5
2
1
↑5
↓2
—1
Evidence suggests MDMA mayincreaseSleep quality.
4 studies (8 claims)
Emerging evidence
Typical effective dose 100 (100–100) mgacross 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| MDMA-assisted psychotherapy | Increases - improved | self-reported sleep quality (SQ) | Human | individuals with PTSD | — | Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder.cited 27× |
| MDMA-assisted psychotherapy | Increases - had improved | self-reported sleep quality (SQ) | Human | — | — | Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder.cited 27× |
| MDMA-assisted psychotherapy | Increases - further significant gains | self-reported sleep quality (SQ) | Human | — | — | Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder.cited 27× |
| MDMA-assisted psychotherapy | Decreases - beneficial effects | sleep disturbances (SDs) | Human | individuals with PTSD | — | Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder.cited 27× |
| active MDMA (75-125 mg) | Increases - showed more improvement | self-reported sleep quality (SQ) | Human | participants in the active dose group | — | Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder.cited 27× |
| MDMA-assisted psychotherapy | No effect - may be promising options | sleep outcomes | Human | patients with PTSD | Not specified | Pharmacotherapy for sleep disturbances in post-traumatic stress disorder (PTSD): A network meta-analysis.cited 1× |
| MDMA | Increases - Deficits also occur in | sleep apnoea | Human | — | Not specified | Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research.cited 112× |
| MDMA | Decreases - Deficits also occur in | sleep architecture | Human | — | Not specified | Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research.cited 112× |
| MDMA | No effect - did not change | the impairing effects of sleep loss | Human | recreational MDMA users | Single evening doses of 0, 25, 50, and 100 mg MDMA | MDMA (ecstasy) effects on actual driving performance before and after sleep deprivation, as function of dose and concentration in blood and oral fluid.cited 17× |