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Evidence suggests Melatonin mayincreaseMitochondrial function.
11 studies (9 claims)
Typical dose 100 mg
Exact normalized-entity scope. Exact scope. Claims must match the selected normalized intervention and endpoint IDs; signal links are not expanded. Direction describes the stored endpoint phrase and is not a benefit/harm judgement.
6 of 11
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| Melatonin | No effect - protective effects | mitochondrial function | Human | — | Not specified | Melatonin in septic shock: some recent concepts.cited 64× |
| melatonin | Increases - have a significant protective effect | mitochondrial function | Human | — | 50-100 mg/day (proposed for future clinical trials). | Inflammaging, Metabolic Syndrome and Melatonin: A Call for Treatment Studies.cited 68× |
| melatonin | Increases - improves | mitochondrial function | Human | critically ill patients | Not mentioned | Oxidative stress in sepsis: Pathophysiological implications justifying antioxidant co-therapy.cited 159× |
| melatonin | Increases - improves | mitochondrial function | Human | diabetic patients | Not specified | New insights into the role of melatonin in diabetic cardiomyopathy.cited 14× |
| melatonin | Increases - exerts a beneficial effect on mitochondrial function to mitigate ferroptosis | mitochondrial function | AnimalMolecular | ST cells | — | Melatonin regulates mitochondrial function to alleviate ferroptosis through the MT2/Akt signaling pathway in swine testicular cells. |
| melatonin | Increases - preserving | mitochondrial function | Molecular | cardiac cells | Not specified | Insight into the cardioprotective effects of melatonin: shining a spotlight on intercellular Sirt signaling communication.cited 1× |