4
18
2
↑4
↓18
—2
Evidence suggests Ketogenic Diet maydecreaseCardiovascular death.
19 studies (24 claims)
Moderate consensus
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| virgin olive oil (V) diet | Decreases - would reduce | death probability | Animal | male Wistar rats | Not specified | Longevity and Cause of Death in Male Wistar Rats Fed Lifelong Diets Based on Virgin Olive Oil, Sunflower Oil, or Fish Oil.cited 11× |
| virgin olive oil (V) diet | Decreases - effects would be maintained | death probability | Animal | male Wistar rats | Not specified | Longevity and Cause of Death in Male Wistar Rats Fed Lifelong Diets Based on Virgin Olive Oil, Sunflower Oil, or Fish Oil.cited 11× |
| fish oil (F) diet | Decreases - would reduce | death probability | Animal | male Wistar rats | Not specified | Longevity and Cause of Death in Male Wistar Rats Fed Lifelong Diets Based on Virgin Olive Oil, Sunflower Oil, or Fish Oil.cited 11× |
| strict gluten-free diet | Increases - left untreated by | death | Human | patients with Celiac disease | Not available | Twitter Trends for Celiac Disease and the Gluten-Free Diet: Cross-sectional Descriptive Analysis.cited 2× |
| salt content in the daily diet will be measured and shown to study participants; 24-hour salt intake will be estimated in overnight-collected urine and the results shown to the participants; a dietician will assist small group health education classes in cooking meals with less salt | No effect | incidence of CVD events and CVD death | Human | high-CVD-risk patients attending diabetes and hypertension clinics at health centers in Muang District, Chiang Rai province, Thailand | Not specified | Reducing salt intake for prevention of cardiovascular diseases in high-risk patients by advanced health education intervention (RESIP-CVD study), Northern Thailand: study protocol for a cluster randomized trial.cited 12× |
| ketoanalogue-supplemented low-protein diet (sLPD) | Decreases - showed a lower risk of | infection-related death | Human | patients with new-onset end-stage renal disease with permanent dialysis | Not specified | Does a Supplemental Low-Protein Diet Decrease Mortality and Adverse Events After Commencing Dialysis? A Nationwide Cohort Study.cited 14× |
| low-protein diet | Decreases - reduce risk | ESKD and death | Human | patients with moderate to advanced non-dialysis dependent (NDD)-CKD who are metabolically stable | Not specified | Should a low-protein diet and ketoanalogue supplementation be part of the management of advanced chronic kidney disease? |
| low-protein diet (protein intake <0.8 g/kg/day) | Decreases - a trend towards lower | rates of all-cause death | Human | patients with CKD | <0.8 g/kg/day (low-protein diet), <0.4 g/kg/day (very-low-protein diet). | Low-protein diet for conservative management of chronic kidney disease: a systematic review and meta-analysis of controlled trials.cited 149× |
| low-fat/high-carbohydrate diet (Vivonex T.E.N.) | Increases - lived significantly longer until death than | time until death | Human | children with burns ≥ 40% of their total body surface area | Not specified (milk as high-fat diet vs. Vivonex T.E.N. as low-fat/high-carbohydrate diet). | Association between dietary fat content and outcomes in pediatric burn patients.cited 13× |
| low-protein, high-carbohydrate (LPHC) diet | Decreases - decreased | dopaminergic neuronal death | Animal | PD mice | Not specified. | A Low-Protein, High-Carbohydrate Diet Exerts a Neuroprotective Effect on Mice with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson's Disease by Regulating the Microbiota-Metabolite-Brain Axis and Fibroblast Growth Factor 21.cited 14× |
| better adherence to the MIND diet | Decreases - presented a significantly lower risk of all-cause and CV death | all-cause and CV death | Human | patients with ASCVD or stroke | Not specified (diet adherence scored as ≤7.0, 7.5-8.0, and ≥8.5). | Better adherence to the MIND diet is associated with lower risk of all-cause death and cardiovascular death in patients with atherosclerotic cardiovascular disease or stroke: a cohort study from NHANES analysis.cited 8× |
| fish oil (FO) diet during the lactation period | Decreases - significantly decreased | neuronal cell death in the hippocampus and cerebellum | Animal | hypoxia groups | 1 ml/day orally for 12 days. | Proinflammatory factors inhibition and fish oil treatment: A promising therapy for neonatal seizures. |
| ammonia scavengers and protein-restricted diet | No effect - best-accepted therapy | acute hyperammonemia leading to neurological sequelae or death | Human | Patients with X-linked inherited ornithine transcarbamylase deficiency (OTCD) | 2 × 10¹² and 2 × 10¹³ vector genome (vg)/kg | Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys.cited 26× |
| MIND diet score | Decreases - risk of death was reduced | risk of death | Human | 882 participants, mean age 69·5 (±0·8) years, at baseline | Not specified | Adherence to the MIND diet is associated with 12-year all-cause mortality in older adults.cited 18× |
| MIND diet score | Decreases - had a lower risk of death | risk of death | Human | Participants in the top compared with the bottom third of MIND diet score | Not specified | Adherence to the MIND diet is associated with 12-year all-cause mortality in older adults.cited 18× |
| Diet | Increases - largest modifiable risk factors | chronic kidney disease (CKD)-related death and disability | Human | — | Not specified | Stirring the Pot: Can Dietary Modification Alleviate the Burden of CKD?cited 39× |
| MIND diet adherence | Decreases - had a significantly lower risk | all-cause death | Human | participants with T2DM | Not specified (adherence measured by MIND diet score, range 4.5-13). | Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts.cited 2× |
| MIND diet adherence | Decreases - was associated with a significant decrease in the risk | all-cause death | Human | participants without T2DM | Not specified (adherence measured by MIND diet score, range 4.5-13). | Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts.cited 2× |
| MIND diet adherence | Decreases - had a significantly lower risk | CV death | Human | participants with T2DM | Not specified (adherence measured by MIND diet score, range 4.5-13). | Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts.cited 2× |
| MIND diet adherence | No effect - association was not statistically significant | CV death risk | Human | participants without T2DM | Not specified (adherence measured by MIND diet score, range 4.5-13). | Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts.cited 2× |
| ketogenic diet (KD) | Decreases - likely by reducing | inflammation and cell death in the spinal cord | Human | SCI rat model | Not specified | Evaluation of a ketogenic diet for improvement of neurological recovery in individuals with acute spinal cord injury: study protocol for a randomized controlled trial.cited 8× |
| high salt diet | Increases - significantly increased | renal cortical cell death | Animal | ETB-deficient rats | 400 mg/kg/d (intraperitoneal) | Tauroursodeoxycholic acid (TUDCA) abolishes chronic high salt-induced renal injury and inflammation.cited 15× |
| EB diet | Decreases - attenuates | 3-AP-induced neuroinflammation leading to cell death | Animal | 3-AP ataxia model rat | 2% elderberry diet | Elderberry diet enhances motor performance and reduces neuroinflammation-induced cell death in cerebellar ataxia rat models.cited 5× |
| neuroprotection approach with the diet | Decreases - could prevent | cell death | Human | — | Not specified | Bioactive Compounds of the Mediterranean Diet as Nutritional Support to Fight Neurodegenerative Disease.cited 34× |