4
3
↑4
↓0
—3
Evidence suggests Creatine mayincreaseCreatinine levels.
5 studies (7 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| creatine (Cr) supplementation during a supervised resistance training program | No effect - was normal for Cr participants throughout the intervention | creatinine clearance | Human | postmenopausal women | 0.1 g/kg/day of creatine. | Effects of Creatine and Resistance Training on Bone Health in Postmenopausal Women.cited 51× |
| creatine (CRE) loading in combination with coffee (COF) | Increases - showed increases | serum creatinine (CRN) values | Human | physically active males | 300 mg/day of caffeine anhydrous or 8.9 g/day of coffee (yielding 303 mg of caffeine). | Effects of Coffee and Caffeine Anhydrous Intake During Creatine Loading.cited 10× |
| creatine (CRE) loading | Increases - showed increases | serum creatinine (CRN) values | Human | physically active males | 300 mg/day of caffeine anhydrous or 8.9 g/day of coffee (yielding 303 mg of caffeine). | Effects of Coffee and Caffeine Anhydrous Intake During Creatine Loading.cited 10× |
| creatine (CRE) loading in combination with caffeine anhydrous (CAF) | Increases - showed increases | serum creatinine (CRN) values | Human | physically active males | 300 mg/day of caffeine anhydrous or 8.9 g/day of coffee (yielding 303 mg of caffeine). | Effects of Coffee and Caffeine Anhydrous Intake During Creatine Loading.cited 10× |
| magnesium creatine chelate supplementation | Increases - significantly higher concentration | creatinine concentration | Human | elite soccer players | — | The Effects of Long-Term Magnesium Creatine Chelate Supplementation on Repeated Sprint Ability (RAST) in Elite Soccer Players.cited 15× |
| creatine supplementation | No effect - were unchanged | Creatinine clearance | Human | type 2 diabetic patients | Not specified | Creatine supplementation does not impair kidney function in type 2 diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial.cited 53× |
| creatine supplementation | No effect - No significant difference was found | serum creatinine | Human | Fourteen males | Not specified | The effects of creatine supplementation on thermoregulation and isokinetic muscular performance following acute (3-day) supplementation.cited 8× |