4
2
2
↑4
↓2
—2
Evidence suggests Caffeine mayincreaseHealth benefits.
7 studies (8 claims)
Emerging evidence
Typical effective dose 1 (1–1) mgacross 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| Zn and caffeine | No effect - target hazard quotients were <1 | health risks via the consumption of these tomatoes | Human | human consumers | 1 mg L-1 caffeine trimethyl-13C, applied weekly. | Effects of Caffeine, Zinc, and Their Combined Treatments on the Growth, Yield, Mineral Elements, and Polyphenols of Solanum lycopersicum L.cited 1× |
| excessive caffeine intake | Decreases - is linked to adverse effects | neurological and psychiatric health | Human | — | Not specified (dose-dependent effects noted). | Coffee and mental disorders: How caffeine affects anxiety and depression.cited 1× |
| moderate caffeine consumption | Increases - is safe and may offer benefits | mental health | Human | healthy adults | Not specified (dose-dependent effects noted). | Coffee and mental disorders: How caffeine affects anxiety and depression.cited 1× |
| caffeine-encapsulated titanium oxide nanoparticles (CF-TiO2 NPs) | Increases - improving | systemic oral health | Molecular | — | 20-160 µg/mL | Inhibition of Oral Biofilms and Enhancement of Anticancer Activity on Oral Squamous Carcinoma Cells Using Caffeine-Coated Titanium Oxide Nanoparticles. |
| caffeine | Decreases - potential in mitigating | adverse effects of hypothyroidism on thyroid and heart health | Animal | — | Not specified | Cardiovascular Findings and Effects of Caffeine on Experimental Hypothyroidism.cited 1× |
| caffeine | No effect - no significantly negative effects on human health were proved | human health | Human | human | Not specified | The perspective of caffeine and caffeine derived compounds in therapy.cited 18× |
| balanced administration of vitamin B3, ascorbic acid, vitamin D and the intake of caffeine every day | Increases - seem beneficial | brain health | Human | PD | Not specified | Foods with Potential Prooxidant and Antioxidant Effects Involved in Parkinson's Disease.cited 27× |