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Effects of fast-velocity concentric resistance training in people with multiple sclerosis: A randomized controlled trial.

Acta neurologica Scandinavica
November 1, 2022
Luis Andreu-Caravaca et al. (6 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to analyze the effects of fast-velocity concentric resistance training (FVCRT) on strength, gait speed, walking endurance, fatigue, physical self-perception, and pain catastrophizing in people with multiple sclerosis (MS).

Results Summary

The study found that FVCRT significantly improved maximum strength in upper and lower limbs, gait speed, walking endurance, symptomatic fatigue, and pain catastrophizing in MS participants. The experimental group showed statistically significant improvements compared to the control group.

Population

People with multiple sclerosis (MS)

Effective Dosage

Not specified

Duration

10 weeks

Interactions

None mentioned

Extracted Claims (16)
InterventionDirectionEndpointPopulationDosageImpactClaim #
fast-velocity concentric resistance training (FVCRT) program
increase
maximum isometric voluntary contraction (MVIC) during knee extension on the right side
people with multiple sclerosis (MS)
p = .032; ES = -0.7
found inter-group differences after intervention
#1
fast-velocity concentric resistance training (FVCRT) program
increase
maximum isometric voluntary contraction (MVIC) during knee extension on the left side
people with multiple sclerosis (MS)
p = .009; ES = -0.9
found inter-group differences after intervention
#2
fast-velocity concentric resistance training (FVCRT) program
increase
hand-grip strength on the right side
people with multiple sclerosis (MS)
p = .003; ES = -1.0
found inter-group differences after intervention
#3
fast-velocity concentric resistance training (FVCRT) program
increase
hand-grip strength on the left side
people with multiple sclerosis (MS)
p = .029; ES = -0.7
found inter-group differences after intervention
#4
fast-velocity concentric resistance training (FVCRT) program
increase
maximum isometric voluntary contraction (MVIC) during knee extension on the right side
people with multiple sclerosis (MS)
p < .001; ES = -1.7
there was an increase after FVCRT
#5
fast-velocity concentric resistance training (FVCRT) program
increase
maximum isometric voluntary contraction (MVIC) during knee extension on the left side
people with multiple sclerosis (MS)
p < .001; ES = -1.3
there was an increase after FVCRT
#6
fast-velocity concentric resistance training (FVCRT) program
increase
hand grip strength on the right side
people with multiple sclerosis (MS)
p < .001; ES = -1.3
there was an increase after FVCRT
#7
fast-velocity concentric resistance training (FVCRT) program
increase
hand grip strength on the left side
people with multiple sclerosis (MS)
p < .001; ES = -1.3
there was an increase after FVCRT
#8
fast-velocity concentric resistance training (FVCRT) program
increase
gait speed
people with multiple sclerosis (MS)
p = .023; ES = 1.3
improved in EG
#9
fast-velocity concentric resistance training (FVCRT) program
increase
walking endurance
people with multiple sclerosis (MS)
p < .001; ES = -1.0
improved in EG
#10
fast-velocity concentric resistance training (FVCRT) program
decrease
symptomatic fatigue
people with multiple sclerosis (MS)
p = .004; ES = 0.6
improved in EG
#11
fast-velocity concentric resistance training (FVCRT) program
decrease
catastrophizing pain
people with multiple sclerosis (MS)
p < .001; ES = 1.0
improved in EG
#12
lower limb FVCRT
increase
upper and lower limb strength
MS participants
-
improved
#13
lower limb FVCRT
increase
walking
MS participants
-
improved
#14
lower limb FVCRT
decrease
symptomatic fatigue
MS participants
-
improved
#15
lower limb FVCRT
decrease
catastrophizing pain
MS participants
-
improved
#16
Abstract

OBJECTIVES: To analyze the effects of a fast-velocity concentric resistance training (FVCRT) program on maximum strength of upper and lower limb, gait speed, walking endurance, fatigue, physical self-perception, and catastrophizing pain in people with multiple sclerosis (MS). MATERIALS AND METHODS: Participants were randomized to either an experimental [EG] (n = 18) or a control [CG] (n = 12) group. The EG carried out 10-weeks of lower limb FVCRT. The CG did not perform any intervention. The maximum isometric voluntary contraction (MVIC) during knee extension, hand-grip strength, gait speed, walking endurance, fatigue, physical self-perception, and catastrophizing pain were measured. RESULTS: Inter-group differences after intervention were found on the right and left sides in MVIC (p = .032; ES = -0.7 and p = .009; ES = -0.9), and hand grip strength (p = .003; ES = -1.0 and p = .029; ES = -0.7). After FVCRT, there was in increase in MVIC (p < .001; ES = -1.7 and p < .001; ES = -1.3) and hand grip strength (p < .001; ES = -1.3 and p < .001; ES = -1.3) on both right and left sides, respectively. In addition, gait speed (p = .023; ES = 1.3), walking endurance (p < .001; ES = -1.0), symptomatic fatigue (p = .004; ES = 0.6), and catastrophizing pain (p < .001; ES = 1.0) improved in EG. CONCLUSION: Lower limb FVCRT improved the upper and lower limb strength, walking, symptomatic fatigue, and catastrophizing pain in MS participants.

Medical Subject Headings (MeSH)
FatigueHand StrengthHumansMultiple SclerosisMuscle StrengthPainResistance Training
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations11
Citations/Year3.7
Relative Citation Ratio2.21
NIH Percentile77.4%
Research Impact Scores
APT Score0.75
Weight Score2.66
Normalized Score0.70
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