treatment | Decreases - only one of 11 rats survived | survival | Animal | spontaneously hypertensive rats | — | Telmisartan improves survival and ventricular function in SHR rats with extensive cardiovascular damage induced by dietary salt excess. |
| regular diet plus telmisartan | Increases - only one of nine rats died; eight survived 30 days | survival | Animal | spontaneously hypertensive rats | — | Telmisartan improves survival and ventricular function in SHR rats with extensive cardiovascular damage induced by dietary salt excess. |
| unhealthful plant-based diet index (uPDI) | No effect - was not associated with worse survival | overall survival (OS) | Human | patients with metastatic CRC | Not specified (dietary indices based on food frequency questionnaires). | Plant-based diet and survival among patients with metastatic colorectal cancer.cited 1× |
| unhealthful plant-based diet index (uPDI) | No effect - was not associated with worse survival | progression-free survival (PFS) | Human | patients with metastatic CRC | Not specified (dietary indices based on food frequency questionnaires). | Plant-based diet and survival among patients with metastatic colorectal cancer.cited 1× |
| plant-based diet index (PDI) | Decreases - had significantly better survival | overall survival (OS) | Human | patients with metastatic CRC | Not specified (dietary indices based on food frequency questionnaires). | Plant-based diet and survival among patients with metastatic colorectal cancer.cited 1× |
| plant-based diet index (PDI) | Decreases - had significantly better survival | progression-free survival (PFS) | Human | patients with metastatic CRC | Not specified (dietary indices based on food frequency questionnaires). | Plant-based diet and survival among patients with metastatic colorectal cancer.cited 1× |
| healthful plant-based diet index (hPDI) | Decreases - Similar findings were observed | overall survival (OS) | Human | patients with metastatic CRC | Not specified (dietary indices based on food frequency questionnaires). | Plant-based diet and survival among patients with metastatic colorectal cancer.cited 1× |
| healthful plant-based diet index (hPDI) | Decreases - Similar findings were observed | progression-free survival (PFS) | Human | patients with metastatic CRC | Not specified (dietary indices based on food frequency questionnaires). | Plant-based diet and survival among patients with metastatic colorectal cancer.cited 1× |
| MCT diet | Increases - survival was improved | survival | Animal | litters from sows fed MCT | 10% MCT in the diet (isoenergetic and isonitrogenous with control and LCT diets). | Effects of adding medium-chain triglycerides to sow diets during late gestation and early lactation on litter performance.cited 31× |
| MCT diet | No effect - survival | survival | Animal | pigs weighing < 900 g at birth in MCT treatment | 10% MCT in the diet (isoenergetic and isonitrogenous with control and LCT diets). | Effects of adding medium-chain triglycerides to sow diets during late gestation and early lactation on litter performance.cited 31× |
| MCT diet | No effect - survival rates | survival rates | Animal | MCT group | 10% MCT in the diet (isoenergetic and isonitrogenous with control and LCT diets). | Effects of adding medium-chain triglycerides to sow diets during late gestation and early lactation on litter performance.cited 31× |
| LCT diet | No effect - survival | survival | Animal | pigs weighing < 900 g at birth in LCT treatment | 10% MCT in the diet (isoenergetic and isonitrogenous with control and LCT diets). | Effects of adding medium-chain triglycerides to sow diets during late gestation and early lactation on litter performance.cited 31× |
| LCT diet | No effect - survival rates | survival rates | Animal | LCT group | 10% MCT in the diet (isoenergetic and isonitrogenous with control and LCT diets). | Effects of adding medium-chain triglycerides to sow diets during late gestation and early lactation on litter performance.cited 31× |
| control diet | No effect - survival | survival | Animal | pigs weighing < 900 g at birth in control treatment | 10% MCT in the diet (isoenergetic and isonitrogenous with control and LCT diets). | Effects of adding medium-chain triglycerides to sow diets during late gestation and early lactation on litter performance.cited 31× |
| control diet | No effect - survival rates | survival rates | Animal | control group | 10% MCT in the diet (isoenergetic and isonitrogenous with control and LCT diets). | Effects of adding medium-chain triglycerides to sow diets during late gestation and early lactation on litter performance.cited 31× |
| 30% protein diet | Decreases - modest but significant decrease | survival with heart failure | Animal | rats with aortic constriction | 30% of energy intake from protein (high-protein diet) vs. 18% (standard diet). | Effect of a high-protein diet on development of heart failure in response to pressure overload.cited 12× |
| high-protein diet | Decreases - significantly decreased | survival | Animal | rats with pressure overload induced heart failure | 30% of energy intake from protein (high-protein diet) vs. 18% (standard diet). | Effect of a high-protein diet on development of heart failure in response to pressure overload.cited 12× |
| diet changed from one chow with a high essential fatty acid (EFA) ratio (n-6/n-3, 14.5) to another with a low n-6/n-3 ratio (3.0) within 6 days after the onset of overt diabetes | Increases - survived significantly longer | survival | Animal | NOD mice, a type 1 diabetes model | Not specified (dietary ratio change from n-6/n-3 14.5 to 3.0). | Diet with a low n-6/n-3 essential fatty acid ratio when started immediately after the onset of overt diabetes prolongs survival of type 1 diabetes model NOD mice.cited 14× |
| switching obese mice to low-fat diet prior to vincristine | Increases - led to dramatically improved survival | survival from ALL | HumanAnimalMolecular | obese mice | Not specified (diet composition: 10% low-fat diet vs. 60% high-fat diet). | Switch to low-fat diet improves outcome of acute lymphoblastic leukemia in obese mice.cited 18× |
| diet-induced obesity (60% calories from fat diet) | Decreases - had poorer survival | survival from ALL after vincristine monotherapy | HumanAnimalMolecular | DIO mice | Not specified (diet composition: 10% low-fat diet vs. 60% high-fat diet). | Switch to low-fat diet improves outcome of acute lymphoblastic leukemia in obese mice.cited 18× |
| control diet (10% low fat diet) | Increases - had better survival | survival from ALL after vincristine monotherapy | HumanAnimalMolecular | control mice | Not specified (diet composition: 10% low-fat diet vs. 60% high-fat diet). | Switch to low-fat diet improves outcome of acute lymphoblastic leukemia in obese mice.cited 18× |
| high-fat diet | Increases - in conjunction with better control of malabsorption due to microspheric pancreatic enzyme replacement therapy, attention to adequate fat-soluble vitamin supplementation and newborn screening has ensured | better health and survival through their adult years | Human | children with CF | Not specified | Nutritional care in children with cystic fibrosis: are our patients becoming better?cited 37× |
| high-fat (HF) diet | No effect - neither PS nor HF affected | pup survival | Animal | female ICR mice | Not specified (dietary fat content: 10% for control, 60% for high-fat). | Exposure to circadian disrupting environment and high-fat diet during pregnancy and lactation alter reproductive competence and lipid profiles of liver, mammary, plasma and milk of ICR mice. |
| High-fat diet (HFD) | Decreases - had a negative effect on | survival | Animal | male mice | Not specified | Effects of a high-fat diet on cognition and brain distribution of intranasal insulin in E3 and E4 male and female mice.cited 1× |
| high-fat diet (HFD) | Decreases - was significantly lower | survival rate | Animal | Male C57/Bl6 mice with stroke | 100 mg/kg, administered orally. | Silymarin administration after cerebral ischemia improves survival of obese mice by increasing cortical BDNF and IGF1 levels. |
| low-sodium diet | Increases - may be associated with improved | survival and kidney function | Human | kidney transplant recipients (KTRs) | Not specified | Current Evidence on Dietary Factors and Kidney Allograft Function in Kidney Transplant Recipients: A Systematic Review.cited 1× |
| moderate protein diet | Increases - may be associated with improved | survival and kidney function | Human | kidney transplant recipients (KTRs) | Not specified | Current Evidence on Dietary Factors and Kidney Allograft Function in Kidney Transplant Recipients: A Systematic Review.cited 1× |
| DASH diet | Increases - may be associated with improved | survival and kidney function | Human | kidney transplant recipients (KTRs) | Not specified | Current Evidence on Dietary Factors and Kidney Allograft Function in Kidney Transplant Recipients: A Systematic Review.cited 1× |
| Mediterranean diet | Increases - may be associated with improved | survival and kidney function | Human | kidney transplant recipients (KTRs) | Not specified | Current Evidence on Dietary Factors and Kidney Allograft Function in Kidney Transplant Recipients: A Systematic Review.cited 1× |
| alcohol abstinence and recommendation of nutritional supplements with high calorie, protein diet and vitamin E, C, thiamine | Decreases - plays a prime role in preventing disease progression and survival benefits | disease progression and survival | Human | pre and post-transplant cases | Not specified | A prognostic evaluation and management of alcoholic hepatitis.cited 10× |
| KGM-supplemented diet | Increases - significantly increased | the survival rate (%) of Caco-2 cells co-incubated with faecal water for 1 and 3 h | HumanAnimal | — | 4.5 g/d | Ameliorative effects of konjac glucomannan on human faecal β-glucuronidase activity, secondary bile acid levels and faecal water toxicity towards Caco-2 cells.cited 27× |
| AlCl3-diet | Decreases - significantly reduced | percentage survival | Animal | Drosophila melanogaster | Not specified | Sweet basil (Ocimum basilicum) leaf and seed extracts alleviate neuronal dysfunction in aluminum chloride-induced neurotoxicity in Drosophila melanogaster Meigen model. |
| high-carbohydrate diet (HC) | Increases - leads to a significant extension of | median and maximum survival times | Animal | Wistar rats | Not specified (ad libitum feeding). | Longevity extension in rats via improved redox homeostasis with high carbohydrate diet intervention from weaning to adulthood: a comprehensive multi-omics study. |
| high-carbohydrate diet (HCD, 60% dextrose) | Decreases - shorter survival | survival | Animal | homozygous knock-in (Bcs1lc.232A>G) mice (model of GRACILE syndrome) | 60% dextrose diet. | Effect of High-Carbohydrate Diet on Plasma Metabolome in Mice with Mitochondrial Respiratory Chain Complex III Deficiency.cited 10× |
| diet | Increases - can be statistically longer | disease-free intervals and survival times | Animal | dogs with Stage III lymphoma | — | Veterinary clinical nutrition: success stories: an overview. |
| curcumin-enriched diet | Increases - associated with improved | survival rates | Human | adults with colorectal cancer | Not specified. | The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic Review. |
| Yinchenhao Decoction (YD) supplementation at 4% in a high carbohydrate diet (HCD) | Increases - recorded the highest | survival rate after Nocardia seriolae challenge | Animal | juvenile largemouth bass | 0.5%, 1%, 2%, or 4% YD supplementation in HCD | Yinchenhao Decoction ameliorates the high-carbohydrate diet induced suppression of immune response in largemouth bass (Micropterus salmoides).cited 16× |
| low-protein diet (LPD) prescribed a LPD <0.6 g/kg ideal bodyweight | No effect - results were similar | survival and nutritional status | Human | patients | ≤0.8 g/kg ideal bodyweight and <0.6 g/kg ideal bodyweight. | The safety of a low-protein diet in older adults with advanced chronic kidney disease.cited 4× |
| low-protein diet (LPD) treatment | No effect - no difference in survival | survival | Human | older adults with advanced CKD | ≤0.8 g/kg ideal bodyweight and <0.6 g/kg ideal bodyweight. | The safety of a low-protein diet in older adults with advanced chronic kidney disease.cited 4× |
| High protein diet (HDP) | Increases - showed higher overall survival | overall survival | Human | older adults outpatients with advanced gastrointestinal cancer | HPD defined as ≥1.5 g/kg/day, with an average intake of 2.2 ± 0.8 g/kg/day. | High protein diet improves the overall survival in older adults with advanced gastrointestinal cancer.cited 14× |
| St. John's wort (SJW) extract-supplemented diet | Increases - significantly improve | overall survival | Animal | azoxymethane-treated mice | Not specified in the abstract. | St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling.cited 9× |
| ketogenic diet | Increases - had the highest median OS | median overall survival | Human | newly diagnosed cases | 1 g penicillamine (frequency not specified) | Role of nutritional adjuncts in the management of gliomas: A systematic review of literature.cited 2× |
| low copper diet coupled with 1 g penicillamine | Increases - had the highest median OS | median overall survival | Human | recurrent cases | 1 g penicillamine (frequency not specified) | Role of nutritional adjuncts in the management of gliomas: A systematic review of literature.cited 2× |
| ketogenic diet (KD) | Increases - reported a median overall survival | overall survival | Human | children with brain tumors | Classic KD with medium-chain triglyceride oil, modified Atkin, or low-carbohydrate diet (specific amounts not detailed). | Safety, Feasibility, and Effectiveness of Ketogenic Diet in Pediatric Patients With Brain Tumors: A Systematic Review. |
| ketogenic diet | Increases - increased overall survival | overall survival | Human | patients with glioma | Not available | Complementary and Alternative Medicine for the Treatment of Gliomas: Scoping Review of Clinical Studies, Patient Outcomes, and Toxicity Profiles.cited 2× |
| ketogenic diet | Increases - increased progression-free survival | progression-free survival | Human | patients with glioma | Not available | Complementary and Alternative Medicine for the Treatment of Gliomas: Scoping Review of Clinical Studies, Patient Outcomes, and Toxicity Profiles.cited 2× |
| ketogenic diet (KD) | Increases - prolong | patient survival | Human | patients with CRC | Not specified | Let food be thy medicine: the role of diet in colorectal cancer: a narrative review.cited 10× |
| Mediterranean diet (MD) | Increases - prolong | patient survival | Human | patients with CRC | Not specified | Let food be thy medicine: the role of diet in colorectal cancer: a narrative review.cited 10× |
| Dietary Approaches to Stop Hypertension (DASH) diet | Increases - prolong | patient survival | Human | patients with CRC | Not specified | Let food be thy medicine: the role of diet in colorectal cancer: a narrative review.cited 10× |
| diet and other lifestyle habits | Increases - increase | survival | Human | — | Not specified | Integrative Oncology Approaches to Reduce Recurrence of Disease and Improve Survival.cited 4× |
| feeding common carp with a diet containing 1 g/kg OLE over a period of 60 days | Increases - improve | survival rate against E. tarda | Animal | common carp | 0.0%, 0.1%, 0.25%, 0.50%, and 1.0% OLE in diet. | Dietary supplementation of olive leaf extract increases haematological, serum biochemical parameters and immune related genes expression level in common carp (Cyprinus carpio) juveniles.cited 20× |
| reducing systemic glucose by combining a ketogenic diet and metformin | Increases - increases overall survival | overall survival | Animal | — | Not specified (ketogenic diet composition and metformin dosage not detailed in abstract). | The combined treatment with ketogenic diet and metformin slows tumor growth in two mouse models of triple negative breast cancer.cited 3× |
| ketoanalogue-supplemented very low-protein diet (sVLPD) | Increases - increased | survival | Human | patients with CKD stage 4-5 | sVLPD (0.3-0.4 g/kg-day, vegetarian diet) supplemented with ketoanalogues (1 tablet/5 kg-day); LPD (0.6 g/kg-day, mixed proteins). | Economic Analysis of a Ketoanalogue-Supplemented Very Low-Protein Diet in Patients With Chronic Kidney Disease in Taiwan and Thailand.cited 6× |
| the ketogenic diet | Decreases - depriving them of the energy needed for | progression and survival | Human | cancer cells | Not specified. | The Ketogenic Diet in Colorectal Cancer: A Means to an End.cited 11× |
| Low-carbohydrate diet (LCD) associated with intranasal perillyl alcohol (POH) | Increases - may represent a viable option as adjunctive therapy for rGB to improve survival | overall survival | Human | recurrent GB (rGB) patients | Not specified. | Adjuvant effect of low-carbohydrate diet on outcomes of patients with recurrent glioblastoma under intranasal perillyl alcohol therapy.cited 4× |
| Mediterranean diet | Increases - promoted equivalent increases in | event-free survival | Human | secondary coronary prevention patients | Not specified (red wine included as part of the Mediterranean Diet). | Effects of high adherence to mediterranean or low-fat diets in medicated secondary prevention patients.cited 53× |
| low-fat Therapeutic Lifestyle Changes Diet | Increases - promoted equivalent increases in | event-free survival | Human | secondary coronary prevention patients | Not specified (red wine included as part of the Mediterranean Diet). | Effects of high adherence to mediterranean or low-fat diets in medicated secondary prevention patients.cited 53× |
| A nutrient-rich maternal diet before and during pregnancy | Increases - is associated with improved | fetal health, more appropriate birth weight, and increased rates of maternal and infant survival | Human | human subjects | Not specified | Current Concepts of Maternal Nutrition.cited 81× |