14
4
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↓14
—4
Evidence suggests Magnesium maydecreaseInflammation.
19 studies (18 claims)
Moderate consensus
Typical effective dose 350 (350–350) mgacross 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| cobalamin and magnesium followed by regular exercise | Decreases - could silence | inflammation signaling pathway | Human | — | Not specified for HIIT; supplementation included vitamin B12 and magnesium (amounts not detailed). | Artificial intelligence analysis to explore synchronize exercise, cobalamin, and magnesium as new actors to therapeutic of migraine symptoms: a randomized, placebo-controlled trial.cited 10× |
| magnesium + vitamin D (MagD; 360 mg magnesium glycinate + 1000 IU vitamin D 3 × daily) | No effect - no statistically significant treatment effects | markers of inflammation | Human | Owt/Ob participants | 360 mg magnesium glycinate + 1000 IU vitamin D3, three times daily | The effect of combined magnesium and vitamin D supplementation on vitamin D status, systemic inflammation, and blood pressure: A randomized double-blinded controlled trial.cited 23× |
| Brain food, e.g. L-tryptophan, antioxidative substances, B vitamins and magnesium | Decreases - are thought to be beneficial | obesity, inflammation and insulin resistance | Human | — | Not specified | Has a mixture of amino acids and micronutrients influence on glucose metabolism and dietary fatty acid pattern in chronic psychosocially stressed persons? A pilot study.cited 1× |
| Magnesium-L-threonate treatment | Decreases - reduced | inflammation | HumanAnimal | a double-transgenic line of Alzheimer's disease model mice expressing the amyloid-β precursor protein and mutant human presenilin 1 (APP/PS1) | Not specified in the abstract. | Magnesium-L-threonate treats Alzheimer's disease by modulating the microbiota-gut-brain axis.cited 9× |
| vitamin D plus magnesium supplementation | Decreases - has beneficial influences | inflammation | Human | obese women with mild to moderate depressive symptoms | — | Randomized study of the effects of vitamin D and/or magnesium supplementation on mood, serum levels of BDNF, inflammation, and SIRT1 in obese women with mild to moderate depressive symptoms.cited 21× |
| magnesium supplementation | Decreases - dose-dependent effects | inflammation | Molecular | in vitro and in vivo | Not specified | Thrombotic microangiopathy: a role for magnesium?cited 5× |
| magnesium supplementation | No effect - no effects | serum lipids, plasma glucose, insulin sensitivity, and low-grade systemic inflammation | Human | overweight and obese subjects | 350 mg daily (three times daily dosing). | Effects of long-term magnesium supplementation on endothelial function and cardiometabolic risk markers: A randomized controlled trial in overweight/obese adults.cited 31× |
| vitamin D and magnesium co-supplementation | No effect - test the effects | inflammation | Human | obese women | — | Effects of vitamin D and/or magnesium supplementation on mood, serum levels of BDNF, inflammatory biomarkers, and SIRT1 in obese women: a study protocol for a double-blind, randomized, placebo-controlled trial.cited 16× |
| vitamin D and magnesium co-supplementation | No effect - may provide a new adjuvant therapy through modulation | inflammation | Human | obese women | — | Effects of vitamin D and/or magnesium supplementation on mood, serum levels of BDNF, inflammatory biomarkers, and SIRT1 in obese women: a study protocol for a double-blind, randomized, placebo-controlled trial.cited 16× |
| magnesium | No effect - evaluate the individual effects | inflammation | Human | 108 obese women | — | Effects of vitamin D and/or magnesium supplementation on mood, serum levels of BDNF, inflammatory biomarkers, and SIRT1 in obese women: a study protocol for a double-blind, randomized, placebo-controlled trial.cited 16× |
| magnesium | Decreases - have anti-inflammatory and anti-depressant effects | inflammation and depressive symptoms | Human | — | — | Effects of vitamin D and/or magnesium supplementation on mood, serum levels of BDNF, inflammatory biomarkers, and SIRT1 in obese women: a study protocol for a double-blind, randomized, placebo-controlled trial.cited 16× |
| Magnesium (Mg) | Decreases - reduces | inflammation | Human | human participants | Not mentioned. | Antioxidant/anti-inflammatory effect of Mgcited 12× |
| magnesium | Decreases - significant improvement | inflammation | Animal | menopausal ovariectomized rats | Not specified. | Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats. |
| magnesium | No effect - dual effect as an anti-inflammatory and bronchodilating agent | inflammation and bronchodilation | Human | — | — | The role of oral magnesium supplements for the management of stable bronchial asthma: a systematic review and meta-analysis.cited 5× |
| Magnesium | Decreases - reduce inflammation | inflammation caused by bacterial toxins | Human | — | Not mentioned | The role of magnesium in the prevention and treatment of dental caries - the latest research. |
| magnesium | Decreases - indirectly by reducing | oxidative stress and chronic low-grade inflammation | Molecular | — | Not provided | Participation of Magnesium in the Secretion and Signaling Pathways of Insulin: an Updated Review.cited 17× |
| Vitamin E supplementation or vitamin E in combination with omega-3 or magnesium | No effect - No significant effect was found | other biomarkers of inflammation or oxidative stress | Human | patients with PCOS | Not specified | A meta-analysis of effects of vitamin E supplementation alone and in combination with omega-3 or magnesium on polycystic ovary syndrome.cited 10× |
| Magnesium oxide | Decreases - has been shown to decrease | inflammation | Human | — | Not specified | Review of complementary and alternative medicine and selected nutraceuticals: background for a pilot study on nutrigenomic intervention in patients with advanced cancer.cited 6× |
| maintaining an adequate dietary intake of vitamin D, iron, fibre, zinc and magnesium | Decreases - may have a beneficial effect on alleviating | inflammation in the body | Human | — | Not specified | Modulation of the Gut Microbiota by Nutrition and Its Relationship to Epigenetics.cited 17× |
| magnesium-zinc-calcium-vitamin D co-supplementation | Decreases - may reduce | biomarkers of inflammation and oxidative stress | Human | women with GDM | Not specified | The effects of magnesium-zinc-calcium-vitamin D co-supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes.cited 90× |
| magnesium-zinc-calcium-vitamin D co-supplementation | No effect - failed to find any significant effect | other biomarkers of inflammation | Human | women with PCOS | 400 mg calcium (plus 100 mg magnesium, 4 mg zinc, and 200 IU vitamin D) twice daily | Magnesium-Zinc-Calcium-Vitamin D Co-supplementation Improves Hormonal Profiles, Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial.cited 38× |
| Potassium and magnesium | Decreases - limit | local inflammation | Molecular | — | Large-volume low-pressure nasal irrigation with undiluted seawater (specific volume and frequency not detailed). | Nasal irrigation: From empiricism to evidence-based medicine. A review.cited 39× |