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Has a mixture of amino acids and micronutrients influence on glucose metabolism and dietary fatty acid pattern in chronic psychosocially stressed persons? A pilot study.

International journal of food sciences and nutrition
January 1, 2016
Norman Bitterlich et al. (5 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether a dietary supplement containing magnesium and other micronutrients could improve cardiometabolic parameters in chronically stressed individuals.

Results Summary

The study found a reduction in fasting serum insulin concentrations in the treatment group after dietary intervention, suggesting potential metabolic benefits. An association was observed between psychological stress scores, baseline insulin levels, and insulin reduction after 12 weeks.

Population

32 patients with chronic stress disorders.

Effective Dosage

Not specified

Duration

12 weeks

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Brain food, e.g. L-tryptophan, antioxidative substances, B vitamins and magnesium
decrease
obesity, inflammation and insulin resistance
-
-
are thought to be beneficial
#1
a specific amino acid mixture with micronutrients
increase
the cardiometabolic situation
chronically stressed persons
-
improves
#2
dietary intervention
decrease
fasting serum insulin concentrations
the treatment group
-
a reduction
#3
our specific dietary supplement
increase
stress management
-
-
improved
#4
our specific dietary supplement
decrease
metabolic dysfunction
-
-
a decrease
#5
Abstract

Brain food, e.g. L-tryptophan, antioxidative substances, B vitamins and magnesium are thought to be beneficial for obesity, inflammation and insulin resistance. In the present pilot study we hypothesised that a specific amino acid mixture with micronutrients improves the cardiometabolic situation of chronically stressed persons. Cardiovascular and metabolic parameters were analysed as per protocol in 32 patients. Chronic stress disorders in the same patients were assessed by a psychological neurological questionnaire (PNF). After dietary intervention a reduction of the fasting serum insulin concentrations occurred in the treatment group. An association was found between PNF values, insulin concentrations at baseline and an insulin reduction after 12 weeks. The results support the use of our specific dietary supplement for improved stress management and a decrease in metabolic dysfunction.

Medical Subject Headings (MeSH)
AdolescentAdultAmino AcidsBlood GlucoseCardiovascular DiseasesDietary FatsDietary SupplementsFatty AcidsFemaleGlucoseHumansMaleMiddle AgedPilot ProjectsRisk FactorsStress, PsychologicalYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality60/10
Citation Metrics
Total Citations1
Citations/Year0.1
Relative Citation Ratio0.06
NIH Percentile3%
Research Impact Scores
APT Score0.05
Weight Score1.29
Normalized Score0.58
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