11
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↓0
—0
Evidence suggests Melatonin mayincreaseAntioxidants.
11 studies (11 claims)
Moderate consensus
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| melatonin administration | Increases - promoting | production of antioxidants | Human | — | Not specified | A new prospective on the role of melatonin in diabetes and its complications.cited 22× |
| melatonin | Increases - up-regulated mRNA expression | antioxidants (SOD1, GPx4 and CAT) | AnimalMolecular | ovine prepubertal cumulus cells | — | Melatonin-induced demethylation of antioxidant genes increases antioxidant capacity through RORα in cumulus cells of prepubertal lambs. |
| melatonin | Increases - more effective than | other naturally occurring antioxidants | Human | — | Not specified | Role of melatonin supplementation in neurodegenerative disorders.cited 39× |
| melatonin treatment | No effect - significant variations was found | antioxidants (total, reduced and oxidized glutathione and ascorbate) content and antioxidant enzymes' activities (i.e., glutathione reductase and ascorbate peroxidase) | Animal | mango trees | 20, 50, 100, and 150 μM melatonin applied three times at different fruit development stages. | Exogenous Melatonin Enhances Moisture Stress Tolerance in Mango (Mangifera indica L.) through Alleviating Oxidative Damages.cited 1× |
| melatonin and its metabolites | Increases - act as | free radical scavengers and antioxidants | Human | — | Not specified | Melatonin in experimental seizures and epilepsy.cited 73× |
| melatonin and its metabolites | Increases - stimulating the synthesis and activity | ROS scavenging enzymes and other antioxidants | Human | — | Not specified | Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective. |
| melatonin and its metabolites | Increases - stimulating the synthesis and activity | ROS scavenging enzymes and other antioxidants | Human | — | Not specified | Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective. |