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Evidence suggests Ketogenic Diet mayincreaseLifespan.
6 studies (7 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| addition of 10mg/ml BTE into diet | Increases - extended | maximum lifespan | Animal | — | 10 mg/ml BTE in diet. | Black tea theaflavins extend the lifespan of fruit flies.cited 41× |
| high-carbohydrate diet from weaning to adulthood | Increases - may potentially extend | lifespan | Animal | rats | Not specified (ad libitum feeding). | Longevity extension in rats via improved redox homeostasis with high carbohydrate diet intervention from weaning to adulthood: a comprehensive multi-omics study. |
| high-carbohydrate diet (HC) | Increases - activated the expression and upregulation of | lifespan-related proteins Foxo3a/Sirt3 and the key metabolic enzyme GPX-4 | Animal | rats | Not specified (ad libitum feeding). | Longevity extension in rats via improved redox homeostasis with high carbohydrate diet intervention from weaning to adulthood: a comprehensive multi-omics study. |
| polyunsaturated fatty acid (PUFA)-enriched high-fat diet (HFD) | Increases - significantly extended | lifespan | Animal | Ndufs4 KO mice | Not specified (PUFA-enriched HFD composition details not provided). | The therapeutic potential of a polyunsaturated fatty acid-enriched high-fat diet in Leigh syndrome: Insights from a preclinical model. |
| diet supplementation with prebiotics, probiotics and synbiotics, or fecal microbiota transplantation | Increases - could extend | our healthy lifespan | Human | — | Not specified | Gut microbiota and old age: Modulating factors and interventions for healthy longevity.cited 63× |
| ketogenic diet | Increases - extended lifespan | lifespan | HumanAnimal | mouse | Not specified | The role of lipid metabolism in aging, lifespan regulation, and age-related disease.cited 272× |
| epigenetic diet (ED) | Increases - introduces bioactive medicinal chemistry compounds | human lifespan | Human | — | Not mentioned | Medicinal chemistry of the epigenetic diet and caloric restriction.cited 49× |