2
1
↑2
↓0
—1
Evidence suggests Nicotine mayincreaseCognitive function.
3 studies (3 claims)
Emerging evidence
Typical effective dose 1.05 (0.57–1.52) mgacross 2 dosed studies
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| nicotine supplementation | Increases - increasing | cognitive function | Human | archery athletes | 2 mg nicotine gum (single dose). | Nicotine supplementation enhances simulated game performance of archery athletes.cited 5× |
| single doses of nicotine | Increases - may be able to enhance | relevant aspects of cognitive function and/or alertness | Human | — | — | Phytochemicals for Improving Aspects of Cognitive Function and Psychological State Potentially Relevant to Sports Performance.cited 22× |
| chronic nicotine administration | No effect - showed no significant differences | cognitive function | Animal | 6-month-old cohort (DKO and WT mice) | 100 μg/ml oral nicotine treatment | Age- and Genotype-Dependent Effects of Chronic Nicotine on Presenilin1/2 Double Knockout Mice: From Behavior to Molecular Pathways. |