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4
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Evidence suggests Melatonin maydecreaseSleep onset.
3 studies (6 claims)
Typical dose 6 mg
Exact normalized-entity scope. Exact scope. Claims must match the selected normalized intervention and endpoint IDs; signal links are not expanded. Direction describes the stored endpoint phrase and is not a benefit/harm judgement.
6 of 6
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| melatonin | Increases - showed improvement | sleep onset | Human | children with ADHD and insomnia | 3 to 6 mg administered within a few hours of bedtime. | Melatonin treatment for insomnia in pediatric patients with attention-deficit/hyperactivity disorder.cited 61× |
| melatonin | Increases - significantly advanced | sleep onset (SO) | Human | children between 6 and 12 years with chronic sleep onset insomnia (CSOI) | 0.05, 0.1, and 0.15 mg/kg melatonin administered once daily. | Dose finding of melatonin for chronic idiopathic childhood sleep onset insomnia: an RCT.cited 67× |
| melatonin | Decreases - correlated significantly with treatment effect | sleep onset (SO) | Human | — | 0.05, 0.1, and 0.15 mg/kg melatonin administered once daily. | Dose finding of melatonin for chronic idiopathic childhood sleep onset insomnia: an RCT.cited 67× |
| melatonin | Decreases - can advance the time of sleep onset | sleep onset | Human | — | Not specified | What do we really know about the safety and efficacy of melatonin for sleep disorders?cited 13× |
| melatonin | Decreases - effect is modest and variable | sleep onset | Human | — | Not specified | What do we really know about the safety and efficacy of melatonin for sleep disorders?cited 13× |
| melatonin | Decreases - appears to have the greatest impact on sleep onset | sleep onset | Human | children with neurodevelopmental disabilities | Not specified | What do we really know about the safety and efficacy of melatonin for sleep disorders?cited 13× |