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Evidence suggests MDMA maydecreasePain.
2 studies (4 claims)
Emerging evidence
Typical effective dose 175 (175–175) mgacross 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| MDMA | Increases - Deficits also occur in | pain | Human | — | Not specified | Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research.cited 112× |
| MDMA at high doses (150-175 mg) and repeated low doses (12.5-25 mg) | Decreases - exhibited marked improvements | neuropathic pain | Human | A 64-year-old male patient who suffered from traumatic life experiences and neuropathic pain after oncological chemotherapy | High doses (150-175 mg) and repeated low doses (12.5-25 mg) of MDMA. | Treatment of neuropathic pain with repeated low-dose MDMA: a case report. |
| MDMA at high doses (150-175 mg) and repeated low doses (12.5-25 mg) | Decreases - improvements were sustained even after stopping repeated MDMA treatment | neuropathic pain | Human | A 64-year-old male patient who suffered from traumatic life experiences and neuropathic pain after oncological chemotherapy | High doses (150-175 mg) and repeated low doses (12.5-25 mg) of MDMA. | Treatment of neuropathic pain with repeated low-dose MDMA: a case report. |
| low doses of MDMA | Decreases - documents benefits | a pain disorder | Human | — | High doses (150-175 mg) and repeated low doses (12.5-25 mg) of MDMA. | Treatment of neuropathic pain with repeated low-dose MDMA: a case report. |