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2
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Evidence suggests Semaglutide maydecreaseMuscle mass.
2 studies (3 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| highly effective incretin-mimetic drugs (IMDs), particularly semaglutide and tirzepatide | Decreases - lost 10% or more of their muscle mass | muscle mass | Human | clinical trial participants receiving IMDs for the treatment of obesity | — | Strategies for minimizing muscle loss during use of incretin-mimetic drugs for treatment of obesity. |
| highly effective incretin-mimetic drugs (IMDs), particularly semaglutide and tirzepatide | Decreases - loss of skeletal muscle mass and function that can accompany rapid substantial weight reduction | skeletal muscle mass and function | Human | patients | — | Strategies for minimizing muscle loss during use of incretin-mimetic drugs for treatment of obesity. |