Caffeine
→Memory

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1

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Evidence suggests Caffeine mayincreaseMemory.

6 studies (8 claims)

Emerging evidence

Typical effective dose 20 (20–20) mgacross 1 dosed study

Study Claims

9 of 9

Intervention	Direction	Endpoint	Type	Population	Dosage	Title
a combination of caffeine and nicotine	Increases - enhance	memory	Animal	male C57BL/6J mice	Caffeine (20 mg/kg) combined with nicotine (0.1 mg/kg).	The Effect of a Caffeine and Nicotine Combination on Nicotine Withdrawal Syndrome in Mice.
glucose in combination with caffeine	Increases - enhanced	object working memory	Human	24-hour caffeine deprived habitual caffeine consumers	200 mg caffeine, 2000 mg taurine, and 50 g glucose, administered in various combinations.	Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.cited 85×
caffeine	Increases - enhanced	working memory	Human	24-hour caffeine deprived habitual caffeine consumers	200 mg caffeine, 2000 mg taurine, and 50 g glucose, administered in various combinations.	Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.cited 85×
chronic caffeine administration	No effect - prevented	memory impairment	Animal	adult male Wistar rats	0.3 g/L in drinking water	Caffeine prevents cognitive impairment induced by chronic psychosocial stress and/or high fat-high carbohydrate diet.cited 43×
chronic caffeine administration	No effect - normalizes	memory impairment	Animal	adult male Wistar rats	0.3 g/L in drinking water	Caffeine prevents cognitive impairment induced by chronic psychosocial stress and/or high fat-high carbohydrate diet.cited 43×
chronic caffeine administration	No effect - prevented	stress and/or WD-induced impairment of spatial learning and memory	Animal	adult male Wistar rats	0.3 g/L in drinking water	Caffeine prevents cognitive impairment induced by chronic psychosocial stress and/or high fat-high carbohydrate diet.cited 43×
alpha lipoic acid (LA) and/or caffeine-loaded chitosan nanoparticles (CCNPs)	No effect - evaluated	therapeutic effects on obesity-induced memory impairment	Animal	rats	Not specified	Therapeutic effects of alpha lipoic acid and/or caffeine-loaded chitosan nanoparticles on memory impairment and neurochemical changes in high-fat diet-induced obese rats.
caffeine	Decreases - effectively alleviated	memory impairments caused by chronic hypobaric hypoxia	Animal	male mice	Not specified	Caffeine's Neuroprotective Effect on Memory Impairment: Suppression of Adenosine A2A Receptor and Enhancement of Tyrosine Hydroxylase in Dopaminergic Neurons Under Hypobaric Hypoxia Conditions.
caffeine	Increases - promotes the performance of tasks that involve working memory to a limited extent	performance of tasks that involve working memory	Animal	—	Not available	Protective effect of co-administration of caffeine and piracetam on scopolamine-induced amnesia in Wistar rats.cited 2×