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Evidence suggests Iron mayincreasePerformance.
32 studies (48 claims)
Emerging evidence
Typical effective dose 80 (42–80) mgacross 5 dosed studies
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| iron-biofortified beans | Increases - resulted in improvements | behavioral performance and brain activity | Human | female university students | Daily consumption of iron-biofortified beans (86.1 ppm iron) vs. comparison beans (50.1 ppm iron). | Changes in Iron Status Are Related to Changes in Brain Activity and Behavior in Rwandan Female University Students: Results from a Randomized Controlled Efficacy Trial Involving Iron-Biofortified Beans.cited 21× |
| praziquantel + iron | Increases - improved | school attendance and performance | Human | 7- to 12-year-old anemic children with documented S. haematobium infection | Not specified in the abstract. | Effect on school attendance and performance of iron and multiple micronutrients as adjunct to drug treatment of Schistosoma-infected anemic schoolchildren.cited 5× |
| combined praziquantel and iron treatment | Increases - improved | school attendance and performance | Human | children | Not specified in the abstract. | Effect on school attendance and performance of iron and multiple micronutrients as adjunct to drug treatment of Schistosoma-infected anemic schoolchildren.cited 5× |
| praziquantel + multiple micronutrients + iron | Increases - improved | school attendance and performance | Human | 7- to 12-year-old anemic children with documented S. haematobium infection | Not specified in the abstract. | Effect on school attendance and performance of iron and multiple micronutrients as adjunct to drug treatment of Schistosoma-infected anemic schoolchildren.cited 5× |
| iron supplementation | Increases - may be more beneficial | athletic performance | Human | athletes with ferritin levels <20 μg/L | Not specified | Does Iron Supplementation Improve Performance in Iron-Deficient Nonanemic Athletes?cited 48× |
| iron supplementation | Increases - improved performance | performance | Human | iron-deficient nonanemic (IDNA) athletes | Not specified | Does Iron Supplementation Improve Performance in Iron-Deficient Nonanemic Athletes?cited 48× |
| iron supplementation | No effect - did not improve performance | performance | Human | iron-deficient nonanemic (IDNA) athletes | Not specified | Does Iron Supplementation Improve Performance in Iron-Deficient Nonanemic Athletes?cited 48× |
| iron supplementation | No effect - does not lead to long-term cognitive improvement | cognitive performance | Human | 9-y-old children | Daily supplementation for 6 months (specific dosage not mentioned in the abstract). | Long-term effects of iron and zinc supplementation during infancy on cognitive function at 9 y of age in northeast Thai children: a follow-up study.cited 37× |
| iron supplementation | No effect - No significant differences | performance intelligence quotient | Human | children aged 9 y | Daily supplementation for 6 months (specific dosage not mentioned in the abstract). | Long-term effects of iron and zinc supplementation during infancy on cognitive function at 9 y of age in northeast Thai children: a follow-up study.cited 37× |
| iron plus zinc supplementation | No effect - does not lead to long-term cognitive improvement | cognitive performance | Human | 9-y-old children | Daily supplementation for 6 months (specific dosage not mentioned in the abstract). | Long-term effects of iron and zinc supplementation during infancy on cognitive function at 9 y of age in northeast Thai children: a follow-up study.cited 37× |
| iron plus zinc supplementation | No effect - No significant differences | performance intelligence quotient | Human | children aged 9 y | Daily supplementation for 6 months (specific dosage not mentioned in the abstract). | Long-term effects of iron and zinc supplementation during infancy on cognitive function at 9 y of age in northeast Thai children: a follow-up study.cited 37× |
| iron supplementation | Increases - improves cognitive performance | cognitive performance | Human | women | Not specified for Vitamin A. | Daily iron supplementation for improving anaemia, iron status and health in menstruating women.cited 113× |
| iron supplementation | Increases - improved | maximal and submaximal exercise performance | Human | women | Not specified for Vitamin A. | Daily iron supplementation for improving anaemia, iron status and health in menstruating women.cited 113× |
| iron supplementation | Increases - improve | endurance performance | Human | women | 42 mg elemental iron per day. | Increasing Iron Status through Dietary Supplementation in Iron-Depleted, Sedentary Women Increases Endurance Performance at Both Near-Maximal and Submaximal Exercise Intensities.cited 7× |
| iron supplementation | Increases - increases | endurance performance at submaximal and maximal (VO2peak) exercise intensities | Human | IDNA women | 42 mg elemental iron per day. | Increasing Iron Status through Dietary Supplementation in Iron-Depleted, Sedentary Women Increases Endurance Performance at Both Near-Maximal and Submaximal Exercise Intensities.cited 7× |
| iron supplementation | Decreases - limited the deleterious effects | endurance sport performance | Human | iron-replete young men | 20 mg or 80 mg daily | Iron supplementation limits the deleterious effects of repeated blood donation on endurance sport performance but not on iron status.cited 7× |
| iron supplementation | Increases - seems to be capable of improving | functional performance | Human | — | Not specified | Iron deficiency, fatigue and muscle strength and function in older hospitalized patients.cited 37× |
| iron supplementation | Increases - valued for the perceived benefits of | learning and school performance | Human | adolescents | Not specified | Iron Status, Anemia, and Iron Interventions and Their Associations with Cognitive and Academic Performance in Adolescents: A Systematic Review.cited 35× |
| iron interventions | No effect - impacts of | cognitive and academic performance | Human | adolescents | Not specified | Iron Status, Anemia, and Iron Interventions and Their Associations with Cognitive and Academic Performance in Adolescents: A Systematic Review.cited 35× |
| iron supplementation | Increases - improved | maximal exercise performance | Human | women of reproductive age (WRA) | Daily oral iron supplementation (specific dosage not mentioned) | Iron supplementation benefits physical performance in women of reproductive age: a systematic review and meta-analysis.cited 94× |
| iron supplementation | Increases - improved | submaximal exercise performance | Human | women of reproductive age (WRA) | Daily oral iron supplementation (specific dosage not mentioned) | Iron supplementation benefits physical performance in women of reproductive age: a systematic review and meta-analysis.cited 94× |
| daily iron supplementation | Increases - significantly improves | maximal and submaximal exercise performance | Human | women of reproductive age (WRA) | Daily oral iron supplementation (specific dosage not mentioned) | Iron supplementation benefits physical performance in women of reproductive age: a systematic review and meta-analysis.cited 94× |
| iron supplementation | Decreases - might worse | performance and the clinical outcome | Human | fragile and high-risk patients | Not specified | Clinical management of iron deficiency anemia in adults: Systemic review on advances in diagnosis and treatment.cited 58× |
| iron supplementation | Increases - significant improvement | performance on the majority of functional tests | Human | patients with solid tumors and iron deficiency | Not specified | Impact of Iron-Deficiency Management on Quality of Life in Patients with Cancer: A Prospective Cohort Study (CAMARA Study).cited 6× |
| iron supplementation | No effect - no significant effects on | school performance | Human | children and adolescents | Not specified in the abstract. | Effect of Oral Iron Supplementation on Cognitive Function among Children and Adolescents in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis.cited 7× |
| iron supplementation | No effect - maintained | strength performance | Human | elite female volleyball players | Not specified | Eleven Weeks of Iron Supplementation Does Not Maintain Iron Status for an Entire Competitive Season in Elite Female Volleyball Players: A Follow-Up Study.cited 9× |
| iron supplementation | Increases - experienced greater | strength performance | Human | iron treatment group (ITG) | Not specified | Eleven Weeks of Iron Supplementation Does Not Maintain Iron Status for an Entire Competitive Season in Elite Female Volleyball Players: A Follow-Up Study.cited 9× |
| chronic excess iron intake or underlying genetic conditions | Decreases - can lead to detrimental health consequences and may negatively impact | athletic performance | Human | — | Not specified | The IRONy in Athletic Performance.cited 7× |
| oral iron supplementation | Increases - for performance enhancement | athletic performance | Human | cases of deficiency | Not specified | The IRONy in Athletic Performance.cited 7× |
| impaired iron levels | Decreases - can significantly hinder | athletic performance | Human | athletes | Not specified | The IRONy in Athletic Performance.cited 7× |
| iron overload | Increases - may initially lead to enhanced | performance | Human | — | Not specified | The IRONy in Athletic Performance.cited 7× |
| refining the athletic diet, considering the timing and dosage of iron supplements for deficiency, and implementing chelation therapies for iron overload | Increases - can effectively enhance | athletic performance and overall well-being | Human | — | Not specified | The IRONy in Athletic Performance.cited 7× |
| exercise-induced disturbances in iron homeostasis | Decreases - produce deleterious effects | performance and adaptation to training | Human | athletes | Not mentioned | Effects of an Acute Exercise Bout on Serum Hepcidin Levels.cited 43× |
| intermittent iron supplementation | Decreases - had a negative effect | performance index of the visual search task | Human | schoolchildren | Not specified in the abstract. | Effectiveness of intermittent iron and high-dose vitamin A supplementation on cognitive development of school children in southern Ethiopia: a randomized placebo-controlled trial.cited 2× |
| intravenous iron supplementation | No effect - without concurrent improvements | oxygen transport capacity or performance | Human | trained athletes with no clinical iron deficiency | Three injections of 2 ml (100 mg) intravenous ferric-carboxymaltose over four weeks (weeks 0, 2, 4). | Four weeks of IV iron supplementation reduces perceived fatigue and mood disturbance in distance runners.cited 25× |
| CWs amended with iron-biochar substrates separately (CW-D) | Increases - achieved a higher | total nitrogen removal performance | Molecular | constructed wetlands (CWs) | Micro-oxygen regulation (2 h/d, 60 mL min-1) | Enhanced nitrogen removal in constructed wetlands filled with iron-carbon substrates: Reexploring unique roles of iron-cycling and electroactive microorganisms. |
| Prenatal iron supplementation | Increases - improves | children's health and cognitive performance | Human | children | 20, 40, or 80 mg/day, adjusted based on maternal hemoglobin and iron stores. | Prenatal iron supplementation adjusted to maternal iron stores reduces behavioural problems in 4-year-old children.cited 2× |
| iron intake | Increases - were significantly and positively associated with | physical performance | Human | older adults | Not specified | Minerals and Sarcopenia; The Role of Calcium, Iron, Magnesium, Phosphorus, Potassium, Selenium, Sodium, and Zinc on Muscle Mass, Muscle Strength, and Physical Performance in Older Adults: A Systematic Review.cited 167× |
| iron deficiency | Decreases - negatively affects | cardiovascular performance and quality of life | Human | patients | Not specified | Infections Associated with Iron Administration.cited 5× |
| iron deficiency | Decreases - may affect | physical performance | Human | athletes | Not specified (intermittent oral substitution mentioned). | Iron deficiency in sports - definition, influence on performance and therapy.cited 97× |
| iron deficiency | Decreases - may lead to | worse postoperative outcomes, injury rates, and athletic performance | Human | orthopaedic sports medicine patients | Not available | Malnutrition in Orthopaedic Sports Medicine: A Review of the Current Literature.cited 4× |
| iron oxide/N-doped reduced graphene oxide (Fe2O3/N-rGO) nanocomposites | Increases - improving | electrochemical performance | Molecular | — | Not applicable | A catalytic amplification platform based on Fe2O3 nanoparticles decorated graphene nanocomposites for highly sensitive detection of rutin.cited 1× |
| ID and iron deficiency anemia (IDA) | Decreases - can affect | growth and energy levels as well as motor and cognitive performance | Human | the developing child | Not specified | Iron Nutriture of the Fetus, Neonate, Infant, and Child.cited 59× |
| oral iron supplementation in doses of 100-mg FeSO4·d (approximately 20 mg elemental iron) | Increases - may improve | measures of physical performance | Human | iron-depleted female athletes | 100-mg FeSO4·d (approximately 20 mg elemental iron). | Iron supplementation for female athletes: effects on iron status and performance outcomes.cited 57× |
| parenteral iron supplementation | Increases - established as an important complimentary therapy to improve | patient well-being and physical performance | Human | patients with stable heart failure | Not specified | Iron deficiency in heart failure.cited 56× |
| iron status (serum ferritin) | No effect - no significant associations were observed | cognitive performance | Human | men | Not specified | Midlife iron status is inversely associated with subsequent cognitive performance, particularly in perimenopausal women.cited 11× |
| iron status (hemoglobin) | No effect - No significant findings emerged | cognitive performance | Human | all populations studied | Not specified | Midlife iron status is inversely associated with subsequent cognitive performance, particularly in perimenopausal women.cited 11× |
| oral iron supplementation regime | Increases - to adequately support | health and performance | Human | dancers | Not specified | Dietary Iron and the Elite Dancer.cited 4× |