8
3
7
↑8
↓3
—7
Evidence suggests Walking mayincreaseSensitivity.
12 studies (18 claims)
Conflicting evidence
Typical effective dose 80 (80–80) %across 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| virtual walking | Decreases - significantly reduced | NP experienced with increased skin sensitivity | Human | individuals with SCI and neuropathic pain | 20 minutes of virtual walking. | Effects of virtual walking on spinal cord injury-related neuropathic pain: A randomized, controlled trial.cited 11× |
| 8 weeks of controlled cycling and walking training at 80% individual Vo2 peak | No effect - could not improve | insulin sensitivity | HumanMolecular | a substantial number of people at risk of developing type 2 diabetes | Training at 80% individual Vo2 peak (specific frequency not mentioned). | TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle.cited 60× |
| 8 weeks of controlled cycling and walking training at 80% individual Vo2 peak | No effect - the failure to increase | insulin sensitivity after training | HumanMolecular | nonresponders in insulin sensitivity (based on the Matsuda index) | Training at 80% individual Vo2 peak (specific frequency not mentioned). | TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle.cited 60× |
| Walking Speed Questionnaire (WSQ) | No effect - sensitivity and specificity were | sensitivity | Human | healthy older adults | Not applicable | Walking speed questionnaire used to estimate gait speed in older adults: Comparisons with testing protocols and diagnostic accuracy. |
| energy expenditure-matched continuous walking training (CWT) | No effect - no changes | insulin sensitivity | Human | individuals with type 2 diabetes | Five sessions per week (60 min/session). | Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomised controlled trial.cited 60× |
| interval walking training (IWT) | Increases - improves | insulin sensitivity | Human | individuals with type 2 diabetes | Five sessions per week (60 min/session). | Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomised controlled trial.cited 60× |
| interval walking training (IWT) | Increases - increased | insulin sensitivity index | Human | individuals with type 2 diabetes | Five sessions per week (60 min/session). | Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomised controlled trial.cited 60× |
| six 20-minute sessions of moderate-intensity walking | Decreases - demonstrated a marginally significant reduction | Anxiety sensitivity (AS) | Human | sedentary young adults with elevated AS | Six 20-minute sessions of moderate-intensity walking. | Pilot randomized clinical trial targeting anxiety sensitivity: effects on physical activity.cited 4× |
| six 20-minute sessions of moderate-intensity walking | No effect - eroded | Anxiety sensitivity (AS) | Human | sedentary young adults with elevated AS | Six 20-minute sessions of moderate-intensity walking. | Pilot randomized clinical trial targeting anxiety sensitivity: effects on physical activity.cited 4× |
| replacing sitting time by standing and walking | Increases - resulted in improved | peripheral insulin sensitivity | Human | overweight women | Sitting less regimen: standing 4 h/day and walking 3 h/day | Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women.cited 18× |
| walking alone | No effect - not significantly improved | peripheral insulin sensitivity (measured by the Cederholm index) | Human | individuals with prediabetes | HIIT (3 × 20-second cycle sprints, 3 times weekly) + walking (>10,000 steps/day) or walking alone. | High-intensity interval training improves insulin sensitivity in individuals with prediabetes. |
| walking alone | Increases - significantly increased | whole-body insulin sensitivity (measured by the Matsuda index) | Human | individuals with prediabetes | HIIT (3 × 20-second cycle sprints, 3 times weekly) + walking (>10,000 steps/day) or walking alone. | High-intensity interval training improves insulin sensitivity in individuals with prediabetes. |
| HIIT + walking | Increases - significantly improved | peripheral insulin sensitivity (measured by the Cederholm index) | Human | individuals with prediabetes | HIIT (3 × 20-second cycle sprints, 3 times weekly) + walking (>10,000 steps/day) or walking alone. | High-intensity interval training improves insulin sensitivity in individuals with prediabetes. |
| HIIT + walking | Increases - significantly increased | whole-body insulin sensitivity (measured by the Matsuda index) | Human | individuals with prediabetes | HIIT (3 × 20-second cycle sprints, 3 times weekly) + walking (>10,000 steps/day) or walking alone. | High-intensity interval training improves insulin sensitivity in individuals with prediabetes. |
| 16-week walking program | No effect - examined the potential relationship | insulin sensitivity (IS: Matsuda) | Human | 29 physically inactive pre- and postmenopausal women with obesity (BMI, 29-35 kg/m²) | Not specified | The relationship between adiposopathy and glucose-insulin homeostasis is not affected by moderate-intensity aerobic training in healthy women with obesity.cited 6× |
| education and home-based pedometer walking program | No effect - did not result in change | high-sensitivity C-reactive protein | Human | human immunodeficiency virus-infected individuals with risk factors of IHD | Not specified (pedometer-based walking program). | Effects of an education and home-based pedometer walking program on ischemic heart disease risk factors in people infected with HIV: a randomized trial.cited 37× |
| Breaking sitting with standing and light-intensity walking | Increases - improved | insulin sensitivity | Human | individuals with type 2 diabetes | Sit Less regimen involved replacing 4.7 hours/day of sitting with standing (2.5 hours) and light-intensity walking (2.2 hours). | Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes.cited 126× |
| Augmentation of walking exercise with HTS | Increases - was more effective than application of sensory TENS in improving | local pain sensitivity at the knee | Human | women with obesity with frequent knee symptoms | Biweekly 30-minute walking sessions with HTS or sensory TENS. | Effect of Neuromuscular Electrical Stimulation During Walking on Pain Sensitivity in Women With Obesity With Knee Pain: A Randomized Controlled Trial.cited 4× |
| Augmentation of walking exercise with HTS | No effect - was not more effective than application of sensory TENS in improving | local pain sensitivity at the wrist | Human | women with obesity with frequent knee symptoms | Biweekly 30-minute walking sessions with HTS or sensory TENS. | Effect of Neuromuscular Electrical Stimulation During Walking on Pain Sensitivity in Women With Obesity With Knee Pain: A Randomized Controlled Trial.cited 4× |
| moderate intensity walking exercise program | Decreases - significantly decreased | high-sensitivity C-reactive protein | Human | postmenopausal women with obesity | Moderate-intensity walking (specific frequency/duration not detailed in abstract). | Moderate intensity walking exercises reduce the body mass index and vascular inflammatory factors in postmenopausal women with obesity: a randomized controlled trial.cited 8× |