20
2
7
↑20
↓2
—7
Evidence suggests Ketogenic Diet mayincreaseEfficacy.
25 studies (29 claims)
Moderate consensus
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| classic ketogenic diet (cKD) | No effect - has absolute indications including | efficacy and safety | Human | patients with pyruvate dehydrogenase complex deficiency (PDCD) | Not specified | Clinical Efficacy and Safety of the Ketogenic Diet in Patients with Genetic Confirmation of Drug-Resistant Epilepsy. |
| classic ketogenic diet (cKD) | No effect - has absolute indications including | efficacy and safety | Human | patients with glucose transporter type 1 deficiency syndrome (GLUT1DS) | Not specified | Clinical Efficacy and Safety of the Ketogenic Diet in Patients with Genetic Confirmation of Drug-Resistant Epilepsy. |
| a Mediterranean diet | No effect - categorised the efficacy | efficacy | Human | people with hypertension | Not specified | Primary prevention of CVD: modification of diet in people with hypertension.cited 8× |
| a low-salt diet (including the DASH diet) | No effect - categorised the efficacy | efficacy | Human | people with hypertension | Not specified | Primary prevention of CVD: modification of diet in people with hypertension.cited 8× |
| long-term 'adapted' low FODMAP diet | No effect - emerging data | efficacy | Human | individuals with IBS | Not specified | The role of diet in irritable bowel syndrome: implications for dietary advice.cited 37× |
| low FODMAP diet | Increases - demonstrating the efficacy | efficacy | Human | individuals with IBS | Not specified | The role of diet in irritable bowel syndrome: implications for dietary advice.cited 37× |
| 4-food elimination diet (dairy, wheat/gluten cereals, egg, and legumes) | Increases - were lately developed with good efficacy rates | efficacy rates | Human | — | Not specified (elimination diets involved complete avoidance of dairy). | Treatment of eosinophilic esophagitis with diets.cited 8× |
| 2-food elimination diet (dairy and milk/gluten) | Increases - were lately developed with good efficacy rates | efficacy rates | Human | — | Not specified (elimination diets involved complete avoidance of dairy). | Treatment of eosinophilic esophagitis with diets.cited 8× |
| Curcumin Boswellia Phytosome (CBP) and Low FODMAP diet (LFD) | Increases - showed a significantly better | global assessment of efficacy (GAE) | Human | IBS subjects with small bowel dysbiosis | 500 mg twice daily of CBP. | Beneficial Effects on Abdominal Bloating with an Innovative Food-Grade Formulation of Curcuma longa and Boswellia serrata Extracts in Subjects with Irritable Bowel Syndrome and Small Bowel Dysbiosis.cited 11× |
| A poor diet | Decreases - decreasing | efficacy of chemotherapy in destroying malignant cells | Human | — | Not specified | Micronutrients Importance in Cancer Prevention-Vitamins.cited 1× |
| low sodium diet | Increases - enhances | efficacy | Animal | — | Not specified. | ACE inhibition has adverse renal effects during dietary sodium restriction in proteinuric and healthy rats.cited 44× |
| a 2-food elimination diet (dairy and gluten-containing cereals) | Increases - have lately developed with good efficacy rates | efficacy rates | Human | — | Not specified | Dietary therapy for eosinophilic esophagitis.cited 43× |
| a 4-food elimination diet (dairy, gluten-containing cereals, egg, and legumes) | Increases - have lately developed with good efficacy rates | efficacy rates | Human | adults | Not specified | Dietary therapy for eosinophilic esophagitis.cited 43× |
| a 4-food elimination diet (dairy, gluten-containing cereals, egg, and legumes) | Increases - have lately developed with good efficacy rates | efficacy rates | Human | children | Not specified | Dietary therapy for eosinophilic esophagitis.cited 43× |
| combined intervention of diet-induced weight loss and exercise | Increases - maximize | self-efficacy | Human | overweight/obese adults with knee OA | Not specified | Effect of intensive diet and exercise on self-efficacy in overweight and obese adults with knee osteoarthritis: The IDEA randomized clinical trial.cited 30× |
| combined intervention of diet-induced weight loss and exercise (D+E) | Increases - reported significantly higher | self-efficacy for balance | Human | overweight/obese older adults with knee OA | Not specified | Effect of intensive diet and exercise on self-efficacy in overweight and obese adults with knee osteoarthritis: The IDEA randomized clinical trial.cited 30× |
| combined intervention of diet-induced weight loss and exercise (D+E) | Increases - reported significantly higher | self-efficacy for gait | Human | overweight/obese older adults with knee OA | Not specified | Effect of intensive diet and exercise on self-efficacy in overweight and obese adults with knee osteoarthritis: The IDEA randomized clinical trial.cited 30× |
| combined intervention of diet-induced weight loss and exercise (D+E) | Increases - reported significantly higher | self-efficacy for walking duration | Human | overweight/obese older adults with knee OA | Not specified | Effect of intensive diet and exercise on self-efficacy in overweight and obese adults with knee osteoarthritis: The IDEA randomized clinical trial.cited 30× |
| Medium Chain Triglyceride (MCT)-KD, modified Atkins diet (MAD) and low glycaemic index treatment (LGIT) | No effect - have an efficacy close to | efficacy | Human | — | Not specified | Alternative diets to the classical ketogenic diet--can we be more liberal?cited 57× |
| ketogenic diet (KD) | Increases - revealed the highest efficacy | efficacy | Human | focal cortical dysplasia (FCD) within the MCD group | Not specified | Effectiveness and safety analysis of ketogenic diet therapy for drug-resistant epilepsy caused by structural pathology. |
| ketogenic diet (KD) | Increases - The efficacy is higher | efficacy | Human | children with MCD, particularly in cases of FCD | Not specified | Effectiveness and safety analysis of ketogenic diet therapy for drug-resistant epilepsy caused by structural pathology. |
| ketogenic diet (KD) | Increases - is a safe and effective treatment | treatment safety and efficacy | Human | drug resistant epilepsy caused by structural etiology | Not specified | Effectiveness and safety analysis of ketogenic diet therapy for drug-resistant epilepsy caused by structural pathology. |
| gluten-free diet (GFD) | No effect - no difference noted | efficacy | Human | — | Not specified | Current evidence for dietary therapies in irritable bowel syndrome.cited 2× |
| low-FODMAP diet (LFD) | No effect - no difference noted | efficacy | Human | — | Not specified | Current evidence for dietary therapies in irritable bowel syndrome.cited 2× |
| maternal high-fat diet (HFD) | Decreases - demonstrated impaired | bronchodilator efficacy | Human | adult male offspring from dams fed a HFD | Not specified | Maternal high fat diet promotes enhanced airway hyperresponsiveness and impaired bronchodilation response in adult male offspring. |
| calorie-restricted Mediterranean diet with targeted dietary supplementation (PROG1) | No effect - confirm the safety, tolerability, and efficacy | safety, tolerability, and efficacy | Human | healthy overweight and obese subjects with cardiometabolic risk factors | ∼68-76% of estimated calorie requirements, including protein shakes and targeted supplementation. | A Low-Glycemic, Mediterranean Diet and Lifestyle Modification Program with Targeted Nutraceuticals Reduces Body Weight, Improves Cardiometabolic Variables and Longevity Biomarkers in Overweight Subjects: A 13-Week Observational Trial.cited 11× |
| iron-rich diet (iron intake >20 mg/die) | No effect - did not support any equivalent efficacy | efficacy | Human | non-anemic iron-deficient women affected by celiac disease | Iron-rich diet (>20 mg/day) versus ferrous sulfate (105 mg/day). | Efficacy of a High-Iron Dietary Intervention in Women with Celiac Disease and Iron Deficiency without Anemia: A Clinical Trial.cited 11× |
| Biologicals and nutraceuticals including overall diet and vitamin D | Increases - have the highest level of evidence for efficacy | efficacy | Human | cancer patients | Not specified | Integrative Approaches for Cancer Pain Management. |
| smartphone application-based diet and exercise improvement program | Increases - significantly improved | dietary self-efficacy | Human | Japanese men living with HIV who have dyslipidemia | Not specified | Effects of a smartphone app-based diet and physical activity program for men living with HIV who have dyslipidemia: A pilot randomized controlled trial.cited 3× |
| Alternatives to gluten free diet | No effect - seem to be still controversial | therapeutic efficacy | Human | patients with refractory celiac disease | Not specified | Diagnosis and management of refractory celiac disease: a systematic review. |
| C10-enriched medium-chain triglyceride (MCT) ketogenic diet (KD) | No effect - demonstrated comparable efficacy and tolerability | efficacy and tolerability | Human | patients with refractory epilepsy who do not respond adequately to the classic KD alone | Not specified | Decanoic acid-enriched ketogenic diet in refractory epilepsy. |
| prescription of a LC diet | Increases - associated with greater | self-efficacy | Human | women | Not specified | PROP Nontaster Women Lose More Weight Following a Low-Carbohydrate Versus a Low-Fat Diet in a Randomized Controlled Trial.cited 4× |
| low fermentable oligo-, di-, monosaccharides and polyols (FODMAP) diet | No effect - is well established | efficacy in irritable bowel syndrome (IBS) | Human | patients with IBS | Not specified (FODMAP powders used in reintroduction phase). | Efficacy and Findings of a Blinded Randomized Reintroduction Phase for the Low FODMAP Diet in Irritable Bowel Syndrome.cited 10× |
| specific carbohydrate diet (SCD) implemented homemade versus chef-prepared | No effect - may influence | efficacy of this dietary therapy | Human | children and adolescents with inflammatory bowel disease (IBD) | Not specified (diet-based intervention). | Differences in Nutrient Intake with Homemade versus Chef-Prepared Specific Carbohydrate Diet Therapy in Inflammatory Bowel Disease: Insights into Dietary Research.cited 2× |
| low-FODMAP diet | Increases - likely efficacy | efficacy | Human | patients with functional dyspepsia (FD) in East and Southeast Asia | Not specified | The low-FODMAP diet in the management of functional dyspepsia in East and Southeast Asia.cited 23× |
| low-FODMAP diet | No effect - do suggest benefit | efficacy | Human | children | Not specified | Controversies and Recent Developments of the Low-FODMAP Diet.cited 83× |
| low-FODMAP diet | No effect - comparable or superior to | efficacy | Human | — | Not specified | Controversies and Recent Developments of the Low-FODMAP Diet.cited 83× |
| low-FODMAP diet | No effect - has been no comparison between | efficacy | Human | — | Not specified | Controversies and Recent Developments of the Low-FODMAP Diet.cited 83× |