4
2
6
↑4
↓2
—6
Evidence suggests Vitamin D haslittle to no effecton Cognitive function.
12 studies (12 claims)
Emerging evidence
Typical effective dose 25200 (12800–37600) IUacross 2 dosed studies
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| Co-administration of probiotics and vitamin D | Increases - has beneficial effects on the improvement | cognitive function | Human | schizophrenic patients | 400 IU vitamin D (frequency not specified). | Co-administration of probiotic and vitamin D significantly improves cognitive function in schizophrenic patients: A double-blinded randomized controlled trial.cited 10× |
| maternal vitamin D deficiency | Decreases - showed lower cognitive function | cognitive function | Human | children | Not specified | Association between maternal nutritional status in pregnancy and offspring cognitive function during childhood and adolescence; a systematic review.cited 84× |
| Vitamin D supplementation | Increases - improves | cognitive function | Human | TBI patients | Not available | Supplement and nutraceutical therapy in traumatic brain injury. |
| vitamin D supplementation | No effect - showed inconsistent results | cognitive function | Human | — | Not specified | Serum 25(OH)D and Cognition: A Narrative Review of Current Evidence.cited 15× |
| vitamin D supplementation | No effect - failed to find evidence suggesting a causal association | cognitive function | Human | adults | Not specified | Vitamin D Supplementation and Cognition in Adults: A Systematic Review of Randomized Controlled Trials.cited 20× |
| vitamin D supplementation | Decreases - suggests a real role in the prevention of cognitive decay | cognitive function | Human | healthy subjects | Not specified | The Potential Role of Vitamin D Supplementation in Cognitive Impairment Prevention.cited 3× |
| lower serum concentrations of vitamin D | No effect - no strong evidence that are associated with worsening | cognitive function | Human | individuals with T2DM | 5000 IU/week (low dose) and 50,000 IU/week (high dose). | Association of vitamin D and cognition in people with type 2 diabetes: a systematic review.cited 1× |
| lower serum concentrations of vitamin D-binding protein | No effect - no strong evidence that are associated with worsening | cognitive function | Human | individuals with T2DM | 5000 IU/week (low dose) and 50,000 IU/week (high dose). | Association of vitamin D and cognition in people with type 2 diabetes: a systematic review.cited 1× |
| vitamin D | Increases - improve | cognitive function and behavior | Human | brain disorders | Not specified | Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior.cited 298× |
| 1,000 mg of calcium carbonate combined with 400 IU of vitamin D(3) | No effect - no significant differences | domain-specific cognitive function | Human | women aged 65 and older without probable dementia at baseline | 1,000 mg of calcium carbonate combined with 400 IU of vitamin D3 daily. | Calcium and vitamin D supplementation and cognitive impairment in the women's health initiative.cited 122× |
| 1,000 mg of calcium carbonate combined with 400 IU of vitamin D(3) | No effect - no significant differences | global cognitive function | Human | women aged 65 and older without probable dementia at baseline | 1,000 mg of calcium carbonate combined with 400 IU of vitamin D3 daily. | Calcium and vitamin D supplementation and cognitive impairment in the women's health initiative.cited 122× |
| a targeted, multi-component resistance and impact-loading exercise programme together with a daily protein-, calcium- and vitamin D-enriched supplement | No effect - determine the effects | cognitive function | Human | men treated with ADT for prostate cancer | Not specified | Efficacy of a multi-component exercise programme and nutritional supplementation on musculoskeletal health in men treated with androgen deprivation therapy for prostate cancer (IMPACT): study protocol of a randomised controlled trial.cited 18× |
| Physical exercise, cognitive training, and vitamin D | Increases - have the potential to enhance | cognitive function and mobility | Human | older adults, especially in pre-dementia states such as Mild Cognitive Impairment (MCI) | Not specified for resistance training; vitamin D supplementation at 3 × 10,000 IU/week. | SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment.cited 46× |
| vitamin D status | No effect - suggest a link between | cognitive function | Human | — | Not specified | Vitamin D, Cognition and Alzheimer's Disease: The Therapeutic Benefit is in the D-Tails.cited 124× |