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Evidence suggests Ketogenic Diet maydecreaseUric acid.
23 studies (29 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| Addition of fructose to the diet | Increases - can increase | postprandial plasma triglyceride and uric acid concentration | Human | normal weight and overweight subjects | Participants consumed 3.3 dL of ASB or SSB with meals. | Metabolic Effects of Replacing Sugar-Sweetened Beverages with Artificially-Sweetened Beverages in Overweight Subjects with or without Hepatic Steatosis: A Randomized Control Clinical Trial.cited 8× |
| diet enriched in medium-chain triglycerides (MCT) | Decreases - led to a decrease | uric acid concentrations | Human | all patients | Not specified | Glycogen storage disease type 1: impact of medium-chain triglycerides on metabolic control and growth.cited 19× |
| low protein diet (LPD) | Decreases - reduction | uric acid | Human | non-dialysis CKD patients | 0.6g/kg/day of protein. | Effects of Low-Protein Diet on lipid and anthropometric profiles of patients with chronic kidney disease on conservative management.cited 6× |
| 45% fish diet | Increases - appreciably improved | concentration of uric acid | Animal | alloxan-induced diabetic Wistar rats | 45% and 55% fish protein-rich diet | Fish protein intake is a novel dietary approach for managing diabetes-associated complications in diabetic Wistar rat model.cited 3× |
| 55% fish diet | Increases - appreciably improved | concentration of uric acid | Animal | alloxan-induced diabetic Wistar rats | 45% and 55% fish protein-rich diet | Fish protein intake is a novel dietary approach for managing diabetes-associated complications in diabetic Wistar rat model.cited 3× |
| low-protein diet (LPD) (0.6 g/kg/day) and inulin (19 g/day) | Decreases - significant reduction | serum uric acid (SUA) | Human | patients treated with LPD and inulin | LPD (0.6 g/kg/day), inulin (19 g/day). | Effect of Low-Protein Diet and Inulin on Microbiota and Clinical Parameters in Patients with Chronic Kidney Disease.cited 38× |
| new omega-3 fatty acid and medium-chain triglyceride-rich formula diet | Decreases - slightly decreased | uric acid levels | Human | patients with severe hypertriglyceridemia | Not specified (formula diet composition details not provided). | Successful treatment of severe hypertriglyceridemia with a formula diet rich in omega-3 fatty acids and medium-chain triglycerides.cited 19× |
| 6-week ketogenic diet | Increases - increased | uric acid levels | Human | women with overweight/obesity | Not specified | Effects of the Ketogenic Diet on Microbiota Composition and Short-Chain Fatty Acids in Women with Overweight/Obesity. |
| very low-calorie ketogenic diet (VLCKD) (Pnk® method) | No effect - did not show differences | uric acid | Human | patients who underwent Roux-en-Y gastric bypass (RYGB) without a reduction of 50% in body weight excess or any weight regain after the surgery | 600-800 kcal/day, low in carbohydrates and lipids (Pnk® method). | Effectiveness and Safety of a Very Low-Calorie Ketogenic Diet on Weight Regain Following Bariatric Surgery.cited 11× |
| diet with 2% LO | Decreases - recorded the lowest | uric acid (UA) bloodstream concentrations | Animal | Japanese quail chicks | 1%, 1.5%, or 2% of diet. | The impacts of dietary inclusion of soybean oil and linseed oil on growth performance, carcass yield, and health status of growing Japanese quail.cited 3× |
| Mediterranean-type diet | Decreases - could play a role in decreasing | serum uric acid concentrations | Human | — | Not specified | Mediterranean diet and risk of hyperuricemia in elderly participants at high cardiovascular risk.cited 57× |
| diet with biofortified curly kale | Decreases - observed variations in, with lower concentrations | uric acid levels | Animal | rats | Biofortified kale enriched with 5,7-diiodo-8-quinolinol (exact dosage not specified) | Comparative Analysis of Iodine Levels, Biochemical Responses, and Thyroid Gene Expression in Rats Fed Diets with Kale Biofortified with 5,7-Diiodo-8-Quinolinol.cited 1× |
| low-protein diet (LPD) plus inulin | Decreases - significant reduction | serum uric acid | Human | CKD patients | LPD (0.6 g/kg/day) plus inulin (19 g/day) for the intervention group; LPD alone for controls. | Prebiotic Therapy with Inulin Associated with Low Protein Diet in Chronic Kidney Disease Patients: Evaluation of Nutritional, Cardiovascular and Psychocognitive Parameters.cited 16× |
| low-protein diet (LPD) without inulin | Decreases - significant reduction | serum uric acid | Human | CKD patients | LPD (0.6 g/kg/day) plus inulin (19 g/day) for the intervention group; LPD alone for controls. | Prebiotic Therapy with Inulin Associated with Low Protein Diet in Chronic Kidney Disease Patients: Evaluation of Nutritional, Cardiovascular and Psychocognitive Parameters.cited 16× |
| low carbohydrate/high fat (LCHF) diet | Increases - increased | uric acid | Human | young and healthy adults | Less than 20g carbohydrates per day. | Effect of low carbohydrate high fat diet on LDL cholesterol and gene expression in normal-weight, young adults: A randomized controlled study.cited 63× |
| flaxseed added to a weight loss diet | Decreases - improvement | levels of uric acid | Human | men with cardiovascular risk factors | 60g of flaxseed powder per day. | Impact of weight loss diet associated with flaxseed on inflammatory markers in men with cardiovascular risk factors: a clinical study.cited 43× |
| aflatoxin B1 (AFB1)-contaminated diet | Decreases - had significantly lower | uric acid | Animal | chickens | 100 ppm and 300 ppm Aloe vera powder mixed into feed | Protective effects of Aloe vera powder supplementation on some quantitative and qualitative characteristics of egg, histopathological changes and serum biochemistry of laying hens fed by Aflatoxin B1.cited 1× |
| diet supplementation with Cetolán III, a combination of KA, inulin, and calcium citrate | Decreases - observed only a slight decrease | uric acid | Human | 76 adult patients diagnosed with CKD stages 3 and 4 and not treated with renal replacement therapy | Not specified | Diet Supplementation with Ketoanalogues, Inulin, and Calcium Citrate in Chronic Kidney Disease: A Retrospective Cohort. |
| acidic diet | Increases - increase | serum uric acid | Human | — | Not specified | Effect of urine pH on uric acid excretion by manipulating food materials.cited 9× |
| acidic diet | Decreases - decrease | uric acid excretion | Human | — | Not specified | Effect of urine pH on uric acid excretion by manipulating food materials.cited 9× |
| alkaline diet | Increases - facilitates | uric acid excretion | Human | — | Not specified | Effect of urine pH on uric acid excretion by manipulating food materials.cited 9× |
| low-carbohydrate and high-fiber diet and education | Decreases - were significantly lower than before | uric acid | Human | patients with nonalcoholic fatty liver disease | Not specified | Impact of a low-carbohydrate and high-fiber diet on nonalcoholic fatty liver disease.cited 12× |
| low-carbohydrate and high-fiber diet and education | Decreases - were lower | uric acid | Human | female patients with nonalcoholic fatty liver disease | Not specified | Impact of a low-carbohydrate and high-fiber diet on nonalcoholic fatty liver disease.cited 12× |
| low-carbohydrate and high-fiber diet and education | Increases - improve | uric acid | Human | patients with nonalcoholic fatty liver disease | Not specified | Impact of a low-carbohydrate and high-fiber diet on nonalcoholic fatty liver disease.cited 12× |
| RP diet | No effect - similar | serum uric acid level | Animal | birds | 0.28% Citrulline in diet | Effects of L-arginine and L-citrulline supplementation in reduced protein diets for broilers under normal and cyclic warm temperature.cited 4× |
| ketogenic diet protocol | No effect - No significant changes were observed | uric acid | Human | 34 male overweight subjects; aged between 25 and 65 years who were overall healthy apart from overweight | Not specified | Effects of n-3 polyunsaturated fatty acids (ω-3) supplementation on some cardiovascular risk factors with a ketogenic Mediterranean diet.cited 52× |
| individualized low-protein diet | Decreases - were significantly lower | uric acid | Human | CKD inpatients | Not specified (individualized low-protein diet). | [Effect of Individualized Low-protein Diet Intervention on Renal Function of Patients with Chronic Kidney Disease].cited 3× |