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Evidence suggests Melatonin mayincreaseAppetite.
6 studies (8 claims)
Emerging evidence
Typical effective dose 20 (12.5–20) mgacross 3 dosed studies
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| melatonin 20 mg | No effect - found to be nonsignificant | ESAS lack of appetite | Human | patients with breast cancer undergoing RT | 20 mg orally, starting the night before radiotherapy initiation until 2 weeks post-radiotherapy. | Melatonin Supplementation for Cancer-Related Fatigue in Patients With Early Stage Breast Cancer Receiving Radiotherapy: A Double-Blind Placebo-Controlled Trial.cited 6× |
| melatonin | Increases - appetite stimulant | appetite | Human | patients with cachexia and body wasting | Not specified | Treatment of cachexia: an overview of recent developments. |
| melatonin | Increases - appetite stimulant | appetite | Human | patients with cachexia and body wasting | Not specified | Treatment of cachexia: an overview of recent developments. |
| melatonin | Increases - appetite stimulant | appetite | Human | patients with cachexia and body wasting | Not specified | Treatment of cachexia: An overview of recent developments. |
| melatonin | Increases - appetite stimulant | appetite | Human | patients with cachexia and body wasting | Not specified | Treatment of cachexia: An overview of recent developments. |
| melatonin | Increases - significantly increased | appetite | Human | — | Not specified | Melatonin as a Novel Drug to Improve Cardiac Function and Quality of Life in Heart Failure Patients: A Systematic Review and Meta-Analysis. |
| melatonin | No effect - did not improve | appetite | Human | cachectic patients with advanced cancer | 20 mg at night | Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.cited 72× |
| combined administration of fluoxetine and melatonin | Decreases - was useful option to treat | mood, sleep and appetite disorders | Human | postmenopausal women | 5 mg melatonin in the evening, daily. | Effects of fluoxetine and melatonin on mood, sleep quality and body mass index in postmenopausal women.cited 38× |