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Evidence suggests Creatine maydecreaseDepression.
3 studies (5 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| creatine supplementation | No effect - no significant differences were observed | Geriatric Depression Scale scores | Human | older woman | 4 x 5 g/d for 5 days followed by 5 g/d (same as creatine dosage) | Creatine supplementation associated or not with strength training upon emotional and cognitive measures in older women: a randomized double-blind study.cited 48× |
| creatine in addition to cognitive-behavioural therapy (CBT) | Decreases - PHQ-9 scores were lower | Patient Health Questionnaire-9 depression score | Human | participants with depression | Not specified | Efficacy and safety profile of oral creatine monohydrate in add-on to cognitive-behavioural therapy in depression: An 8-week pilot, double-blind, randomised, placebo-controlled feasibility and exploratory trial in an under-resourced area.cited 4× |
| creatine in addition to cognitive-behavioural therapy (CBT) | Decreases - significantly more so in participants taking creatine | Patient Health Questionnaire-9 depression score | Human | participants with depression | Not specified | Efficacy and safety profile of oral creatine monohydrate in add-on to cognitive-behavioural therapy in depression: An 8-week pilot, double-blind, randomised, placebo-controlled feasibility and exploratory trial in an under-resourced area.cited 4× |