3
↑0
↓3
—0
Evidence suggests Nicotine maydecreaseWound healing.
2 studies (3 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| nicotine | Decreases - might inhibit | bone matrix-related gene expressions required for wound healing | Animal | — | — | Effects of nicotine on gene expression and osseointegration in rats. |
| nicotine | Decreases - affected | bone wound healing around the implant after placement | Animal | rats | — | Effects of nicotine on gene expression and osseointegration in rats. |
| nicotine | Decreases - impairs | wound healing | HumanMolecular | — | 10^(-5) M for single, double, or triple antioxidant combinations. | Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells.cited 25× |