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3
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Evidence suggests Psilocybin maydecreaseMood.
4 studies (5 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| ayahuasca, psilocybin and lysergic acid diethylamide (LSD) | Decreases - may have antidepressive, anxiolytic, and antiaddictive properties | mood and anxiety disorders and drug dependence | Human | patients | Not specified | Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years.cited 163× |
| ayahuasca, psilocybin and LSD | Decreases - may be useful pharmacological tools for the treatment | drug dependence, and anxiety and mood disorders | Human | treatment-resistant patients | Not specified | Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years.cited 163× |
| psilocybin | Increases - associated with increased | positive mood | Animal | patients with depression | Not specified | Psilocybin increases optimistic engagement over time: computational modelling of behaviour in rats.cited 4× |