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10
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Evidence suggests Resistance Training maydecreaseInsulin sensitivity.
18 studies (22 claims)
Conflicting evidence
Typical effective dose 300 (300–300) mgacross 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| progressive resistance training (PRT) combined with a protein-enriched diet facilitated through lean red meat | Increases - greater increase in | serum insulin-like growth factor I | Human | elderly women | — | Protein-enriched diet, with the use of lean red meat, combined with progressive resistance training enhances lean tissue mass and muscle strength and reduces circulating IL-6 concentrations in elderly women: a cluster randomized controlled trial.cited 138× |
| essential amino acid (EAA) supplementation and resistance training with decreased energy intake | Increases - increased | insulin-like growth factor-1 (IGF-1) mRNA | Human | men (31-55 years) subjected to an 8 ± 6% energy deficit during recovery | Not specified in the abstract. | Effects of resistance exercise combined with essential amino acid supplementation and energy deficit on markers of skeletal muscle atrophy and regeneration during bed rest and active recovery.cited 38× |
| leucine supplementation and resistance training | No effect - was not affected | insulin sensitivity | Human | nondiabetic prefrail and frail older women | 7.5 g/day of L-alanine (placebo). | Leucine Supplementation Does Not Alter Insulin Sensitivity in Prefrail and Frail Older Women following a Resistance Training Protocol.cited 10× |
| leucine supplementation and resistance training | No effect - No significant time, group, or interaction effects were observed | postprandial areas under the curve of serum insulin | Human | nondiabetic prefrail and frail older women | 7.5 g/day of L-alanine (placebo). | Leucine Supplementation Does Not Alter Insulin Sensitivity in Prefrail and Frail Older Women following a Resistance Training Protocol.cited 10× |
| resistance training | Increases - improved | insulin sensitivity | Human | frail older women | 7.5 g/day of L-alanine (placebo). | Leucine Supplementation Does Not Alter Insulin Sensitivity in Prefrail and Frail Older Women following a Resistance Training Protocol.cited 10× |
| six-week inspiratory resistance training (IRT) | Decreases - significantly reduced | fasting insulin levels | Human | obese individuals | Not available | Six-week inspiratory resistance training ameliorates endurance performance but does not affect obesity-related metabolic biomarkers in obese adults: A randomized controlled trial.cited 7× |
| aerobic plus resistance training (AT+RT) | Decreases - presented lower | homeostasis model assessment-insulin resistance (HOMA-IR) | Human | NAFLD obese adolescents | Not specified (exercise-based intervention). | Long-term effects of aerobic plus resistance training on the adipokines and neuropeptides in nonalcoholic fatty liver disease obese adolescents.cited 64× |
| aerobic plus resistance training (AT+RT) | Decreases - presented lower | insulin | Human | NAFLD obese adolescents | Not specified (exercise-based intervention). | Long-term effects of aerobic plus resistance training on the adipokines and neuropeptides in nonalcoholic fatty liver disease obese adolescents.cited 64× |
| a combination of aerobic-resistance training (CARET) and broccoli supplementation | Decreases - improved | insulin resistance | Human | men with type 2 diabetes mellitus (T2D) | Not specified in the abstract. | The Effects of Aerobic-Resistance Training and Broccoli Supplementation on Plasma Dectin-1 and Insulin Resistance in Males with Type 2 Diabetes.cited 14× |
| High Intensity Interval Resistance Training (HIIRT) protocol | Increases - showed significant improvements in | Insulin Like Growth Factor-1 (IGF-1) | Human | sarcopenic older women | — | Highlighting the effect of reduced training volume on maintaining hormonal adaptations obtained from periodized resistance training in sarcopenic older women. |
| combination HIIT and resistance training | Decreases - were the most effective approaches for reducing | insulin resistance markers | Human | children and adolescents with excess weight | Approximately 900–1200 metabolic equivalent of task (MET) minutes per week. | Exercise and Insulin Resistance Markers in Children and Adolescents With Excess Weight: A Systematic Review and Network Meta-Analysis.cited 16× |
| resistance training (RT) alongside creatine-hydrochloride (Cr-HCl) or creatine monohydrate (CrM) supplementation | Increases - significant increase | insulin-like growth factor-1 (IGF-1) levels | Human | participants with an age range of 18-25 years | Cr-HCl (0.03 g/kg body mass), CrM-loading phase (0.3 g/kg for 5 days, then 0.03 g/kg for 51 days), CrM-without loading phase (0.03 g/kg). | Supplementing With Which Form of Creatine (Hydrochloride or Monohydrate) Alongside Resistance Training Can Have More Impacts on Anabolic/Catabolic Hormones, Strength and Body Composition? |
| 4-week expiratory musculature-targeted resistance training | No effect - this effect was not observed | insulin-like growth factor 1 (IGF-1) levels | Human | healthy young adult men aged between 19 and 35 years | Not specified | Multimodal Adaptations to Expiratory Musculature-Targeted Resistance Training: A Preliminary Study in Healthy Young Adults.cited 2× |
| resistance training (RT) | Decreases - reduced | fasting insulin | Human | insulin-resistant adult women | — | Interindividual responses to different exercise stimuli among insulin-resistant women.cited 11× |
| resistance training | Decreases - improved | fasting insulin | Human | patients with type 2 diabetes mellitus (T2DM) and overweight/obesity | Not specified | Impact of resistance training on cardiometabolic health-related indices in patients with type 2 diabetes and overweight/obesity: a systematic review and meta-analysis of randomised controlled trials.cited 9× |
| resistance training (RT) | No effect - limit conclusions about the impact | fasting insulin concentrations | Human | — | Not specified | Resistance Training as a Countermeasure in Women with Gestational Diabetes Mellitus: A Review of Current Literature and Future Directions.cited 4× |
| resistance training (RT) | Decreases - is effective in reducing | insulin requirement | Human | overweight women | Not specified | Resistance Training as a Countermeasure in Women with Gestational Diabetes Mellitus: A Review of Current Literature and Future Directions.cited 4× |
| resistance training (RT) | No effect - limit conclusions about the impact | insulin resistance | Human | — | Not specified | Resistance Training as a Countermeasure in Women with Gestational Diabetes Mellitus: A Review of Current Literature and Future Directions.cited 4× |
| resistance training | Decreases - significant pooled effect size | insulin | Human | adults with T2DM | Not specified | Effects of resistance training on cardiovascular risk factors in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. |
| resistance training | Increases - time-dependent changes | insulin-like growth factor-1 | Human | young adult men | Not specified in the abstract. | Leucine Metabolites Do Not Enhance Training-induced Performance or Muscle Thickness.cited 23× |
| resistance training | Decreases - resulted in a significant reduction | insulin resistance | Human | individuals in the strength training group | Not specified | The impact of resistance training in patients diagnosed with metabolic dysfunction-associated steatotic liver disease: a systematic review. |
| resistance training | No effect - effect | insulin sensitivity and glycemic control | Human | — | Not specified | Modification of insulin sensitivity and glycemic control by activity and exercise.cited 64× |
| concurrent high-intensity interval training (HIIT) and resistance training (RT) | Increases - improved | insulin sensitivity (HOMA-IR) | Human | patients with type-2 diabetes (T2D) | 3 training sessions per week | Health-related fitness benefits following concurrent high-intensity interval training and resistance training in patients with type-1 diabetes or type-2 diabetes. |