3
14
2
↑3
↓14
—2
Evidence suggests Ketogenic Diet maydecreaseCognitive impairment.
15 studies (19 claims)
Moderate consensus
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| krill oil diet (80 mg/kg/day for one month) | Decreases - prevents | amyloidogenesis and cognitive impairment induced by intraperitoneal lipopolysaccharide (LPS) (250 µg/kg, seven times daily) injections | Animal | AD mice model | 80 mg/kg/day for mice; 50 and 100 µM for EPA and DHA in cell culture. | Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment.cited 35× |
| feeding with a VB6-lacking diet | Increases - showed | cognitive impairment | HumanAnimal | VB6-deficient (VB6(-)) mice | Not specified | Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment.cited 19× |
| Mediterranean diet supplemented with extra-virgin olive oil (MedDiet+EVOO) | Decreases - showed lower MCI | mild cognitive impairment (MCI) | Human | participants at high vascular risk | 30 g/day of mixed nuts. | Virgin olive oil supplementation and long-term cognition: the PREDIMED-NAVARRA randomized, trial.cited 183× |
| EVOO-rich Mediterranean diet | Decreases - had less MCI | mild cognitive impairment (MCI) | Human | participants at high vascular risk | 30 g/day of mixed nuts. | Virgin olive oil supplementation and long-term cognition: the PREDIMED-NAVARRA randomized, trial.cited 183× |
| alcohol and high-fat diet (HFD) administration | Decreases - caused | cognitive impairment | Animal | adult male Wistar rats | 5 mg/kg, intraperitoneally injected daily | 7,8-Dihydroxyflavone alleviated the high-fat diet and alcohol-induced memory impairment: behavioral, biochemical and molecular evidence.cited 25× |
| Chinese version of the MIND (cMIND) diet | Decreases - associated with a reduced risk | cognitive impairment | Human | older Chinese individuals | Not specified | Association of adherence to the Chinese version of the MIND diet with reduced cognitive decline in older Chinese individuals: Analysis of the Chinese Longitudinal Healthy Longevity Survey.cited 3× |
| Mediterranean-Dietary Approaches to Stop Hypertension (DASH) diet intervention for Neurodegenerative Delay (MIND) | Decreases - associated with a reduced risk | cognitive impairment | Human | North American and Oceanian populations | Not specified | Association of adherence to the Chinese version of the MIND diet with reduced cognitive decline in older Chinese individuals: Analysis of the Chinese Longitudinal Healthy Longevity Survey.cited 3× |
| Adherence to the cMIND diet | Decreases - associated with lower risks | cognitive impairment | Human | older Chinese individuals | Not specified | Association of adherence to the Chinese version of the MIND diet with reduced cognitive decline in older Chinese individuals: Analysis of the Chinese Longitudinal Healthy Longevity Survey.cited 3× |
| Mediterranean diet (MD) pattern | Decreases - was associated with a lower risk of | cognitive impairment | Human | Italian urban sample aged ≥ 65 years | Not specified | Mediterranean Diet and Cognitive Status in Free-Living Elderly: A Cross-Sectional Study in Northern Italy.cited 25× |
| 0.5% cuprizone diet | Increases - causes | cognitive impairment and neurodegeneration | Animal | adult wistar rats | 100 mg/kg body weight, administered once daily via oral gavage. | Neurotherapeutic and antioxidant response of D-ribose-L-Cysteine nutritional dietary supplements on Alzheimer-type hippocampal neurodegeneration induced by cuprizone in adult male wistar rat model.cited 6× |
| gluten free diet | Decreases - potentially protective effect | cognitive impairment | Human | patients with CD or NCGS | Not specified | Cognitive impairment in celiac disease and non-celiac gluten sensitivity: review of literature on the main cognitive impairments, the imaging and the effect of gluten free diet.cited 24× |
| adherence to the MIND diet at baseline | No effect - was not associated with | mild cognitive impairment (MCI) at MoCA < 24 | Human | adults ≥70 years | Not specified | Adherence to the MIND diet and the odds of mild cognitive impairment in generally healthy older adults: The 3-year DO-HEALTH study. |
| adherence to the MIND diet at baseline | No effect - was not associated with | mild cognitive impairment (MCI) at MoCA < 26 | Human | adults ≥70 years | Not specified | Adherence to the MIND diet and the odds of mild cognitive impairment in generally healthy older adults: The 3-year DO-HEALTH study. |
| Mediterranean diet | Decreases - expose the relationship | cognitive impairment | Human | — | Not specified | Mild cognitive impairment, from theory to practical intervention: "Camminando e leggendo… ricordo" (Walking and reading… I remember), an action plan. The Treviso Dementia (TREDEM) Registry.cited 5× |
| Mediterranean diet | Decreases - well-known effects | cognitive impairment | Human | — | Not specified | Botanicals and phytochemicals active on cognitive decline: The clinical evidence.cited 40× |
| Consumption of high fat diet (HFD) | Increases - increases risk | cognitive impairment and memory deficit | Animal | — | 100, 200, or 500 mg/kg/d | Protective effects of krill oil on high fat diet-induced cognitive impairment by regulation of oxidative stress.cited 2× |
| MIND diet | Decreases - higher adherence correlated with reduced cognitive impairment | cognitive impairment | Human | elderly individuals in Pakistan | Not specified | The relationship between levels of physical activity, adherence to the MIND diet, and cognitive impairment in adults aged 65 years or older in Pakistan. |