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Evidence suggests Creatine haslittle to no effecton Safety.

2 studies (2 claims)

Exact normalized-entity scope. Exact scope. Claims must match the selected normalized intervention and endpoint IDs; signal links are not expanded. Direction describes the stored endpoint phrase and is not a benefit/harm judgement.
2 of 2
InterventionDirectionEndpointTypePopulationDosageTitle
creatineNo effect - no safety concernssafety
Human
Six participants with ALS5, 10, and 15 g twice daily (b.i.d.).A phase I, pharmacokinetic, dosage escalation study of creatine monohydrate in subjects with amyotrophic lateral sclerosis.cited 28×
creatineNo effect - considered safe and without significant adverse effectssafety
Human
Variable, with multiple regimens showing benefits (specific amounts not detailed).Creatine Use in Sports.cited 47×