Effects of resistance training on cardiovascular risk factors in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials.
Study Goal
The researchers aimed to determine the effect of resistance training on cardiovascular risk factors in adults with Type 2 diabetes mellitus (T2DM).
Results Summary
Resistance training significantly improved multiple cardiovascular risk factors, including reductions in hemoglobin A1C, fasting blood sugar, insulin, HOMA-IR, triglycerides, body weight, fat percentage, and waist circumference, while increasing high-density lipoprotein.
Population
Adults with Type 2 diabetes mellitus (T2DM).
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
resistance training | decrease | hemoglobin A1C | adults with T2DM | MD = -0.49 | significant pooled effect size | #1 |
resistance training | decrease | fasting blood sugar | adults with T2DM | MD = -11.58 | significant pooled effect size | #2 |
resistance training | decrease | insulin | adults with T2DM | ES = -1.65 | significant pooled effect size | #3 |
resistance training | decrease | HOMA-IR | adults with T2DM | MD = -1.20 | significant pooled effect size | #4 |
resistance training | decrease | triglyceride | adults with T2DM | MD = -18.14 | significant pooled effect size | #5 |
resistance training | increase | high-density lipoprotein | adults with T2DM | MD = 2.71 | significant pooled effect size | #6 |
resistance training | decrease | body weight | adults with T2DM | MD = -0.81 | effective for reducing | #7 |
resistance training | decrease | fat percentage | adults with T2DM | MD = -0.92 | effective for reducing | #8 |
resistance training | decrease | waist circumference | adults with T2DM | MD = -2.14 | effective for reducing | #9 |
resistance training | increase | cardiovascular risk factors | T2DM adults | - | effectively improves | #10 |
AIMS: Type 2 diabetes mellitus (T2DM) is prevalent worldwide, often manageable through lifestyle changes like physical activity. This meta-analysis aimed to determine the effect of resistance training (RT) on cardiovascular risk factors in adults with T2DM. METHODS: Four databases were searched up to March 2024. The mean difference (MD) was calculated by a random effect model with 95% confidence interval (CI). RESULTS: Forty-eight articles were included in the review. There was a significant pooled effect size for the meta-analysis comparing RT vs. control on hemoglobin A1C (MD = -0.49, 95% CI: -0.66, -0.33; P < 0.00001), fasting blood sugar (MD = -11.58, 95% CI: -18.61, -4.55; P = 0.001), insulin (ES = -1.65, 95% CI: -2.87, -0.42; P = 0.008), HOMA-IR (MD = -1.20, 95% CI: -1.85, -0.55; P = 0.0003), triglyceride (MD = -18.14, 95% CI: -30.32, -5.96; P = 0.004), and high-density lipoprotein (MD = 2.71, 95% CI: 0.78, 4.64; P = 0.006). Moreover, RT was effective for reducing body weight (MD = -0.81, 95% CI: -1.50, -0.13; P = 0.02), fat percentage (MD = -0.92, 95% CI: -1.62, -0.22; P = 0.010), and waist circumference (MD = -2.14, 95% CI: -3.00, -1.28; P < 0.00001). CONCLUSION: RT effectively improves cardiovascular risk factors in T2DM adults, suggesting potential as treatment or prevention. Future studies can consider investigating the optimal RT regimen to achieve effective T2DM management in adults.