The relationship between adiposopathy and glucose-insulin homeostasis is not affected by moderate-intensity aerobic training in healthy women with obesity.
Study Goal
The researchers aimed to examine the relationship between the adiponectin/leptin ratio (a marker of adiposopathy) and insulin resistance/sensitivity before and after a 16-week walking program in inactive women with obesity.
Results Summary
The study investigated changes in insulin resistance, insulin sensitivity, and insulin response following a 16-week walking program, but the abstract does not specify the magnitude or statistical significance of these changes.
Population
29 physically inactive pre- and postmenopausal women with obesity (BMI 29-35 kg/m²).
Effective Dosage
Not specified
Duration
16 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
16-week walking program | neutral | adiponectin/leptin ratio (A/L, a marker of adiposopathy) | 29 physically inactive pre- and postmenopausal women with obesity (BMI, 29-35 kg/m²) | - | examined the potential relationship | #1 |
16-week walking program | neutral | insulin resistance (IR: homeostasis model assessment (HOMA)) | 29 physically inactive pre- and postmenopausal women with obesity (BMI, 29-35 kg/m²) | - | examined the potential relationship | #2 |
16-week walking program | neutral | insulin sensitivity (IS: Matsuda) | 29 physically inactive pre- and postmenopausal women with obesity (BMI, 29-35 kg/m²) | - | examined the potential relationship | #3 |
16-week walking program | neutral | insulin response to an oral glucose tolerance test | 29 physically inactive pre- and postmenopausal women with obesity (BMI, 29-35 kg/m²) | - | examined the potential relationship | #4 |
The contribution of adiposopathy to glucose-insulin homeostasis remains unclear. This longitudinal study examined the potential relationship between the adiponectin/leptin ratio (A/L, a marker of adiposopathy) and insulin resistance (IR: homeostasis model assessment (HOMA)), insulin sensitivity (IS: Matsuda), and insulin response to an oral glucose tolerance test before and after a 16-week walking program, in 29 physically inactive pre- and postmenopausal women with obesity (BMI, 29-35 kg/m