2
1
2
↑2
↓1
—2
Evidence suggests Psilocybin haslittle to no effecton Memory.
2 studies (5 claims)
Conflicting evidence
Typical effective dose 27.5 (26.25–28.75) mgacross 2 dosed studies
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| psilocybin therapy | Decreases - improved | performance in Spatial Working Memory | Human | people with mild to moderate stage PD plus depression and/or anxiety | One 10 mg dose followed by one 25 mg dose, administered with psychotherapy. | Psilocybin therapy for mood dysfunction in Parkinson's disease: an open-label pilot trial. |
| Psilocybin | No effect - less pronounced | episodic memory | Human | — | Macrodoses ranging from 45 μg/kg to 30 mg/70 kg. | Impact of psilocybin on cognitive function: A systematic review.cited 5× |
| Psilocybin | Increases - showed promise in improving | specific memory types such as semantic associations | Human | — | Macrodoses ranging from 45 μg/kg to 30 mg/70 kg. | Impact of psilocybin on cognitive function: A systematic review.cited 5× |
| Psilocybin | No effect - less pronounced | verbal memory | Human | — | Macrodoses ranging from 45 μg/kg to 30 mg/70 kg. | Impact of psilocybin on cognitive function: A systematic review.cited 5× |
| Psilocybin | Increases - improvements | working memory | Human | patients with treatment-resistant depression (TRD) | Macrodoses ranging from 45 μg/kg to 30 mg/70 kg. | Impact of psilocybin on cognitive function: A systematic review.cited 5× |