4
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↓4
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Evidence suggests Caffeine maydecreaseCognitive decline.
2 studies (4 claims)
Emerging evidence
Typical effective dose 371 (371–371) mgacross 1 dosed study
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| caffeine intake | Decreases - significantly slower rates of cognitive decline | cognitive decline | Human | older women with vascular disorders | Quintiles of caffeine intake, with the highest (>371 mg/day) compared to the lowest (<30 mg/day). | Caffeine and cognitive decline in elderly women at high vascular risk.cited 45× |
| caffeine intake | Decreases - stronger associations | cognitive decline | Human | women assigned to vitamin B supplementation | Quintiles of caffeine intake, with the highest (>371 mg/day) compared to the lowest (<30 mg/day). | Caffeine and cognitive decline in elderly women at high vascular risk.cited 45× |
| caffeine intake | Decreases - equivalent to that observed between those who were 7 years apart in age | cognitive decline rate difference | Human | older women with vascular disorders | Quintiles of caffeine intake, with the highest (>371 mg/day) compared to the lowest (<30 mg/day). | Caffeine and cognitive decline in elderly women at high vascular risk.cited 45× |
| caffeine | Decreases - retards cognitive decline | cognitive decline | Animal | healthy individuals | Not available | Protective effect of co-administration of caffeine and piracetam on scopolamine-induced amnesia in Wistar rats.cited 2× |