Ketogenic Diet
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Evidence suggests Ketogenic Diet maydecreaseBody weight.

9 studies (9 claims)

Emerging evidence

Typical effective dose 84 (55.5–86.95) %across 3 dosed studies

Study Claims

10 of 10

Intervention	Direction	Endpoint	Type	Population	Dosage	Title
low calorie ketogenic nutrition drinks	No effect - investigated the effects	body weight	Human	obese adults	Ketone-to-non-ketone ratios of 4:1 (KD 4:1) and 1.7:1 (KD 1.7:1)	Two-Week Exclusive Supplementation of Modified Ketogenic Nutrition Drink Reserves Lean Body Mass and Improves Blood Lipid Profile in Obese Adults: A Randomized Clinical Trial.cited 30×
ketogenic diet	No effect - could relatively sustain	body weight	Animal	Sprague-Dawley (SD) rats	Different fat-to-carbohydrate ratios under the same apparent metabolizable energy level (specific amounts not provided)	Generalized Ketogenic Diet Induced Liver Impairment and Reduced Probiotics Abundance of Gut Microbiota in Rat.cited 1×
ketogenic diet	Decreases - significant reductions	body weight	Human	overweight or obese polycystic ovary syndrome (PCOS) patients	Not specified.	Impact of short-term ketogenic diet on sex hormones and glucose-lipid metabolism in overweight or obese patients with polycystic ovary syndrome.cited 1×
comprehensive intervention	Decreases - significant reductions	body weight	Human	overweight or obese polycystic ovary syndrome (PCOS) patients	Not specified.	Impact of short-term ketogenic diet on sex hormones and glucose-lipid metabolism in overweight or obese patients with polycystic ovary syndrome.cited 1×
ketogenic diet	Decreases - effectively reducing	body weight	Animal	obesity and diabetes	Not specified	Gut Microbiota Modulates Fgf21 Expression and Metabolic Phenotypes Induced by Ketogenic Diet.
ketogenic diet	Decreases - show reduction in	body weight	Human	participants with obesity	Carbohydrate intake ranged from 7-27% of daily energy	Ketogenic Diet Intervention for Obesity Weight-Loss- A Narrative Review, Challenges, and Open Questions.
ketogenic diet protocol	Decreases - significant loss	body weight	Human	34 male overweight subjects; aged between 25 and 65 years who were overall healthy apart from overweight	Not specified	Effects of n-3 polyunsaturated fatty acids (ω-3) supplementation on some cardiovascular risk factors with a ketogenic Mediterranean diet.cited 52×
hfd	Increases - showed a 15% increase	body weight	Animal	KC mice	KD (%kcal: 84% fat, 15% protein, 1% carbohydrate).	The Impact of a Ketogenic Diet on Late-Stage Pancreatic Carcinogenesis in Mice: Efficacy and Safety Studies.cited 1×
ketogenic diet	Decreases - reduced	body weight	AnimalMolecular	letrozole-induced PCOS mouse model mice	KD with 89.9% (kcal) fat.	A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice.cited 2×
personalized whole food ketogenic diet	Decreases - decreased	body weight	Human	37-year-old obese woman with longstanding OCD and ulcerative colitis	Personalized whole-food ketogenic diet (KMT 1:5:1 ratio).	Remission of OCD and ulcerative colitis with a ketogenic diet: Case Report.