15
2
↑15
↓0
—2
Evidence suggests Caffeine mayincreaseEnergy expenditure.
12 studies (17 claims)
Moderate consensus
Typical effective dose 101.5 (52.25–150.75) mgacross 2 dosed studies
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| acute ingestion of a novel thermogenic supplement (OxyShred) containing 300 mg of caffeine and 3 g of acetyl-L-carnitine | Increases - stimulates increases | resting energy expenditure (REE) | Human | forty-six adults | — | The Effects of Two Servings of a Thermogenic Supplement on Metabolism, Hemodynamic Variables, and Mood State Outcomes in Young Overweight Adults. |
| EGCG + caffeine | No effect - had no influence | energy expenditure | Animal | C. elegans | Not specified | Effects of epigallocatechin gallate, caffeine, and their combination on fat accumulation in high-glucose diet-fed Caenorhabditis elegans.cited 3× |
| caffeine-polyphenol supplement | Increases - resulted in significantly greater | energy expenditure at rest | Human | 12 subjects (male: n = 11; female: n = 1) | Not specified in the abstract. | Dietary Caffeine and Polyphenol Supplementation Enhances Overall Metabolic Rate and Lipid Oxidation at Rest and After a Bout of Sprint Interval Exercise.cited 5× |
| caffeine-polyphenol supplement | Increases - resulted in significantly greater | energy expenditure post-SIE | Human | 12 subjects (male: n = 11; female: n = 1) | Not specified in the abstract. | Dietary Caffeine and Polyphenol Supplementation Enhances Overall Metabolic Rate and Lipid Oxidation at Rest and After a Bout of Sprint Interval Exercise.cited 5× |
| caffeine (200 mg) | No effect - was not affected | energy expenditure | Human | obese men | 200 mg caffeine, taken orally for 3 days. | Epigallocatechin-3-gallate and postprandial fat oxidation in overweight/obese male volunteers: a pilot study.cited 50× |
| caffeine | Increases - proposed beneficial role | energy expenditure | Human | — | Not specified. | Caffeine and cardiovascular diseases: critical review of current research.cited 57× |
| caffeine | Increases - may act synergistically with GTC to increase | energy expenditure | Human | — | 270 mg to 1200 mg/day. | Antiobesity effects of green tea catechins: a mechanistic review.cited 238× |
| caffeine | Increases - increased | total energy expenditure | Human | fifteen young and healthy participants (11 men and 4 women) | — | Caffeine increases exercise intensity and energy expenditure but does not modify substrate oxidation during 1 h of self-paced cycling.cited 2× |
| mixed flavonoid-caffeine (MFC) supplement | No effect - acute effect of ingesting | energy expenditure (EE) | Human | premenopausal women | — | Acute Ingestion of a Mixed Flavonoid and Caffeine Supplement Increases Energy Expenditure and Fat Oxidation in Adult Women: A Randomized, Crossover Clinical Trial.cited 6× |
| caffeine exercise trial (EX+CAF) | Increases - resulted in significantly greater | energy expenditure | Human | Fourteen recreationally active participants | 2 × 3 mg/kg of caffeine (administered 90 min before and 30 min after exercise). | Caffeine consumption around an exercise bout: effects on energy expenditure, energy intake, and exercise enjoyment.cited 29× |