Ketogenic Diet
→Neuroinflammation

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Evidence suggests Ketogenic Diet maydecreaseNeuroinflammation.

11 studies (8 claims)

Emerging evidence

Study Claims

11 of 11

Intervention	Direction	Endpoint	Type	Population	Dosage	Title
high-fat diet (HFD)	Increases - deleterious effect	neuroinflammation	Animal	AD animal models	Not specified	The effect of dietary fat consumption on Alzheimer's disease pathogenesis in mouse models.cited 22×
high-carbohydrate diet (HCD)	Increases - markedly induced	neuroinflammation	Animal	db/db mice	Not specified	A High-Carbohydrate Diet Induces Cognitive Impairment and Promotes Amyloid Burden and Tau Phosphorylation via PI3K/Akt/GSK-3β Pathway in db/db Mice.
ketogenic diet	No effect - potential role	neuroinflammation	Human	—	Not specified	Ketogenic Diet and Neuroinflammation: Implications for Neuroimmunometabolism and Therapeutic Approaches to Refractory Epilepsy.cited 2×
ketogenic diet	Decreases - associated with neuroprotective and antioxidant effects	neuroinflammation	Molecular	—	Not specified	Impact of the Ketogenic Diet on Neurological Diseases: A Review.cited 2×
Ketogenic diet (KD)	No effect - may modulate	neuroinflammation	Animal	adolescent male C57BL/6 mice with rmTBI	Not specified	Ketogenic Diet Modulates Neuroinflammation via Metabolites from Lactobacillus reuteri After Repetitive Mild Traumatic Brain Injury in Adolescent Mice.cited 14×
ketogenic diet	No effect - effects	neuroinflammation	Human	—	Not specified	Ketogenic Diet: An Effective Treatment Approach for Neurodegenerative Diseases.cited 27×
ketogenic diet (KD)	Decreases - reduced	neuroinflammation	Animal	AD rats	—	The Impact of Ketogenic Diet Consumption on the Sporadic Alzheimer's Model Through MT1/MT2 Regulation.
ketogenic diet (KD)	Decreases - reduced	neuroinflammation	Human	—	Not specified	Ketogenic Diet as a Promising Non-Drug Intervention for Alzheimer's Disease: Mechanisms and Clinical Implications.cited 6×
EB diet	Decreases - attenuates	3-AP-induced neuroinflammation leading to cell death	Animal	3-AP ataxia model rat	2% elderberry diet	Elderberry diet enhances motor performance and reduces neuroinflammation-induced cell death in cerebellar ataxia rat models.cited 5×
HF diet	Decreases - reduced	neuroinflammation	AnimalMolecular	MS mouse model	Not specified (diet composition described as high-fat vs. high-carbohydrate, but exact macronutrient ratios not provided).	High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection.cited 1×
HFSS-combined diet	Increases - caused	neuroinflammation	HumanAnimal	mice during aging	Not specified	A high fat, sugar, and salt Western diet induces motor-muscular and sensory dysfunctions and neurodegeneration in mice during aging: Ameliorative action of metformin.cited 14×