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Evidence suggests Magnesium mayincreaseSleep depth.
14 studies (22 claims)
Emerging evidence
Typical effective dose 500 (500–500) mgacross 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| a formulation containing cannabidiol (CBD; 35 mg), cannabigerol (CBG; 50 mg), beta caryophyllene (BCP; 25 mg), branched-chain amino acids (BCAAs; 3.8 g), and magnesium citrate (420 mg) | No effect - There was no significant effect | sleep quality | Human | exercise-trained individuals | 35 mg CBD (combined with CBG, BCP, BCAAs, and magnesium citrate) | A randomized, double-blind, placebo-controlled, repeated-dose pilot study of the safety, tolerability, and preliminary effects of a cannabidiol (CBD)- and cannabigerol (CBG)-based beverage powder to support recovery from delayed onset muscle soreness (DOMS).cited 9× |
| magnesium and vitamin B6 supplements | Increases - improve | sleep quality | Human | RLS/WED patients | 40 mg daily | Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.cited 11× |
| magnesium and vitamin B6 | No effect - did not differ statistically | sleep quality and disease severity | Human | individuals with this illness for at least three months | 40 mg daily | Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.cited 11× |
| magnesium and vitamin B6 | Decreases - were significantly different | sleep quality and disease severity | Human | individuals with this illness for at least three months | 40 mg daily | Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.cited 11× |
| CoQ10, tryptophan, and magnesium supplementation | Decreases - showed a significant reduction | sleep quality | Human | patients with FM | Not specified in the abstract. | Effects of Coenzyme Q10, Tryptophan, and Magnesium Supplementation on Fatigue in Patients with Fibromyalgia - A Randomized Trial. |
| magnesium oxide monohydrate (MOMH) | Increases - greater improvement | sleep quality | Human | eligible subjects | — | A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.cited 2× |
| low magnesium levels | Increases - correlated with increased | sleep latency | Human | — | Not specified. | Does Magnesium Provide a Protective Effect in Crohn's Disease Remission? A Systematic Review of the Literature. |
| magnesium supplementation | Increases - improved | mean sleep quality | Human | patients after open-heart surgery | 500 mg daily (two 250-mg magnesium oxide tablets). | Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.cited 9× |
| magnesium supplementation | No effect - showed an uncertain association | sleep disorders | Human | — | Not specified | The Role of Magnesium in Sleep Health: a Systematic Review of Available Literature.cited 27× |
| magnesium supplementation | Decreases - post-intervention sleep onset latency time was 17.36 min less | sleep onset latency time | Human | older adults with insomnia | — | Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.cited 24× |
| magnesium supplementation | Increases - Total sleep time improved by 16.06 min | Total sleep time | Human | older adults with insomnia | — | Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.cited 24× |
| magnesium supplementation | No effect - was statistically insignificant | Total sleep time | Human | older adults with insomnia | — | Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.cited 24× |
| Magnolia extract and magnesium | Decreases - efficacy | psycho-affective and sleep disturbances in menopause | Human | menopausal women | 60 mg Magnolia bark extract (once daily, as part of ES formulation). | Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause.cited 32× |
| magnesium oxide | No effect - no between-group differences in | quality of sleep | Human | community-dwelling individuals experiencing NLC | Once daily at bedtime (specific amount not mentioned). | Effect of Magnesium Oxide Supplementation on Nocturnal Leg Cramps: A Randomized Clinical Trial.cited 23× |
| Magnesium oxide | Increases - significantly improved | sleep quality | Human | participants with restless legs syndrome | Not specified | Effects of Dietary Supplementation in Patients with Restless Legs Syndrome: A Systematic Review. |
| combination of adrenocorticotropic hormone, magnesium sulfate and either melatonin or placebo | Increases - assessed | Sleep quality | Human | Patients aged 3 months to 2 years with IS | — | Melatonin supplementation for the treatment of infantile spasms: protocol for a randomised placebo-controlled triple-blind trial.cited 3× |
| magnesium-L-threonate | No effect - did not show improvement | sleep disorder | Human | patients who underwent breast cancer procedure | Not specified in the abstract. | A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Therapeutic Effect of Magnesium-L-Threonate Supplementation for Persistent Pain After Breast Cancer Surgery.cited 1× |