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Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie-Restricted Diet.

Oxidative medicine and cellular longevity
January 1, 2017
Karolina Szewczyk-Golec et al. (8 authors)
Clinical TrialJournal ArticleHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine the effect of melatonin on oxidative stress and adipokine levels in obese patients on a calorie-restricted diet.

Results Summary

The study found that melatonin supplementation in obese patients on a calorie-restricted diet influenced oxidative stress and adipokine levels, though specific outcomes are not detailed in the abstract.

Population

Thirty obese patients

Effective Dosage

10 mg daily

Duration

Not specified

Interactions

None mentioned

Extracted Claims (3)
InterventionDirectionEndpointPopulationDosageImpactClaim #
melatonin
neutral
oxidative stress
obese patients on a calorie-restricted diet
-
effect
#1
melatonin
neutral
adipokine levels
obese patients on a calorie-restricted diet
-
effect
#2
melatonin
neutral
-
Thirty obese patients
a daily dose of 10 mg
supplemented with
#3
Abstract

Obesity is one of the major global health problems. Melatonin deficiency has been demonstrated to correlate with obesity. The aim of the study was to estimate the effect of melatonin on oxidative stress and adipokine levels in obese patients on a calorie-restricted diet. Thirty obese patients were supplemented with a daily dose of 10 mg of melatonin (

Medical Subject Headings (MeSH)
AdipokinesAdultCaloric RestrictionFemaleHumansMaleMelatoninObesityOxidative Stress
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality70/10
Citation Metrics
Total Citations47
Citations/Year5.9
Relative Citation Ratio2.37
NIH Percentile79.4%
Research Impact Scores
APT Score0.75
Weight Score1.95
Normalized Score0.60
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