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4
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Evidence suggests Melatonin maydecreaseOxidative stress.

5 studies (4 claims)

Emerging evidence

Typical effective dose 10 (1010) mgacross 1 dosed study

Study Claims

5 of 5
InterventionDirectionEndpointTypePopulationDosageTitle
melatoninDecreases - demonstrated protective effectsoxidative stress
Human
Not specifiedUnveiling the Protective Roles of Melatonin on Glial Cells in the Battle Against Alzheimer's Disease-Insights from In Vivo and In Vitro Studies.
antioxidantsDecreases - ameliorate the harmful effectoxidative stress
Human
Not specifiedReactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging.cited 680×
melatoninDecreases - reducedoxidative stress
Human
reproductive organ cellsNot specifiedClinical relevance of melatonin in ovarian and placental physiology: a review.cited 63×
melatoninNo effect - effectoxidative stress
Human
obese patients on a calorie-restricted diet10 mg dailyMelatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie-Restricted Diet.cited 47×
melatoninDecreases - reducedoxidative stress
Human
xanthine/xanthine oxidase (X/XO) placental explant modelNot specified in the abstract.Melatonin improves endothelial function in vitro and prolongs pregnancy in women with early-onset preeclampsia.cited 102×