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Evidence suggests Resistance Training mayincreaseFatigue.
15 studies (22 claims)
Conflicting evidence
Typical effective dose 28500 (24250–32750) mgacross 2 dosed studies
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| home progressive resistance training (PRT) program augmented by neuromuscular electrical stimulation (NMES) | Decreases - improved significantly in impact of fatigue | impact of fatigue | Human | People with multiple sclerosis (MS) who use a walking aid | Not specified | Pilot randomized trial of progressive resistance exercise augmented by neuromuscular electrical stimulation for people with multiple sclerosis who use walking aids.cited 23× |
| high-intensity resistance training | Increases - improvements | muscle endurance to fatigue | Human | people with multiple sclerosis (PwMS) with predominantly unilateral hyposthenia of the ankle dorsiflexors | 6-week isokinetic training of the more affected ankle dorsiflexion muscles (specific intensity/frequency not detailed). | Time course of strength adaptations following high-intensity resistance training in individuals with multiple sclerosis.cited 11× |
| concurrent creatine supplementation and resistance training | Increases - enhance | fatigue resistance | Human | older adults | 20 g/day for 5 days or 2 g/day for 30 days | Use of creatine in the elderly and evidence for effects on cognitive function in young and old.cited 68× |
| Circuit resistance training (CRT) | Increases - effectively increased | muscular strength, aerobic capacity, and anaerobic fatigue resistance | Human | persons with chronic tetraplegia | 36-37g whey protein split before and after exercise (immediate PS) or 24h postexercise (delayed PS) | Circuit training and protein supplementation in persons with chronic tetraplegia.cited 16× |
| fast-velocity concentric resistance training (FVCRT) program | Decreases - improved in EG | symptomatic fatigue | Human | people with multiple sclerosis (MS) | Not specified | Effects of fast-velocity concentric resistance training in people with multiple sclerosis: A randomized controlled trial.cited 11× |
| progressive resistance training (PRT) | Decreases - reduced | fatigue impact | Human | people with multiple sclerosis (PwMS) with impaired mobility | Not specified | How do resistance training and balance and motor control training affect gait performance and fatigue impact in people with multiple sclerosis? A randomized controlled multi-center study.cited 40× |
| Combined resistance training with aerobic exercise | Increases - showed improvements in | cancer-related fatigue | Human | — | Not specified | The Effect of Nutrition Therapy and Exercise on Cancer-Related Fatigue and Quality of Life in Men with Prostate Cancer: A Systematic Review.cited 79× |
| Prescribing healthy eating guidelines with combined resistance training and aerobic exercise | Increases - improved | cancer-related fatigue | Human | — | Not specified | The Effect of Nutrition Therapy and Exercise on Cancer-Related Fatigue and Quality of Life in Men with Prostate Cancer: A Systematic Review.cited 79× |
| Resistance training | Increases - appears to be more effective in improving | cancer-related fatigue | Human | — | Not specified | The Effect of Nutrition Therapy and Exercise on Cancer-Related Fatigue and Quality of Life in Men with Prostate Cancer: A Systematic Review.cited 79× |
| Supervised moderate-hard resistance training with or without moderate-vigorous aerobic exercise | Increases - appears to improve | cancer-related fatigue | Human | — | Not specified | The Effect of Nutrition Therapy and Exercise on Cancer-Related Fatigue and Quality of Life in Men with Prostate Cancer: A Systematic Review.cited 79× |
| testosterone supplementation combined with progressive resistance training | Decreases - alleviate | fatigue | Human | males aged ≥70 suffering from mobility issues and testosterone insufficiency | Not specified | Testosterone and resistance training improved physical performance and reduced fatigue in frail older men: 1 year follow-up of a randomized clinical trial.cited 1× |
| adaptive variable-resistance training (Adaptive-VRT) | Decreases - reported lower | fatigue levels | Human | pediatric survivors of acute lymphoblastic leukemia (ALL) | Not specified (intervention involved Adaptive-VRT but exact dosage/frequency not detailed). | Effect of adaptive variable-resistance training on chemotherapy-induced sarcopenia, fatigue, and functional restriction in pediatric survivors of acute lymphoblastic leukemia: a prospective randomized controlled trial. |
| Heart failure Exercise And Resistance Training (HEART) Camp | Increases - significantly improved | dyspnea-fatigue index | Human | Participants with HFpEF | ≥120 minutes of moderate-intensity exercise per week (40%-80% of heart rate reserve). | The HEART Camp Exercise Intervention Improves Exercise Adherence, Physical Function, and Patient-Reported Outcomes in Adults With Preserved Ejection Fraction Heart Failure.cited 14× |
| endurance-based resistance training (ERT) program | Increases - positively affected | fatigue patterns during muscular endurance testing | Human | 27 participants (60-82 years of age) | 3.2 g/day | Beta-Alanine Does Not Enhance the Effects of Resistance Training in Older Adults.cited 3× |
| 8-week home-based physical activity intervention comprising twice weekly supervised resistance training and an unsupervized walking program | Increases - trends in favor of the exercise group over the control group were observed | Functional Assessment of Chronic Illness Therapy-Fatigue score | Human | women with metastatic breast cancer | Unsupervised walking program (frequency not specified) | Physical Activity for Symptom Management in Women With Metastatic Breast Cancer: A Randomized Feasibility Trial on Physical Activity and Breast Metastases.cited 45× |
| functional resistance training (FRT) during walking configured to resist the hip and knee | No effect - did not result in significant differences | peripheral fatigue | Molecular | non-disabled individuals | Not specified. | Functional resistance training during walking: do biomechanical and neural effects differ based on targeted joints?cited 1× |
| functional resistance training (FRT) during walking configured to resist the knee | No effect - did not result in significant differences | peripheral fatigue | Molecular | non-disabled individuals | Not specified. | Functional resistance training during walking: do biomechanical and neural effects differ based on targeted joints?cited 1× |
| resistance training (RES) | Decreases - attenuated increases in | cancer-treatment-related fatigue (CTRF) | Human | PCa patients undergoing RT | HIIT consisted of 8–15 × 60-second intervals (≥85% maximal heart rate), performed three times per week. | Effects of high-intensity interval training compared with resistance training in prostate cancer patients undergoing radiotherapy: a randomized controlled trial.cited 34× |
| resistance training | No effect - evidence is very uncertain about the effect compared with no training | long-term cancer-related fatigue (CRF) | Human | people with cancer during anticancer therapy | Not specified (structured, at least five sessions with face-to-face instruction). | Resistance training for fatigue in people with cancer. |
| resistance training | No effect - evidence is very uncertain about the effect compared with no training | medium-term cancer-related fatigue (CRF) | Human | people with cancer during anticancer therapy | Not specified (structured, at least five sessions with face-to-face instruction). | Resistance training for fatigue in people with cancer. |
| resistance training | Decreases - probably has a beneficial effect compared with no training | short-term cancer-related fatigue (CRF) | Human | people with cancer during anticancer therapy | Not specified (structured, at least five sessions with face-to-face instruction). | Resistance training for fatigue in people with cancer. |
| resistance training | No effect - evidence is very uncertain about the effect compared with no training | short-term cancer-related fatigue (CRF) | Human | people with cancer after anticancer therapy | Not specified (structured, at least five sessions with face-to-face instruction). | Resistance training for fatigue in people with cancer. |