3
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—0
Evidence suggests Melatonin mayincreaseSleep efficiency.
3 studies (3 claims)
Emerging evidence
Typical effective dose 3 (3–4.5) mgacross 3 dosed studies
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| melatonin | Increases - improved | sleep efficiency | Human | patients with CF | 3 mg melatonin daily. | Melatonin improves sleep and reduces nitrite in the exhaled breath condensate in cystic fibrosis--a randomized, double-blind placebo-controlled study.cited 26× |
| 6 mg oral melatonin | Increases - significantly increased | sleep efficiency | Human | patients in breast cancer surgery | 6 mg approximately 60 minutes before bedtime. | Effect of Melatonin on Sleep in the Perioperative Period after Breast Cancer Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.cited 46× |
| melatonin | Increases - was significantly higher than among those given the placebo | sleep efficiency | Human | paediatric patients suffering from severe epileptic disorders | 3 mg nightly. | Normalization of the sleep-wake pattern and melatonin and 6-sulphatoxy-melatonin levels after a therapeutic trial with melatonin in children with severe epilepsy.cited 35× |